bias

  1. ME/CFS Skeptic

    Cognitive behavioral therapy for treatment of chronic primary insomnia: a randomized controlled trial, 2001, Edinger et al.

    (Note that this is an old trial from 2001) Abstract Context: Use of nonpharmacological behavioral therapy has been suggested for treatment of chronic primary insomnia, but well-blinded, placebo-controlled trials demonstrating effective behavioral therapy for sleep-maintenance insomnia are...
  2. ME/CFS Skeptic

    Interventions that manipulate how patients report symptoms as a separate form of bias

    When we discuss the problems with trials on cognitive behavioral therapy (CBT) and graded exercise therapy (GET) we usually mention things like lack of blinding + subjective outcomes or the lack of a credible control group etc. These are methodological weaknesses that are generally regarded as...
  3. Woolie

    The pervasive problem with placebos in psychology: Why active control groups are not sufficient..., 2013, Boot et al.

    Full reference: Boot, W. R., Simons, D. J., Stothart, C., & Stutts, C. (2013). The pervasive problem with placebos in psychology: Why active control groups are not sufficient to rule out placebo effects. Perspectives on Psychological Science, 8(4), 445-454. Link to fulltext...
  4. Woolie

    Double-Blinding and Bias in Medication and Cognitive-Behavioral Therapy Trials for Major Depressive Disorder, 2015, Berger

    Full reference: Berger, D. (2015). Double-blinding and bias in medication and cognitive-behavioral therapy trials for major depressive disorder. F1000Research, 4. Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732552/ Abstract:
  5. Sean

    Gender biases in estimation of others’ pain, 2021, Zhang L et al

    Highlights • In two studies, perceivers under-estimated female patients’ pain compared with males’ pain. • Perceivers’ pain-related gender stereotypes predicted pain estimation biases. • Perceivers prescribed more psychotherapy for female and more pain medicine for male patients. Abstract...
  6. ME/CFS Skeptic

    Finasteride 5 mg and sexual side effects: how many of these are related to a nocebo phenomenon? by Mondaini et al. 2007

    Abstract Introduction: Sexual adverse experiences such as erectile dysfunction (ED), loss of libido, and ejaculation disorders have been consistent side effects of finasteride in a maximum percentage of 15% after 1 year of therapy. Such data could be seen as far from reality, if compared to a...
  7. rvallee

    Outcome Reporting bias in Exercise Oncology trials (OREO): a cross-sectional study, 2021, Singh, Twomey et al

    Background Despite evidence of selective outcome reporting across multiple disciplines, this has not yet been assessed in trials studying the effects of exercise in people with cancer. Therefore, the purpose of our study was to explore prospectively registered randomised controlled trials (RCTs)...
  8. Kalliope

    Articles by David F Marks

    "Treatment harms to patients with ME/CFS" Quote: - Despite evidence of physiological and cellular abnormalities in myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS), the dominant therapeutic approach has been cognitive behaviour therapy (CBT) and graded exercise therapy (GET)...
  9. Woolie

    When is lack of scientific integrity a reason for retracting a paper? A case study.(2020) Fiedorowicz et al. (about homeopathy for CFS)

    When is lack of scientific integrity a reason for retracting a paper? A case study. Abstract: This editorial has just come out in the Journal of Psychosomatic Research. It is a discussion of issues that arose from this 2004 publication: This study is a triple-blinded randomised controlled...
    • Woolie
    • Thread
    • bias blinding bps fiedorowicz homeopathy me/cfs misconduct rct research methodology researcher allegiance retraction subjective outcomes
    • Replies: 28
    • Forum: Research methodology news and research
  10. Andy

    Bias caused by reliance on patient-reported outcome measures in non-blinded randomized trials: an in-depth look at exercise therapy for CFS, 2020,Tack

    Paywall, https://www.tandfonline.com/doi/full/10.1080/21641846.2020.1848262 Sci hub. no access at time of posting. ETA: Corrected access details.
  11. spinoza577

    How scientists can avoid cognitive bias, video by physicist Sabine Hossenfelder

    (I hope this is the right forum) Sabine Hossenfelder is a physicist who has mad some mostly short and clear videos on physics. She generally takes a critical view. At least recently she was working at the university in Stockholm. Here she talks about problems within science. What she says may...
  12. ME/CFS Skeptic

    My comments to the Cochrane review

    I plan to submit these comments to the current version of the Cochrane review next week (sorry I took me so long to write these down - long story). I thought it might be useful to post it here on S4ME first in case someone notices any mistakes so that I can still correct these before formally...
  13. J

    Implications of ideological bias in social psychology on clinical practice (2020) Silander et al

    https://onlinelibrary.wiley.com/doi/abs/10.1111/cpsp.12312
  14. Sly Saint

    Risk of bias tools in systematic reviews of health interventions: an analysis of PROSPERO-registered protocols - Farrah,Young,Tunis,Zhao Nov 2019

    full paper here https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-019-1172-8
  15. InitialConditions

    Variability in the analysis of a single neuroimaging dataset by many teams, 2019, Botvinik-Nezer et al

    I have just seen this new paper on Twitter. A timely reminder that imaging and the subsequent analysis is not an exact science. https://www.biorxiv.org/content/10.1101/843193v1 Abstract Data analysis workflows in many scientific domains have become increasingly complex and flexible. To assess...
  16. Andy

    The strong focus on positive results in abstracts may cause bias in systematic reviews: a case study on abstract reporting bias, 2019, Duyx et al

    Open access, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637611/
  17. ME/CFS Skeptic

    Bias due to a lack of blinding: a discussion

    I would like to use this thread for a discussion on the effects of a lack of blinding in randomized trials, something that frequently comes up in our discussions elsewhere on the forum. Ever since the new risk of bias (RoB 2) tool for Cochrane came out I’ve been trying to learn more about...
  18. Sly Saint

    Researcher allegiance in research on psychosocial interventions: meta- research study protocol and pilot study - Yoder et al (2019)

    from Introduction interesting, a nice twist perhaps(?) But will anyone use it? Cochrane seem to be going in the opposite direction. full paper here https://bmjopen.bmj.com/content/bmjopen/9/2/e024622.full.pdf
  19. ME/CFS Skeptic

    RoB 2: a revised tool for assessing risk of bias in randomised trials (2019) Sterne et al.

    https://www.bmj.com/content/366/bmj.l4898.full?ijkey=gzAdEdyR713TWzf&keytype=ref
  20. Rick Sanchez

    Bias in medicine - Sex and Race John Oliver

    Thought this would be relevant to many ME/CFS patients. Glad this sort of stuff is getting more mainstream coverage.
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