mitochondrial dysfunction

  1. D

    Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers, Flockhart et al, 2021

    https://doi.org/10.1016/j.cmet.2021.02.017 "Exercise training positively affects metabolic health through increased mitochondrial oxidative capacity and improved glucose regulation and is the first line of treatment in several metabolic diseases. However, the upper limit of the amount of...
  2. John Mac

    A systematic review of nutraceutical interventions for mitochondrial dysfunctions in ME/CFS, 2021, Marshall-Gradisnik et al

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-02742-4
    • John Mac
    • Thread
    • 2021 marshall-gradisnik mitochondria mitochondrial dysfunction nutraceutical review staines treatment
    • Replies: 3
    • Forum: ME/CFS research news
  3. Andy

    Mitochondria-derived methylmalonic acid, a surrogate biomarker of mitochondrial dysfunction and oxidative stress..., 2020, Wang et al

    Full title: Mitochondria-derived methylmalonic acid, a surrogate biomarker of mitochondrial dysfunction and oxidative stress, predicts all-cause and cardiovascular mortality in the general population Open access, https://www.sciencedirect.com/science/article/pii/S2213231720309460
  4. Andy

    Pre-print: Innate immune signaling & sex differences contribute to [..] impairment, neuroinflammation, & mitochondrial rewiring in [GWI], 2020, Bryant

    Full title: Innate immune signaling and sex differences contribute to neurocognitive impairment, neuroinflammation, and mitochondrial rewiring in a mouse model of Gulf War illness https://www.biorxiv.org/content/10.1101/2020.08.28.271833v1
  5. Sly Saint

    A SWATH-MS analysis of ME/CFS peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction: Sweetman,Vallings,Tate et al Aug 2020

    A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction https://www.researchsquare.com/article/rs-52172/v1
    • Sly Saint
    • Thread
    • 2020 me/cfs metabolism mitochondria mitochondrial dysfunction paper peroxiredoxin proteomics ros vallings sweetman warren tate
    • Replies: 17
    • Forum: ME/CFS research
  6. Hutan

    Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione..., 2012, Shungu et al

    Abstract Chronic fatigue syndrome (CFS) is a complex illness, which is often misdiagnosed as a psychiatric illness. In two previous reports, using 1H MRSI, we found significantly higher levels of ventricular cerebrospinal fluid (CSF) lactate in patients with CFS relative to those with...
    • Hutan
    • Thread
    • 2012 cerebral hypoperfusion cerebral spinal fluid gsh lactate me/cfs mitochondrial dysfunction neuroimaging paper shungu
    • Replies: 2
    • Forum: ME/CFS research
  7. cassava7

    Mitochondrial Functions in Infection and Immunity, 2020, Tiku et al.

    Thought this review might be interesting/in line with Bhupesh Prusty's work on HHV-6 causing mitochondrial damage (fission) via a miRNA mechanism. Open access: https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(20)30018-0 Amy Proal has tweeted about it:
  8. Andy

    Gut Dysbiosis Dysregulates Central and Systemic Homeostasis via Suboptimal Mitochondrial Function..., 2020, Anderson and Maes

    Full title: Gut Dysbiosis Dysregulates Central and Systemic Homeostasis via Suboptimal Mitochondrial Function: Assessment, Treatment and Classification Implications Paywall, http://www.eurekaselect.com/178870/article Not available via Sci hub at time of posting.
    • Andy
    • Thread
    • 2020 butyrate dysbiosis gut microbiome leaky gut maes microbiome mitochondria mitochondrial dysfunction paper
    • Replies: 0
    • Forum: Other health news and research
  9. R

    Changes in the transcriptome of circulating immune cells of a NZ cohort with ME/CFS (2019) Sweetman et al

    I saw this posted on the "ME/CFS-Evolving Science" facebook page... Changes in the transcriptome of circulating immune cells of a New Zealand cohort with myalgic encephalomyelitis/chronic fatigue syndrome Eiren Sweetman, Margaret Ryan, Christina Edgar, Angus MacKay, Rosamund Vallings, Warren...
    • RoseE
    • Thread
    • 2019 circadian inflammation me/cfs metabolic dysregulation mitochondria mitochondrial dysfunction new zealand oxidative stress paper sweetman transcriptome
    • Replies: 21
    • Forum: ME/CFS research
  10. H

    Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis (2018)

    I thought some others might also find this interesting. I have EoE and my EoE and stomach problems flare from exertion and it's becoming pretty obvious it's playing quite a big role in my disease. I've also suspected that I have severe mitochondrial dysfunction in these organs but unable to...
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