proteomics

  1. SNT Gatchaman

    [Preprint] Immunometabolic rewiring in long COVID patients with chronic headache, 2023, Cleveland Clinic

    Immunometabolic rewiring in long COVID patients with chronic headache Suan-Sin Foo, Weiqiang Chen, Kyle L Jung, Tamiris Azamor, Un Yung Choi, Pengfei Zhang, Suzy AA Comhair, Serpil C Erzurum, Lara Jehi, Jae U Jung Almost 20% of patients with COVID-19 experience long-term effects, known as...
    • SNT Gatchaman
    • Thread
    • arginine ceramide gaba headache immunometabolic kynurenine lipid metabolism lipids long covid metabolomics nitric oxide pro-inflammatory proteomics serotonin sphingomyelin
    • Replies: 0
    • Forum: Long Covid research
  2. B

    Organ and cell-specific biomarkers of Long-COVID identified with targeted proteomics and machine learning, 2023, Patel et al

    https://molmed.biomedcentral.com/articles/10.1186/s10020-023-00610-z Background Survivors of acute COVID-19 often suffer prolonged, diffuse symptoms post-infection, referred to as “Long-COVID”. A lack of Long-COVID biomarkers and pathophysiological mechanisms limits effective diagnosis...
  3. mango

    Plasma proteomic profiling in ... POTS reveals new disease pathways, 2022, Johansson et al

    Plasma proteomic profiling in postural orthostatic tachycardia syndrome (POTS) reveals new disease pathways Madeleine Johansson, Hong Yan, Charlotte Welinder, Ákos Végvári, Viktor Hamrefors, Magnus Bäck, Richard Sutton & Artur Fedorowski. Abstract Postural orthostatic tachycardia syndrome...
  4. Sly Saint

    Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and fibromyalgia are indistinguishable by their cerebrospinal fluid proteomes 2022, Schutzer et al

    Steven E Schutzer, Tao Liu, Chia-Feng Tsai, Vladislav A Petyuk, Athena Schepmoes, Yi-Ting Wang, Karl Weitz, Jonas Bergquist, Richard Smith, Benjamin Natelson preprint Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and fibromyalgia have overlapping neurologic symptoms...
    • Sly Saint
    • Thread
    • bergquist cerebrospinal fluid csf fibromyalgia me/cfs proteomics schutzer
    • Replies: 14
    • Forum: ME/CFS research
  5. cassava7

    Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device, Reed et al, 2022

    Single-molecule reading of proteins Modern DNA-sequencing methods can interrogate single molecules in extremely high throughput, but protein sequencing typically uses ensemble techniques and requires larger amounts of relatively pure material. Reed et al. generated a set of labeled proteins...
  6. John Mac

    Plasma proteomic signature predicts who will get persistent symptoms following SARS-CoV-2 infection, Captur et al, 2022

    Background The majority of those infected by ancestral Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) during the UK first wave (starting March 2020) did not require hospitalisation. Most had a short-lived mild or asymptomatic infection, while others had symptoms that persisted for...
  7. Sly Saint

    The Urinary Proteomic Profile Implicates Key Regulators for Urologic Chronic Pelvic Pain Syndrome (UCPPS), 2022, Froehlich et al

    How chronic pain shows up in urine - Researchers distinguish urinary pelvic pain from healthy controls — and from other chronic pain diseases full article and link to research paper https://www.asbmb.org/asbmb-today/science/051022/how-chronic-pain-shows-up-in-urine
  8. Kalliope

    Immuno-proteomic profiling reveals aberrant immune cell regulation in [airways in post-COVID-19 respiratory disease], 2022, Vijayakumar et al

    Immunity: Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways of individuals with ongoing post-COVID-19 respiratory disease by Bavithra Vijayakumar et al Highlights Post-COVID-19 airways, but not blood, show immune and proteomic changes Different post-COVID-19...
  9. Trish

    Open UK - Recruiting: Novel Dynamic Proteomics Approaches to Investigate the Systems Level Pathology of ME/CFS

    Recruiting: Novel Dynamic Proteomics Approaches to Investigate the Systems Level Pathology of ME/CFS Dr Daniel Wilkinson, Prof Philip Atherton, Prof Ken Smith, Dr Bethan Phillips, Dr John Williams, Dr Mathew Piasecki (Project Investigators). Nottingham University UK ME Association article...
  10. leokitten

    Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19, 2021, Lee et al

    Pure speculation but maybe this line of research or the methods used in the paper to understand immune cell metabolic reprogramming via single-cell multiomics could eventually help explain whatever possible cellular metabolic changes that are triggered and persist in Long COVID and ME/CFS…...
  11. Kalliope

    biomolecules: Bioenergetic and Proteomic Profiling of Immune Cells in ME/CFS Patients: An Exploratory Study - Fernandez-Guerra et al - 2021

    biomolecules: Bioenergetic and Proteomic Profiling of Immune Cells in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients: An Exploratory Study Fernandes-Guerra et al Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a heterogeneous, debilitating, and complex...
    • Kalliope
    • Thread
    • 2021 acetyl co a atp coenzyme a denmark fernandez-guerra me/cfs metabolomics mitochondria mitochondrial dysfunction paper proteomics pyruvate dehydrogenase complex seahorse
    • Replies: 9
    • Forum: ME/CFS research
  12. John Mac

    Dysregulated Provision of Oxidisable Substrates to the Mitochondria in ME/CFS Lymphoblasts, 2021, Missailidis et al

    https://www.mdpi.com/1422-0067/22/4/2046
    • John Mac
    • Thread
    • amino acid catabolism beta-oxidation fisher glycolysis me/cfs missailidis mitochondria proteomics tca cycle transcriptomics
    • Replies: 68
    • Forum: ME/CFS research
  13. John Mac

    In-Depth Analysis of the Plasma Proteome in ME/CFS Exposes Disrupted Ephrin-Eph and Immune System Signaling, 2021, Hanson et al

    https://www.mdpi.com/2227-7382/9/1/6
    • John Mac
    • Thread
    • adherens junction ephrin ephrin-eph pathway germain glucose immune metabolism levine maureen hanson me/cfs plasma proteomics susan levine
    • Replies: 42
    • Forum: ME/CFS research
  14. ME/CFS Skeptic

    Multi-omics Examination of Q Fever Fatigue Syndrome Identifies Similarities with Chronic Fatigue Syndrome (Preprint, 2020) Raijmakers et al.

    Abstract: Full preprint available at: https://www.researchsquare.com/article/rs-54097/v1
    • ME/CFS Skeptic
    • Thread
    • 2020 4e-bp1 integrins me/cfs metabolomics microbiome mmp-1 paper proteomics q fever q fever fatigue syndrome raijmakers van der meer
    • Replies: 16
    • Forum: ME/CFS research
  15. Sly Saint

    A SWATH-MS analysis of ME/CFS peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction: Sweetman,Vallings,Tate et al Aug 2020

    A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction https://www.researchsquare.com/article/rs-52172/v1
    • Sly Saint
    • Thread
    • 2020 me/cfs metabolism mitochondria mitochondrial dysfunction paper peroxiredoxin proteomics ros vallings sweetman warren tate
    • Replies: 17
    • Forum: ME/CFS research
  16. Andy

    Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS, 2020, Lipkin et al

    Open access, https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0236148
    • Andy
    • Thread
    • 2020 b cell receptor b cells camp kinase inhibitor lipkin lymphoma me/cfs paper proteomics
    • Replies: 31
    • Forum: ME/CFS research
  17. Obermann

    Distinct Cerebrospinal Fluid Proteomes Differentiate Post-Treatment Lyme Disease from CFS, 2011, Schutzer et al.

    Abstract Background: Neurologic Post Treatment Lyme disease (nPTLS) and Chronic Fatigue (CFS) are syndromes of unknown etiology. They share features of fatigue and cognitive dysfunction, making it difficult to differentiate them. Unresolved is whether nPTLS is a subset of CFS. Methods and...
    • Obermann
    • Thread
    • 2011 cerebral spinal fluid lyme me/cfs natelson paper proteomics schutzer
    • Replies: 13
    • Forum: ME/CFS research
  18. Indigophoton

    Multiomics and Human Diseases

    A set of very short (one paragraph) descriptions of the various "omics": genomics, epigenomics, transcriptomics, proteomics, metabolomics and microbiomics. There are also brief videos for each. https://www.news-medical.net/amp/health/Multiomics-and-Human-Diseases.aspx?
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