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immunology

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  1. EndME
    Thread

    SARS-CoV-2-specific T cell therapy for severe COVID-19: a randomized phase 1/2 trial, 2023, Yannaki et al

    SARS-CoV-2-specific T cell therapy for severe COVID-19: a randomized phase 1/2 trial Abstract Despite advances, few therapeutics have shown...
    Thread by: EndME, Aug 19, 2023, 0 replies, in forum: Epidemics (including Covid-19, not Long Covid)
  2. Mij
    Thread

    The battle between the innate immune cGAS-STING signaling pathway and human herpesvirus infection, 2023, Ximing Jin et al

    The incidence of human herpesvirus (HHVs) is gradually increasing and has affected a wide range of population. HHVs can result in serious...
    Thread by: Mij, Aug 2, 2023, 0 replies, in forum: Other health news and research
  3. Sly Saint
    Thread

    Review Surveying the Metabolic and Dysfunctional Profiles of T Cells and NK Cells in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 2023, Maya

    Abstract: Millions globally suffer from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The inflammatory symptoms, illness onset,...
    Thread by: Sly Saint, Jul 26, 2023, 0 replies, in forum: ME/CFS research
  4. rvallee
    Thread

    Microglia Transcriptional Profiling in Major Depressive Disorder Shows Inhibition of Cortical Gray Matter Microglia, 2023, Huitinga et al

    Microglia Transcriptional Profiling in Major Depressive Disorder Shows Inhibition of Cortical Gray Matter Microglia...
    Thread by: rvallee, Jul 23, 2023, 1 replies, in forum: 'Conditions related to ME/CFS' news and research
  5. Andy
    Thread

    Review An understanding of the immune dysfunction in susceptible people who develop the post-viral fatigue syndromes ME/CFS and Long Covid, 2023 Walker et al

    Abstract Viral infection in most people results in a transient immune/inflammatory response resulting in elimination of the virus and recovery...
    Thread by: Andy, Jul 15, 2023, 2 replies, in forum: ME/CFS research
  6. EndME
    Thread

    The immunology of long COVID, 2023, Altmann et al

    The immunology of long COVID Abstract Long COVID is the patient-coined term for the disease entity whereby persistent symptoms ensue in a...
    Thread by: EndME, Jul 11, 2023, 12 replies, in forum: Long Covid research
  7. rvallee
    Thread

    Higher immune-related gene expression in major depression is independent of CRP levels: results from the BIODEP study, 2023, Pariante et el

    Higher immune-related gene expression in major depression is independent of CRP levels: results from the BIODEP study...
    Thread by: rvallee, Jun 28, 2023, 1 replies, in forum: Other health news and research
  8. Mij
    Thread

    Neuro-PASC is characterized by enhanced CD4+ and diminished CD8+ T cell responses to SARS-CoV-2 Nucleocapsid protein, 2023, Lavanya Visvabharathy

    Introduction: Many people with long COVID symptoms suffer from debilitating neurologic post-acute sequelae of SARS-CoV-2 infection (Neuro-PASC)....
    Thread by: Mij, May 30, 2023, 1 replies, in forum: Long Covid research
  9. Sly Saint
    Thread

    Tissue injury and leukocyte changes in post-acute sequelae of SARS-CoV-2: review of 2833 post-acute patient outcomes, 2023 Islam et al

    Tissue injury and leukocyte changes in post-acute sequelae of SARS-CoV-2: review of 2833 post-acute patient outcomes per immune dysregulation and...
    Thread by: Sly Saint, Jan 17, 2023, 2 replies, in forum: Long Covid research
  10. Andy
    Thread

    Identifying platelet-derived factors as amplifiers of B. burgdorferi-induced cytokine production, 2022, Kerstholt et al

    Abstract Previous studies have shown that monocytes can be ‘trained’ or tolerized by certain stimuli to respond stronger or weaker to a secondary...
    Thread by: Andy, Aug 25, 2022, 0 replies, in forum: 'Conditions related to ME/CFS' news and research
  11. Hutan
    Thread

    MYB orchestrates T cell exhaustion and response to checkpoint inhibition, Tsui, 2022

    https://www.nature.com/articles/s41586-022-05105-1 Abstract CD8+ T cells that respond to chronic viral infections or cancer are characterized by...
    Thread by: Hutan, Aug 18, 2022, 3 replies, in forum: Other health news and research
  12. SNT Gatchaman
    Thread

    Recovering or Persisting: The Immunopathological Features of SARS-CoV-2 Infection in Children, 2022, Buonsenso et al

    Recovering or Persisting: The Immunopathological Features of SARS-CoV-2 Infection in Children Buonsenso D, Valentini P, De Rose C, Tredicine M,...
    Thread by: SNT Gatchaman, Jul 28, 2022, 2 replies, in forum: Long Covid research
  13. rvallee
    Thread

    Unexplained post-acute infection syndromes, 2021, Iwasaki et al

    Full title: Unexplained post-acute infection syndromes Authors: Jan Choutka, Viraj Jansari, Mady Hornig & Akiko Iwasaki Published: Nature, 18 May...
    Thread by: rvallee, May 18, 2022, 27 replies, in forum: 'Conditions related to ME/CFS' news and research
  14. rvallee
    Thread

    Reduced Cell Surface Levels of C-C Chemokine Receptor 5 and Immunosuppression in Long Coronavirus Disease 2019 Syndrome, 2022, Yang et al

    In an exploratory trial treating “long COVID” with the CCR5-binding antibody leronlimab, we observed significantly increased blood cell surface...
    Thread by: rvallee, Apr 22, 2022, 8 replies, in forum: Long Covid research
  15. Wyva
    Thread

    How mycobacterium tuberculosis infection could lead to the increasing risks of CFS and the potential immunological effects (...), 2022, Yang et al

    Full title: How mycobacterium tuberculosis infection could lead to the increasing risks of chronic fatigue syndrome and the potential...
    Thread by: Wyva, Feb 22, 2022, 5 replies, in forum: ME/CFS research
  16. Jaybee00
    Thread

    Targeting the Monocytic-Endothelial-Platelet Axis with Maraviroc and Pravastatin as a Therapeutic Option to Treat Long COVID/ Patterson/PP

    Preprint https://www.researchsquare.com/article/rs-1344323/v1 Post-acute sequelae of COVID (PASC), or long COVID, is a multisystem complication...
    Thread by: Jaybee00, Feb 10, 2022, 14 replies, in forum: Long Covid research
  17. Arvo
    Thread

    SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients, 2023, Charvet et al.

    :emoji_warning: At this point it's still a preprint. Abstract: Patients with COVID-19 may develop abnormal inflammatory response and lymphopenia,...
    Thread by: Arvo, Feb 10, 2022, 6 replies, in forum: Long Covid research
  18. Andy
    Thread

    Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease, 2021, Emy et al

    In mice. Highlights Altered metabolic features of microglia in the absence of host microbiota Bacteria-derived acetate modulates metabolic...
    Thread by: Andy, Dec 3, 2021, 0 replies, in forum: Other health news and research
  19. ola_cohn
    Thread

    A Short Corticosteroid Course Reduces Symptoms and Immunological Alterations Underlying Long-COVID, 2021, Utrero-Rico et al

    Abstract Despite the growing number of patients with persistent symptoms after acute SARS-CoV-2 infection, the pathophysiology underlying...
    Thread by: ola_cohn, Nov 29, 2021, 8 replies, in forum: Long Covid research
  20. Trish
    Thread

    Insular cortex neurons encode and retrieve specific immune responses, 2021, Tamar Koren et al.

    https://www.cell.com/cell/pdf/S0092-8674(21)01223-X.pdf Research done in mice. Highlights Neuronal ensembles in the InsCtx are activated during...
    Thread by: Trish, Nov 10, 2021, 15 replies, in forum: Other health news and research
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