These last few days I’ve taken to my bed, not feeling bad but just so very very tired and sleepy. I’m not normally sleepy, and although I’m often fatigued and without energy reserves I would not say I normally feel tired. I did have a busy week before this and it could theoretically just be PEM without any of my normal symptoms. However this exact thing happened at this exact time last year. I was six weeks into my rtx treatment and assumed it was related at the time. For maybe 16-18 days I was completely wiped out, in bed, but with zero pain or other issues. I remember saying I didn’t feel bad at all, just tired. It’s almost a relief in a way, because it feels so “normal”, like the body is for once acting predictably. Then one day I woke up and felt absolutely amazing, and for a week or so I felt like I had almost recovered from ME entirely. This is funnily the exact opposite of what happens when I get a cold. Then I feel amazing for 2-3 days first (cortisol boost maybe?) before the cold breaks out and I’m down and sniveling for a week and a half. Anyway, two episodes a year apart are hardly statistically significant but it is weird that the timing is exactly the same. Could it be the beginning of the pollen season? I have never been allergic to pollen and I would think I should have been affected for the entire season if pollen is it, but ME has made me more sensitive in all sorts of unpredictable ways. Other suggestions? edited for errors.