vascular

SARS-CoV-2 spike protein receptor-binding domain perturbates intracellular calcium homeostasis and impairs pulmonary vascular endothelial cells Yang, Kai; Liu, Shiyun; Yan, Han; Lu, Wenju; Shan, Xiaoqian; Chen, Haixia; Bao, Changlei; Feng, Huazhuo; Liao, Jing; Liang, Shuxin; Xu, Lei; Tang...

Neurovascular coupling is the concept that in the CNS, organ function is tightly associated with blood flow, moreso than in other organs. Theoretical background and latest thinking — From the introduction in The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in...

Plasma proteome of Long-COVID patients indicates HIF-mediated vasculo-proliferative disease with impact on brain and heart function Iosef, Cristiana; Knauer, Michael J.; Nicholson, Michael; Van Nynatten, Logan R.; Cepinskas, Gediminas; Draghici, Sorin; Han, Victor K. M.; Fraser, Douglas D. Aims...

Long-Term Adverse Effects of Mild COVID-19 Disease on Arterial Stiffness, and Systemic and Central Hemodynamics: A Pre-Post Study Podrug, Mario; Koren, Pjero; Dražić Maras, Edita; Podrug, Josip; Čulić, Viktor; Perissiou, Maria; Bruno, Rosa Maria; Mudnić, Ivana; Boban, Mladen; Jerončić, Ana...

Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation Timon Kuchler; Roman Günthner; Andrea Ribeiro; Renate Hausinger; Lukas Streese; Anna Wöhnl; Veronika Kesseler; Johanna Negele; Tarek Assali; Javier Carbajo-Lozoya...

Wirth and Lohn Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is often associated with various other syndromes or conditions including mast cell activation (MCA), dysmenorrhea and endometriosis, postural tachycardia (POTS) and small fiber neuropathy (SFN). The causes of...

Significance ACh-releasing choline acetyltransferase (ChAT)+ T cells promote vasodilation and regulate blood pressure in mice, but human ChAT+ T cells and the molecular mechanisms by which ChAT-expression is regulated remain undefined. In this study, we identify primary ChAT+ T cells in patients...

Abstract Many individuals who had COVID-19 develop detrimental persistent symptoms; a condition known as post-acute sequelae of COVID-19 (PASC). Despite the elevated risk of cardiovascular disease following COVID-19, limited studies have examined vascular function in PASC with equivocal results...

An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group Vijay Kunadian, Alaide...

Abstract Ebola virus (EBOV) causes severe hemorrhagic fever in humans with high mortality. In Ebola virus disease (EVD) survivors, EBOV persistence in the eyes may break through the inner blood–retinal barrier (iBRB), leading to ocular complications and EVD recurrence. However, the mechanism by...

Sex differences in the vascular response to sympathetic activation during acute hypoxaemia Jacob DW, Harper JL, Ivie CL, Ott EP, Limberg JK Activation of the sympathetic nervous system causes vasoconstriction and a reduction in peripheral blood flow. Sympathetically mediated vasoconstriction...

Abstract Background Long-COVID is characterized by prolonged, diffuse symptoms months after acute COVID-19. Accurate diagnosis and targeted therapies for Long-COVID are lacking. We investigated vascular transformation biomarkers in Long-COVID patients. Methods A case–control study utilizing...

Post with a link to the final paper here ******** Source: Research Square Preprint Date: September 21, 2022 URL: https://www.researchsquare.com/article/rs-2044838/v1 Circadian skin temperature rhythm and dysautonomia in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: the role...

Abstract Background Recent studies have highlighted Coronavirus disease 2019 (COVID-19) as a multisystemic vascular disease. Up to 60% of the patients suffer from long-term sequelae and persistent symptoms even 6 months after the initial infection. Methods This prospective, observational study...

MRI technology finds problems with gas exchange in long COVID https://pubs.rsna.org/doi/10.1148/radiol.221098 The news article is a bit easier to read https://globalnews.ca/news/8950820/long-covid-canadian-researchers-causes-study/ "All 34 of the patients who participated in the study were...

[I'm diagnosed as having Late Stage Lyme with co-infections, one of them being a reactivated herpesvirus. I wasn't sure to post it here or in the "alternative diagnosis" section, I'm sorry if it should have been posted there instead.] In the category 'afraid to ask but important to ask', does...

Preprint: Chronic fatigue associated with post-COVID syndrome versus transient fatigue caused by high intensity exercise: are they comparable in terms of vascular effects? by Michal Chudzik et al Abstract: Purpose: The pathophysiology of chronic fatigue associated with post-COVID syndrome is...

CHRONIC FATIGUE SYNDROME (CFS) AND FIBROMYALGIA ARE VASCULAR DISEASE FREQUENTLY TRIGGERED BY PERSISTENT INTRACELLULAR INFECTIONS. The tissue hypoperfusion and cellular hypoxia that occurs in CFS is associated with dysfunctions of the cells of the vascular walls (endothelial cells and...

Abstract With the ongoing distribution of the coronavirus disease (COVID) vaccines, the pandemic of our age is ending, leaving the world to deal with its well-documented aftereffects. Long COVID comprises a variety of symptoms, of which the neurological component prevails. The most permeating...

Abstract New Findings What is the central question of this study? This study sought to investigate whether central and peripheral hemodynamics during handgrip exercise were different in young adults 3–4 weeks following infection with of SARS-CoV-2 compared with young healthy adults. What...