For 50 years? For the first 20 of those, I don't think much was raised anywhere and it has been going up a lot in the last 20 years. It's not the case that it is some sort of steady amount over the years. Groups like Invest in ME and the Open Medicine Foundation have shown that with enough enthusiasm, new means can be found to fund-raise. But even now there is not much grassroot fundraising (apart from asking people in the ME community to donate) outside the US and the UK. There are all sorts of people in the community. Some are in poverty or close to it, others' situation is not so bad. Given the numbers of people affected, 15-30 million worldwide, people don't have to give or raise that much individually to get a big total. Millions could be raised each year if more people left money in their wills. Even somebody who might not have much when they are alive, may own the property they live in and so have quite a lot they could leave in their will. Some people will not have children that might expect money from their will. Six-figure sums by an individual could be possible in some cases. I saw the 25% ME Group got £180,000 from somebody a couple of years ago. The Nightingale Research Foundation also got some donation like $180,000 in the last few years. One of the big UK ME charities, I can't remember whether it was the ME Association or Action for ME got £300,000-400,000 from somebody in the last few years. So I don't accept any sort of nihilism regarding what can be raised. If people want to lobby because they think it will work, that's fair enough, but I simply don't accept that the massive increase in the amount that has been raised privately in the last 20 years can't be continued when more people put their mind to it. It is coming for a low base in many countries. I accept some people can't donate or fundraise for research but I don't think others should be put off.