vascular

Loss of white matter integrity mediates the association between cortical cerebral microinfarcts and cognitive dysfunction: A longitudinal study Jiannan Huang; Megan Oh; Caroline Robert; Xiangyuan Huang; Marco Egle; Daniel J Tozer; Christopher Chen; Saima Hilal Cortical cerebral microinfarcts...

Full title: Infection-induced vascular inflammation in COVID-19 links focal microglial dysfunction with neuropathologies through IL-1/IL-6-related systemic inflammatory states Abstract COVID-19 is associated with diverse neurological abnormalities, which predict poor outcome in patients...

Similar to doing an MOT on a car, scientists believe they can run a blood test to check how fast a person's internal organs are ageing, and even predict which ones might soon fail. The Stanford University team say they can monitor 11 major body parts, including the heart, brain and lungs. They...

Abstract The association between the stiffening of barosensitive regions of central arteries and the derangements in baroreflex functions remains unexplored in COVID-19 survivors. Fifty-seven survivors of mild COVID-19 (defined as presence of upper respiratory tract symptoms and/or fever...

Autoimmune and Autoinflammatory Connective Tissue Disorders Following COVID-19 Sung Ha Lim; Hyun Jeong Ju; Ju Hee Han; Ji Hae Lee; Won-Soo Lee; Jung Min Bae; Solam Lee Importance Multiple cases of autoimmune and autoinflammatory diseases after COVID-19 have been reported. However, their...

Review of Hyperpolarized Pulmonary Functional 129Xe MR for Long-COVID Jim M. Wild; Fergus V. Gleeson; Sarah Svenningsen; James T. Grist; Laura C. Saunders; Guilhem J. Collier; Maksym Sharma; Sam Tcherner; Ali Mozaffaripour; Alexander M. Matheson; Grace Parraga The respiratory consequences of...

SARS-CoV-2 spike protein receptor-binding domain perturbates intracellular calcium homeostasis and impairs pulmonary vascular endothelial cells Yang, Kai; Liu, Shiyun; Yan, Han; Lu, Wenju; Shan, Xiaoqian; Chen, Haixia; Bao, Changlei; Feng, Huazhuo; Liao, Jing; Liang, Shuxin; Xu, Lei; Tang...

Neurovascular coupling is the concept that in the CNS, organ function is tightly associated with blood flow, moreso than in other organs. Theoretical background and latest thinking — From the introduction in The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in...

Plasma proteome of Long-COVID patients indicates HIF-mediated vasculo-proliferative disease with impact on brain and heart function Iosef, Cristiana; Knauer, Michael J.; Nicholson, Michael; Van Nynatten, Logan R.; Cepinskas, Gediminas; Draghici, Sorin; Han, Victor K. M.; Fraser, Douglas D. Aims...

Long-Term Adverse Effects of Mild COVID-19 Disease on Arterial Stiffness, and Systemic and Central Hemodynamics: A Pre-Post Study Podrug, Mario; Koren, Pjero; Dražić Maras, Edita; Podrug, Josip; Čulić, Viktor; Perissiou, Maria; Bruno, Rosa Maria; Mudnić, Ivana; Boban, Mladen; Jerončić, Ana...

Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation Timon Kuchler; Roman Günthner; Andrea Ribeiro; Renate Hausinger; Lukas Streese; Anna Wöhnl; Veronika Kesseler; Johanna Negele; Tarek Assali; Javier Carbajo-Lozoya...

Wirth and Lohn Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is often associated with various other syndromes or conditions including mast cell activation (MCA), dysmenorrhea and endometriosis, postural tachycardia (POTS) and small fiber neuropathy (SFN). The causes of...

Significance ACh-releasing choline acetyltransferase (ChAT)+ T cells promote vasodilation and regulate blood pressure in mice, but human ChAT+ T cells and the molecular mechanisms by which ChAT-expression is regulated remain undefined. In this study, we identify primary ChAT+ T cells in patients...

Abstract Many individuals who had COVID-19 develop detrimental persistent symptoms; a condition known as post-acute sequelae of COVID-19 (PASC). Despite the elevated risk of cardiovascular disease following COVID-19, limited studies have examined vascular function in PASC with equivocal results...

An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group Vijay Kunadian, Alaide...

Abstract Ebola virus (EBOV) causes severe hemorrhagic fever in humans with high mortality. In Ebola virus disease (EVD) survivors, EBOV persistence in the eyes may break through the inner blood–retinal barrier (iBRB), leading to ocular complications and EVD recurrence. However, the mechanism by...

Sex differences in the vascular response to sympathetic activation during acute hypoxaemia Jacob DW, Harper JL, Ivie CL, Ott EP, Limberg JK Activation of the sympathetic nervous system causes vasoconstriction and a reduction in peripheral blood flow. Sympathetically mediated vasoconstriction...

Abstract Background Long-COVID is characterized by prolonged, diffuse symptoms months after acute COVID-19. Accurate diagnosis and targeted therapies for Long-COVID are lacking. We investigated vascular transformation biomarkers in Long-COVID patients. Methods A case–control study utilizing...

Post with a link to the final paper here ******** Source: Research Square Preprint Date: September 21, 2022 URL: https://www.researchsquare.com/article/rs-2044838/v1 Circadian skin temperature rhythm and dysautonomia in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: the role...

Abstract Background Recent studies have highlighted Coronavirus disease 2019 (COVID-19) as a multisystemic vascular disease. Up to 60% of the patients suffer from long-term sequelae and persistent symptoms even 6 months after the initial infection. Methods This prospective, observational study...