cerebral blood flow

Oxygen tension–mediated erythrocyte membrane interactions regulate cerebral capillary hyperemia Sitong Zhou; Michael Giannetto; James DeCourcey; Hongyi Kang; Ning Kang; Yizeng Li; Suilan Zheng; Hetince Zhao; William R. Simmons; Helen S. Wei; David M. Bodine; Philip S. Low; Maiken Nedergaard...

Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation Helen Shinru Wei; Hongyi Kang; Izad-Yar Daniel Rasheed; Sitong Zhou; Nanhong Lou; Anna Gershteyn; Evan Daniel McConnell; Yixuan Wang; Kristopher Emil Richardson; Andre Francis Palmer; Chris Xu; Jiandi Wan; Maiken...

https://www.mdpi.com/1648-9144/59/12/2153 Worsening Symptoms Is Associated with Larger Cerebral Blood Flow Abnormalities during Tilt-Testing in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) by C. (Linda) M. C. van Campen 1,*, Peter C. Rowe 2 and Frans C. Visser 1 1 Stichting...

Blood-brain barrier breakdown in COVID-19 ICU survivors: an MRI pilot study Wen Shi; Dengrong Jiang; Hannah Rando; Shivalika Khanduja; Zixuan Lin; Kaisha Hazel; George Pottanat; Ebony Jones; Cuimei Xu; Doris Lin; Sevil Yasar; Sung-Min Cho; Hanzhang Lu Objectives Coronavirus disease 2019...

Influence of end-tidal CO2 on cerebral blood flow during orthostatic stress in controls and adults with myalgic encephalomyelitis/chronic fatigue syndrome C. (Linda) M. C. van Campen; Peter C. Rowe; Freek W. A. Verheugt; Frans C. Visser Brain perfusion is sensitive to changes in CO2 levels (CO2...

Introduction: During a standard 70-degree head-up tilt test, 90% of adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) develop an abnormal reduction in cerebral blood flow (CBF). A 70-degree test might not be tolerated by young ME/CFS patients because of the high incidence...

No info https://www.sciencedirect.com/science/article/abs/pii/S2405500X23000907?via=ihub A research letter: https://www.jacc.org/doi/10.1016/j.jacep.2023.02.002 ****** link to post with open access link Two threads on the topic have been merged

Abstract Background Neurological symptoms associated with coronavirus disease 2019 (COVID-19), such as fatigue and smell/taste changes, persist beyond infection. However, little is known of brain physiology in the post-COVID-19 timeframe. Purpose To determine whether adults who experienced...

authors van Campen, Frank Visser Abstract Background: Postural orthostatic tachycardia syndrome (POTS) has been described early after the onset of the COVID-19 infection, but also orthostatic hypotension (OH). In the present study, we hypothesized that orthostatic intolerance decreases over...

Full title: Multimodal MRI of myalgic encephalomyelitis/chronic fatigue syndrome: A cross-sectional neuroimaging study toward its neuropathophysiology and diagnosis Introduction: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), is a debilitating illness affecting up to 24 million...

Background The physiology underlying "brain fog" in the absence of orthostatic stress in postural tachycardia syndrome (POTS) remains poorly understood. Methods and Results We evaluated cognitive and hemodynamic responses (cardiovascular and cerebral: heart rate, blood pressure, end‐tidal...

My summary In CFS subjects, phenylephrine reduces the decrease in cerebral blood flow that occurs during head up tilt testing. This had a positive impact on performance in a cognitive test. The study might hint at how to treat ME/CFS and at the underlying mechanisms of reduced cerebral blood...

Background: Orthostatic intolerance (OI) is a core finding in individuals with myalgic encephalomyelitis /chronic fatigue syndrome (ME/CFS). Deconditioning is often proposed as an important determinant for OI. Deconditioning can be objectively classified using the predicted peak oxygen...

https://osf.io/ef3n4/ The newsbrief posting reminded me that this paper wasn't mentioned. I think it may be a pretty important hypothesis for ME's root cause. It fits what I believe is the root cause of ME: that neuroglia are involved. I'm not sure whether there are any ME symptoms that...

Abstract Background and objectives: Orthostatic intolerance (OI) is a clinical condition in which symptoms worsen upon assuming and maintaining upright posture and are ameliorated by recumbency. OI has a high prevalence in patients with myalgic encephalomyelitis/chronic fatigue syndrome...

Original title: Submaximal Exercise Provokes Increased Activation of the Anterior Default Mode Network During the Resting State as a Biomarker of Postexertional Malaise in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Rakib U. Rayhan et al Abstract Background: Myalgic...

Compression Stockings Improve Cardiac Output and Cerebral Blood Flow during Tilt Testing in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Patients: A Randomized Crossover Trial Abstract Background and Objectives: Orthostatic intolerance (OI) is a clinical condition in which...

Orthostatic Symptoms and Reductions in Cerebral Blood Flow in Long-Haul COVID-19 Patients: Similarities with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Abstract Background and Objectives: Symptoms and hemodynamic findings during orthostatic stress have been reported in both long-haul...

Full title: Cerebral Perfusion and Sensory Testing Results Differ in Interstitial Cystitis/Bladder Pain Syndrome Patients with and without Fibromyalgia: A Site-Specific MAPP Network Study Abstract Purpose: Fibromyalgia is a common co-morbidity in patients with interstitial cystitis/bladder...

I seem to recall Hip, Cort Johnson and others taking sodium bicarbonate before exercise to help reduce PEM? Sodium bicarbonate ingestion mitigates the heat-induced hyperventilation and reduction in cerebral blood velocity during exercise in heat, 2021, Akira Katagiri et al NEW & NOTEWORTHY...