Abstract: Principal component analysis (PCA) is widely used to control for population structure in genome-wide association studies (GWAS). Top...
This is more of a “my person experience” rant then a high quality discussion as I don’t have the energy for the latter right now, but here goes:...
I don't think we have an open discussion specifically on the problems of bias in academic research. I initially titled this "Bias in science", but...
Emerging Subspecialties in Neurology: Women’s Neurology Hayley F. Thornton,, Sara C. LaHue, Riley Bove, Janet Waters, Mary A. O’Neal, Esther Bui...
Compelling evidence from meta-epidemiological studies demonstrates overestimation of effects in randomized trials that fail to optimize...
Bias, misleading information and lack of respect for alternative views have distorted perceptions of myalgic encephalomyelitis/chronic fatigue...
Catalogue of Bias About Bias enters health studies at all stages and often influences the magnitude and direction of results. To obtain the...
Peters, S., Wearden, A., Morriss, R. et al. Challenges of nurse delivery of psychological interventions for long-term conditions in primary care:...
Bias was reduced in an open-label trial through the removal of subjective elements from the outcome definition Objective: To determine whether...
Abstract Background Cognitive behavioral therapy (CBT) is an evidence-based intervention for severe fatigue. Changes in patients’ fatigue scores...
Abstract Objectives The aim of the study was to analyze adequacy of risk of bias (RoB) judgments for selective reporting in Cochrane systematic...
This is an interesting editorial in the European Journal of Hospital Pharmacy: "Red for danger in systematic reviews?" by Andrew Moore The full...
They have no idea how deep this goes. Small study hints that interference from bodies funding research into public-health issues such as...
This 2007 study from the Journal of Psychosomatic Research to my mind suggests that retrospective subjective symptom reporting in MUS is useless....
Abstract The hypothesis of a Hierarchy of the Sciences with physical sciences at the top, social sciences at the bottom, and biological sciences...
Abstract Background: Patient-reported outcome measures (PROMs) are influenced by psychosocial factors, but it is unknown whether we can influence...
(This is a reference to the discussion on bias due to a lack of blinding here.) Bull, L. (2007). Sunflower therapy for children with specific...
Abstract Control conditions are the primary methodology used to reduce threats to internal validity in randomized controlled trials (RCTs). This...
(Note that this is an old trial from 2001) Abstract Context: Use of nonpharmacological behavioral therapy has been suggested for treatment of...
When we discuss the problems with trials on cognitive behavioral therapy (CBT) and graded exercise therapy (GET) we usually mention things like...
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