paper

Hypoxanthine (Hx), an intermediate metabolite of the purine metabolism pathway which is dramatically increased in blood and skeletal muscle during muscle contraction and metabolism, is characterized as a marker of exercise exhaustion. However, the physiological effects of Hx on skeletal muscle...

View ORCID ProfileJoao Torrado Malato, View ORCID ProfileLuis Graca, View ORCID ProfileLuis Nacul, View ORCID ProfileEliana Mattos Lacerda, View ORCID ProfileNuno Sepulveda Preprint Abstract Given the absence of a disease-specific biomarker, there are more than 20 symptoms-based case...

Abstract Background: The aim of this registry study was the prospective evaluation of the efficacy of Pycnogenol® in idiopathic fibromyalgia (FM), over 4 weeks in comparison with the standard management (SM). Methods: A SM and a Pycnogenol®+SM group were formed. Pycnogenol® supplementation...

A comprehensive clinical and laboratory evaluation of 224 patients with persistent symptoms attributed to presumed tick-bite exposure Abstract Background: Persistent symptoms attributed to presumed tick-bite exposure constitute an unresolved medical controversy. We evaluated whether Swedish...

Abstract Functional neurological disorder (FND) is a prevalent, disabling and costly condition at the neurology–psychiatry intersection. After being marginalised in the late 20th century, there has been renewed interest in this field. In this article, we review advances that have occurred over...

Abstract Objective Functional dystonia (FD) is a disabling and diagnostically challenging functional movement disorder (FMD). We sought to identify historical predictors of FD vs. other primary dystonias (ODs) and develop a practical prediction algorithm to guide neurologists. Methods 1475...

Full title: An exploratory study of discrepancies between objective and subjective measurement of the physical activity level in female patients with chronic fatigue syndrome Highlights • There is a discrepancy between self-report and objective activity measures in CFS. • The activity diary...

https://portlandpress.com/clinsci/article-abstract/118/2/125/68670 Scihub 2010 paper Barry Hurwitz; Virginia Coryell; Meela Parker; Pedro Martin; Arthur LaPerriere; Nancy Klimas; George Sfakianakis; Martin Bilsker Abstract The study examined whether deficits in cardiac output and blood volume...

Mini Review ARTICLE Marta Lombardi1, Martina Gabrielli1, Elena Adinolfi2 and Claudia Verderio1* 1CNR Institute of Neuroscience, Research Labs–University Milano-Bicocca, Vedano al Lambro, Italy 2Department of Medical Sciences, Section of Experimental Medicine, University of Ferrara, Ferrara...

Based on experience with past coronaviruses, the emerging challenge of prolonged symptoms after infection with the novel coronavirus 2019 (SARS-CoV-2) is unsurprising. Data from a large international web-based patient survey indicate substantial symptom overlap between long COVID and myalgic...

Highlights • Bloodborne C. albicans infection altered the gut microbiota and metabolites. • Bloodborne C. albicans infection caused intestinal damage. • Perturbations in intestinal flora and metabolism may exacerbate intestinal damage. • Altered gut microbiota and metabolites may provide new...

https://www.ruh.nhs.uk/patients/services/clinical_depts/paediatric_cfs_me/index.asp https://www.ruh.nhs.uk/patients/services/clinical_depts/paediatric_cfs_me/documents/POMME_Study_Info_June 2020.pdf eta: an apple a day keeps the doctor away?

Preprint. " Abstract Finite mixture models have been widely used in antibody (or serological) data analysis in order to help classifying individuals into either antibody-positive or antibody-negative. The most popular models are the so-called Gaussian mixture models which assume a Normal...

Full title: Persistent Suffering: The Serious Consequences of Sexual Violence against Women and Girls, Their Search for Inner Healing and the Significance of the #MeToo Movement This paper uses the method of theory synthesis, primarily from our own previous studies and psychoneuroimmunology...

https://www.frontiersin.org/articles/10.3389/fimmu.2017.00723/full Correction article https://www.frontiersin.org/articles/10.3389/fimmu.2019.00350/full

Full title: The Neuroinflammatory Etiopathology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) https://www.frontiersin.org/articles/10.3389/fphys.2017.00088/full

Full title: Reduced endothelial function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - results from open-label cyclophosphamide intervention study Provisionally accepted https://www.frontiersin.org/articles/10.3389/fmed.2021.642710/abstract

Full title: Cost-effectiveness of Interventions for Chronic Fatigue Syndrome or Myalgic Encephalomyelitis: A Systematic Review of Economic Evaluations Open access, https://link.springer.com/article/10.1007/s40258-021-00635-7

Recursive ensemble feature selection provides a robust mRNA expression signature for myalgic encephalomyelitis/chronic fatigue syndrome https://www.nature.com/articles/s41598-021-83660-9

Paywall, https://www.tandfonline.com/doi/full/10.1080/09638288.2021.1887946