inflammation

  1. leokitten

    The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220254/ Very interesting paper which has identified MYSM1, a part of the ubiquitin system that acts as a molecular switch to deactivate the innate immune system and has the ability to prevent certain diseases caused by an excessive activation of the...
  2. Marco

    Statins, Metformin and Calcium Blockers may help Schizophrenia

    An interesting correlation between use of these medications and reduced symptoms in a large scale study. One proposed mechanism is a reduction in inflammation. Neuroscience News : https://neurosciencenews.com/statins-mental-health-10473/ SMC reaction ...
  3. Sly Saint

    Impaired immune surveillance accelerates accumulation of senescent cells and aging (2018) - Prof. Valery Krizhanovsky and Dr. Yossi Ovadya

    Not sure if this is of any relevance. Impaired immune surveillance accelerates accumulation of senescent cells and aging Yossi Ovadya, Tomer Landsberger, Hanna Leins, Ezra Vadai, Hilah Gal, Anat Biran, Reut Yosef, Adi Sagiv, Amit Agrawal, Alon Shapira, Joseph Windheim, Michael Tsoory, Reinhold...
  4. MeSci

    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    Not sure whether this is really relevant, but the reference to kynurenine looked interesting. NB participants include some dodgy people, e.g. Trudie Chalder. Source: University of Essex (or Sussex?) Date: November 29, 2018 URL: http://sro.sussex.ac.uk/80506/ Persistent fatigue induced by...
    • MeSci
    • Thread
    • bps chalder inflammation interferon interferon-alpha kynurenine me/cfs meruk pariante psychoneuroimmunology
    • Replies: 460
    • Forum: ME/CFS research
  5. Andy

    Low omega-3 index and polyunsaturated fatty acid status in patients with CFS/ME, 2018, Castro-Marerro et al

    Paywalled at https://www.plefa.com/article/S0952-3278(18)30053-X/fulltext
    • Andy
    • Thread
    • 2018 biomarker castro-marrero inflammation me/cfs omega-3 index paper polyunsaturated fatty acids
    • Replies: 9
    • Forum: ME/CFS research
  6. A

    Pentose Phosphate Pathway abd inflammation

    This may be interesting for some given the changes in metabolism . Tagging @mariovitali re LXR role https://www.cell.com/cell-reports/fulltext/S2211-1247(18)31696-6#.W_Qs9gPOjZg.twitter
  7. Andy

    Recognizing leaky gut as a trans-diagnostic target for neuro-immune disorders using clinical chemistry & molecular immunology assays, 2018, Simeonova

    Abstract ahead of print, http://www.eurekaselect.com/167390/article
  8. Andy

    Intestinal barrier dysfunction orchestrates onset of inflammatory host–microbiome cross-talk in a human gut inflammation-on-a-chip, 2018, Shin and Kim

    Paywalled at http://www.pnas.org/content/early/2018/10/18/1810819115 Blog from Jackson Labs about the study https://jaxmecfs.com/2018/11/01/gut-on-a-chip-system-shows-intestinal-epithelial-barrier-disruption-initiates-gut-inflammation/
  9. Andy

    Parkin and PINK1 mitigate STING-induced inflammation, 2018, Youle et al

    Paywalled at https://www.nature.com/articles/s41586-018-0448-9 Article from Nature about this study https://www.nature.com/articles/d41586-018-05988-z
  10. Andy

    Impact of Edible Cricket Consumption on Gut Microbiota in Healthy Adults, a Double-blind, Randomized Crossover Trial, 2018, Stull, Weir et al

    Initially I looked at this for the amusement factor but improved gut health and lower inflammation might be of interest. Open access at https://www.nature.com/articles/s41598-018-29032-2
  11. Andy

    Nature: Newly made mitochondrial DNA drives inflammation

    https://www.nature.com/articles/d41586-018-05764-z
  12. Lidia

    How does emotional stress lead to inflammation?

    It seems widely accepted that “stress” leads to inflammation. “Stress” in this context is always used to denote emotional stress. How does emotional stress lead to inflammation? Is there evidence of how this pathway works? Thanks in advance.
  13. Indigophoton

    Researchers identify key protein involved in triggering inflammation

    https://medicalxpress.com/news/2018-06-key-protein-involved-triggering-inflammation.amp
  14. Indigophoton

    How the brain plays a role in rheumatoid arthritis inflammation

    I thought this was interesting, particularly given Younger's upcoming study on neuroinflammation in ME, and also for the possibility of a future breakthrough in treatments for RA that could potentially be of relevance to ME. Any thoughts, @Jonathan Edwards? The article...
  15. Andy

    Neuroscience News: Is a Stress Shot on the Horizon?

    Based on mice research but at least sounds interesting. https://neurosciencenews.com/stress-vaccine-9279/
  16. Indigophoton

    Rehabilitating lactate: From poison to cure

    The article, https://phys.org/news/2018-05-lactate-poison.amp The paper, https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30186-4? Full paper here, http://sci-hub.tw/10.1016/j.cmet.2018.03.008
  17. Andy

    The putative role of oxidative stress and inflammation in the pathophysiology of sleep dysfunction across neuropsychiatric disorders, 2018, Carvalho

    Paywalled at https://www.smrv-journal.com/article/S1087-0792(17)30152-1/fulltext
    • Andy
    • Thread
    • 2018 carvalho inflammation me/cfs neurology oxidative stress paper sleep
    • Replies: 2
    • Forum: ME/CFS research
  18. Andy

    Brain inflammatory cascade controlled by gut-derived molecules

    https://www.nature.com/articles/d41586-018-05113-0
  19. Indigophoton

    Study shows yogurt may dampen chronic inflammation linked to multiple diseases

    The article, https://medicalxpress.com/news/2018-05-yogurt-dampen-chronic-inflammation-linked.amp From the Journal of Nutrition paper, https://academic.oup.com/jn/advance-article/doi/10.1093/jn/nxy046/4995046
  20. Indigophoton

    Review Article: Mitochondria: An Organelle of Bacterial Origin Controlling Inflammation, Meyer et al, 2018

    May be of general background interest for some, https://www.frontiersin.org/articles/10.3389/fimmu.2018.00536/full
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