treatment

  1. John Mac

    A systematic review of nutraceutical interventions for mitochondrial dysfunctions in ME/CFS, 2021, Marshall-Gradisnik et al

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-02742-4
  2. John Mac

    Insights from Invasive Cardiopulmonary Exercise Testing of Patients with ME/CFS, 2021, Joseph et al

    https://journal.chestnet.org/article/S0012-3692(21)00256-7/fulltext EDIT: also available here: https://www.sciencedirect.com/science/article/abs/pii/S0012369221002567
  3. leokitten

    Selective translocator protein (TSPO) agonists

    Given that there is anecdotal evidence of lorazepam (Ativan) causing rapid temporary improvement of ME symptoms, even in very severe cases, I’ve wondered why ME researchers aren’t looking more closely at researching selective translocator protein (TSPO) agonists. TSPO is also known as the...
  4. Hutan

    Methylphenidate (Ritalin)

    Does Methylphenidate Reduce the Symptoms of Chronic Fatigue Syndrome?, 2006, Blockmans et al There's this 2006 Belgium study.
  5. Andy

    Low-Dose Dextromethorphan for the Treatment of Fibromyalgia Pain: [..] Longitudinal ... Pilot Trial, 2021, Mueller, Ness, Younger

    Full title: Low-Dose Dextromethorphan for the Treatment of Fibromyalgia Pain: Results from a Longitudinal, Single-Blind, Placebo-Controlled Pilot Trial Open access, https://www.dovepress.com/low-dose-dextromethorphan-for-the-treatment-of-fibromyalgia-pain-resul-peer-reviewed-fulltext-article-JPR
  6. Andy

    Open‐label study with the monoamine stabilizer (‐)‐OSU6162 in myalgic encephalomyelitis/chronic fatigue syndrome, Haghighi et al, 2021

    Open access, https://onlinelibrary.wiley.com/doi/full/10.1002/brb3.2040
  7. John Mac

    Review article: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Where Will the Drugs Come From? 2021, Toogood et al

    https://www.sciencedirect.com/science/article/pii/S1043661821000487
  8. Andy

    Journal of Clinical Medicine: Special Issue "Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: Diagnosis and Treatment", 2021

    While I anticipate we will have separate threads for all papers published in this issue, I thought I would highlight the accuracy, or otherwise, of the detail associated with the 'special issue'. Most bolding mine. From https://www.mdpi.com/journal/jcm/special_issues/Chronic_Fatigue A special...
  9. Kitty

    Occupational therapy and ME/CFS

    In my experience of NHS treatment, OTs are the only healthcare professionals who understand how to deal with fatigue. They also know that people's natural response to post-viral illness is not to become fearful of activity, but quite the opposite – they always try to do too much too soon. I've...
  10. Dolphin

    Clinical practice guidelines by the IDSA ... 2020 guidelines for the prevention, diagnosis, and treatment of Lyme disease, 2020, Lantos et al

    https://n.neurology.org/content/neurology/early/2020/11/30/WNL.0000000000011151.full.pdf
  11. Andy

    Lessons Learned from a Rhode Island Academic Out-Patient Lyme and Tick-Borne Disease Clinic, 2020, McCarthy et al

    Abstract on PubMed, https://pubmed.ncbi.nlm.nih.gov/33261237/ Open access, http://rimed.org/rimedicaljournal/2020/12/2020-12-51-contribution-mccarthy.pdf
  12. Dolphin

    Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome, 1997, Plioplys et al

    Copied from this thread https://pubmed.ncbi.nlm.nih.gov/9018019/ Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome A V Plioplys 1, S Plioplys Neurobiology 1997;35(1):16-23. doi: 10.1159/000119325. PMID: 9018019 DOI: 10.1159/000119325 Abstract Carnitine is essential for...
  13. M

    Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19

    Today, I found this preprint on the efficacy of Ivermectin in COVID-19 prophylaxis and treatment. In the context of COVID-19, Ivermectin looks more promising than any other drug I've read results on. The meta-review is partially based on unpublished data, though; it will take time until all the...
  14. J

    Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis..., 2020, Nourbakhsh et al

    Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis: a randomised, placebo-controlled, crossover, double-blind trial https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(20)30354-9/fulltext
  15. Andy

    Effectiveness of Active Therapy-Based Training to Improve the Balance in Patients with Fibromyalgia: A Systematic Review, 2020, Del-Moral-Garcia et al

    Open access, https://www.mdpi.com/2077-0383/9/11/3771/htm
  16. M

    Use of sildenafil (viagra) to alter fatigue, functional status and impaired cerebral blood flow in ... CFS, 2020, Friedman (Pfizer)

    Split from this thread: Exercise Intolerance in Cystic Fibrosis Importance of Skeletal Muscle, 2020, Harris et al Use of sildenafil (Viagra) to alter fatigue, functional status and impaired cerebral blood flow in patients with CFS...
  17. Andy

    OnabotulinumtoxinA Is an Effective Treatment for Chronic Migraine in Patients With Comorbid Fibromyalgia, 2020, Real and de Teran

    Open access, https://www.frontiersin.org/articles/10.3389/fneur.2020.575130/full
  18. MSEsperanza

    The difficulties of conducting intervention trials for the treatment of [ME/CFS]: Expert testimony to NICE guidelines committee by Jonathan Edwards

    Thought it could be helpful to have a thread on Jonathan's expert testimony for any further use and citation. Edwards, Jonathan CW (2020), The difficulties of conducting intervention trials for the treatment of myalgic encephalomyelitis/chronic fatigue syndrome: Expert testimony presented to...
  19. Andy

    Gulf War Illness: Mechanisms Underlying Brain Dysfunction and Promising Therapeutic Strategies, 2020, Shetty et al

    Paywall, https://www.sciencedirect.com/science/article/abs/pii/S0163725820302473 Sci hub, https://sci-hub.se/10.1016/j.pharmthera.2020.107716
  20. John Mac

    Open A Trial of Solriamfetol in the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Joel L Young, 2020

    https://www.clinicaltrials.gov/ct2/show/NCT04622293 https://thejewishnews.com/2020/10/07/new-hope-for-chronic-fatigue-sufferers/
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