Role of the complement system in Long COVID
Vadim Farztdinov; Boris Zuehlke; Franziska Sotzny; Fridolin Steinbeis; Martina Seifert; Claudia Kedor; Kirsten Wittke; Pinkus Tober-Lau; Kathrin Textoris-Taube; Daniela Ludwig; Clemens Dierks; Dominik Bierbaum; Leif Erik Sander; Leif Gunnar Hanitsch...
Systemic Genome Correlation Loss as a Central Characteristic of Spaceflight
Anurag Sakharkar; Kiven Erique Lukong; Lauren M Sanders; Sylvain V Costes; Jian Yang; Changiz Taghibiglou
Space exploration has captured the imagination of humanity for generations. From the first steps on the moon to...
Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network
Lee, Richard G.; Rudler, Danielle L.; Raven, Samuel A.; Peng, Liuyu; Chopin, Anaëlle; Moh, Edward S. X.; McCubbin, Tim; Siira, Stefan J.; Fagan, Samuel V.; DeBono, Nicholas J.; Stentenbach, Maike...
Global organelle profiling reveals subcellular localization and remodeling at proteome scale
Marco Y Hein; Duo Peng; Verina Todorova; Frank McCarthy; Kibeom Kim; Chad Liu; Laura Savy; Camille Januel; Rodrigo Baltazar-Nunez; Sophie Bax; Shivanshi Vaid; Madhuri Vangipuram; Ivan E Ivanov; Janie R...
Nanobodies as novel tools to monitor the mitochondrial fission factor Drp1
Theresa Froehlich; Andreas Jenner; Claudia Cavarischia-Rega; Funmilayo O. Fagbadebo; Yannic Lurz; Desiree I. Frecot; Philipp D. Kaiser; Stefan Nueske; Armin Scholz; Erik Schaeffer; Ana J. Garcia-Saez; Boris Macek; Ulrich...
Similar to doing an MOT on a car, scientists believe they can run a blood test to check how fast a person's internal organs are ageing, and even predict which ones might soon fail.
The Stanford University team say they can monitor 11 major body parts, including the heart, brain and lungs.
They...
Proteomic Evolution from Acute to Post-COVID-19 Conditions
Yassene Mohammed; Karen Tran; Chris Carlsten; Christopher Ryerson; Alyson Wong; Terry Lee; Matthew P. Cheng; Donald C. Vinh; Todd C. Lee; Brent W. Winston; David Sweet; John H. Boyd; Keith R. Walley; Greg Haljan; Allison McGeer; Francois...
A foundational atlas of autism protein interactions reveals molecular convergence
Belinda Wang; Rasika Vartak; Yefim Zaltsman; Zun Zar Chi Naing; Kelsey M Hennick; Benjamin J Polacco; Ali Bashir; Manon Eckhardt; Mehdi Bouhaddou; Jiewei Xu; Nawei Sun; Micaela Lasser; Yuan Zhou; Keelan Z Guiley...
Full Title: Dysregulations in hemostasis, metabolism, immune response, and angiogenesis in post-acute COVID-19 with and without POTS syndrome; a multi-omic profiling study, 2023, Ali Mahdi et al
Abstract
Post-acute COVID-19 (PACS) are associated with cardiovascular dysfunction, especially...
Understanding COVID-19 progression with longitudinal peripheral blood mononuclear cell proteomics: Changes in the cellular proteome over time
Giuseppe Gianini Figueirêdo Leite; Milena Karina Colo Brunialti; Paula M. Peçanha-Pietrobom; Paulo R. Abrão Ferreira; Jaquelina Sonoe Ota-Arakaki; Edecio...
Cerebrospinal Fluid Proteomic Profiles in Patients with Postherpetic Neuralgia
Kai Chen; Meng Wang; Dongju Long; Dingquan Zou; Xin Li; Ruixuan Wang; Yaping Wang; Lin Yang
The intrinsic mechanism of postherpetic neuralgia (PHN) remains unclear. Herein, we aimed to seek the hub proteins in the...
Probing long COVID through a proteomic lens: a comprehensive two-year longitudinal cohort study of hospitalised survivors
Background
As a debilitating condition that can impact a whole spectrum of people and involve multi-organ systems, long COVID has aroused the most attention than ever...
https://www.researchsquare.com/article/rs-3335919/v1
Article
Immune cell proteomes of Long COVID patients have functional changes similar to those in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Katie Peppercorn1
Christina D. Edgar1
Torsten Kleffmann1
Warren. P Tate1
Email
1...
Plasma proteomics show altered inflammatory and mitochondrial proteins in patients with neurologic symptoms of post-acute sequelae of SARS-CoV-2 infection
Hanson; Visvabharathy; Orban; Jimenez; Batra; Liotta; DeLisle; Klausner; Cohen; Padhye; Tachas; Koralnik
Persistent symptoms of COVID-19...
Discussion split from discussion of an NIH webinar where there was a presentation of a forthcoming Bergquist CSF proteomics study USA: NIH National Institutes of Health news
Does anyone know if CSF proteomics has been used to study other illnesses?
Distinct molecular profiles of skull bone marrow in health and neurological disorders
Zeynep Ilgin Kolabas; Louis B. Kuemmerle; Robert Perneczky; Benjamin Förstera; Selin Ulukaya; Mayar Ali; Saketh Kapoor; Laura M. Bartos; Maren Büttner; Ozum Sehnaz Caliskan; Zhouyi Rong; Hongcheng Mai; Luciano...
Persistent immune and clotting dysfunction detected in saliva and blood plasma after COVID-19
Hyesun Jang; Saibyasachi Choudhury; Yanbao Yu; Benjamin L. Sievers; Terri Gelbart; Harinder Singh; Stephen A. Rawlings; Amy Proal; Gene S. Tan; Yu Qian; Davey Smith; Marcelo Freire
A growing number of...
Chronic inflammation, neutrophil activity, and autoreactivity splits long COVID
Abstract
While immunologic correlates of COVID-19 have been widely reported, their associations with post-acute sequelae of COVID-19 (PASC) remain less clear. Due to the wide array of PASC presentations...
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