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mitochondrial dysfunction

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  1. Tom Kindlon
    Thread

    Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and mitochondria: A review, 2022, Pandey (M.Sc. Thesis)

    via Dr. Marc-Alexander Fluks Source: Cornell University Date: May 2022 URL: https://ecommons.cornell.edu/handle/1813/111644...
    Thread by: Tom Kindlon, Sep 20, 2022, 2 replies, in forum: ME/CFS research
  2. SNT Gatchaman
    Thread

    Myopathy as a cause of fatigue in long-term post-COVID-19 symptoms: Evidence of skeletal muscle histopathology, 2022, Hejbøl et al

    Myopathy as a cause of fatigue in long-term post-COVID-19 symptoms: Evidence of skeletal muscle histopathology Eva K Hejbøl, Thomas Harbo, Jane...
    Thread by: SNT Gatchaman, Jun 7, 2022, 8 replies, in forum: Long Covid research
  3. Andy
    Thread

    A time-dependently regulated gene network reveals that Aspergillus protease affects mitochondrial metabolism and airway epithelial..., 2022, Kim et al

    Full title: A time-dependently regulated gene network reveals that Aspergillus protease affects mitochondrial metabolism and airway epithelial...
    Thread by: Andy, May 1, 2022, 0 replies, in forum: Other health news and research
  4. Kalliope
    Thread

    Journal of Leukocyte Biology - Loss of mitochondrial membrane potential (ΔΨm) in leucocytes as post-COVID-19 sequelae, Díaz-Resendiz et al, 2022

    Abstract The mitochondrial membrane potential (ΔΨm) is a parameter often used to determine mitochondrial function; therefore, it can be used to...
    Thread by: Kalliope, Mar 31, 2022, 3 replies, in forum: Long Covid research
  5. Andy
    Thread

    Does Dietary Coenzyme Q10 + Selenium Supplementation Ameliorate Clinical Outcomes by Modulating Oxidative Stress & Inflammation., 2022, Castro-Marrero

    Full title: Does Dietary Coenzyme Q10 plus Selenium Supplementation Ameliorate Clinical Outcomes by Modulating Oxidative Stress and Inflammation...
    Thread by: Andy, Mar 3, 2022, 4 replies, in forum: ME/CFS research
  6. darrellpf
    Thread

    Reneo Pharmaceuticals Announces Notice of Allowance for Patent Application on REN001

    "Reneo is a clinical stage pharmaceutical company focused on the development and commercialization of therapies for patients with rare genetic...
    Thread by: darrellpf, Dec 16, 2021, 0 replies, in forum: Other health news and research
  7. Rossy191276
    Thread

    What differentiates ME/CFS from known primary mitochondrial diseases; could mitochondrial disease cause PEM?

    I put this post here as I couldn't see a section for Primary Mitochondrial Disease in Missed/Alternative Diagnosis section... Given the advice...
    Thread by: Rossy191276, Nov 18, 2017, 63 replies, in forum: Possible causes and predisposing factor discussion
  8. Sly Saint
    Thread

    Podcast: Mitochondrial Dysfunction and Autism with Dr. Richard G. Boles

    not listened to it so no idea of content. In this episode I welcome on Dr. Richard Boles. Dr. Richard G. Boles is a medical geneticist and a...
    Thread by: Sly Saint, Dec 7, 2021, 1 replies, in forum: Other health news and research
  9. Andy
    Thread

    Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress...., 2021, Nunes et al

    Full title: Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the...
    Thread by: Andy, Dec 7, 2021, 3 replies, in forum: Other health news and research
  10. Fizzlou
    Thread

    ME/CFS, FM: Mitochondrial dysfunction ... cellular hypoxia, hypoperfusion, endothelial dysfunction, persistent clots, 2021, Chang, Figueredo

    Posts copied from The micro-clot finding in Long Covid — implications for the possible aetiology of ME/CFS...
    Thread by: Fizzlou, Nov 8, 2021, 8 replies, in forum: ME/CFS research
  11. Jacob Richter
    Thread

    Use of whole genome sequencing to determine genetic basis of suspected mitochondrial disorders: cohort study, 2021, Schon et al.

    Posts moved from this thread: Trial of Long Covid treatment - AXA1125 from Axcella Therapeutics, 2021 ________________ Use of whole genome...
    Thread by: Jacob Richter, Nov 6, 2021, 7 replies, in forum: Other health news and research
  12. Andy
    Thread

    Targeting Mitochondrial Network Disorganization is Protective in C. elegans Models of Huntington’s Disease, 2021, Machiela et al

    In worms. Abstract Huntington’s disease (HD) is an adult-onset neurodegenerative disease caused by a trinucleotide CAG repeat expansion in the...
    Thread by: Andy, Oct 12, 2021, 0 replies, in forum: Other health news and research
  13. Andy
    Thread

    Blood cell respiration rates and mtDNA copy number: a promising tool for the diagnosis of mitochondrial disease, 2021, Alonso et al

    Highlights • Mitochondrial respiration decreases with age in PBMCs from healthy individuals. • PBMC mtDNA copy number increases in patients with...
    Thread by: Andy, Sep 19, 2021, 0 replies, in forum: Other health news and research
  14. Andy
    Thread

    Porphyromonas gingivalis infection promotes mitochondrial dysfunction through Drp1-dependent mitochondrial fission in endothelial cells, 2021,Xu et al

    Abstract Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, has been shown to accelerate the progression of...
    Thread by: Andy, Sep 4, 2021, 0 replies, in forum: Other health news and research
  15. Kalliope
    Thread

    biomolecules: Bioenergetic and Proteomic Profiling of Immune Cells in ME/CFS Patients: An Exploratory Study - Fernandez-Guerra et al - 2021

    biomolecules: Bioenergetic and Proteomic Profiling of Immune Cells in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients: An Exploratory...
    Thread by: Kalliope, Jun 29, 2021, 9 replies, in forum: ME/CFS research
  16. Andy
    Thread

    Lupus susceptibility gene Esrrg modulates regulatory T cells through mitochondrial metabolism, 2021, Li et al

    Abstract. Estrogen-related receptor gamma (Esrrg) is a murine lupus susceptibility gene associated with T cell activation. Here, we report that...
    Thread by: Andy, Jun 23, 2021, 0 replies, in forum: Other health news and research
  17. Andy
    Thread

    Dysfunctional mitochondria as critical players in the inflammation of autoimmune diseases: Potential role in Sjögren’s syndrome, 2021, Barrera et al

    Highlights • Chronic inflammation can be caused by organelle (e.g., mitochondria) malfunction. • Dysfunctional mitochondria release DAMPs that...
    Thread by: Andy, Jun 13, 2021, 0 replies, in forum: Other health news and research
  18. darrellpf
    Thread

    Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers, Flockhart et al, 2021

    https://doi.org/10.1016/j.cmet.2021.02.017 "Exercise training positively affects metabolic health through increased mitochondrial oxidative...
    Thread by: darrellpf, Mar 19, 2021, 4 replies, in forum: Other health news and research
  19. John Mac
    Thread

    A systematic review of nutraceutical interventions for mitochondrial dysfunctions in ME/CFS, 2021, Marshall-Gradisnik et al

    Abstract Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating illness, characterised by persistent fatigue...
    Thread by: John Mac, Feb 18, 2021, 3 replies, in forum: ME/CFS research news
  20. Andy
    Thread

    Mitochondria-derived methylmalonic acid, a surrogate biomarker of mitochondrial dysfunction and oxidative stress..., 2020, Wang et al

    Full title: Mitochondria-derived methylmalonic acid, a surrogate biomarker of mitochondrial dysfunction and oxidative stress, predicts all-cause...
    Thread by: Andy, Oct 10, 2020, 4 replies, in forum: Other health news and research
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