acetylcholine

  1. SNT Gatchaman

    Review The Role Of Α7 Nicotinic Acetylcholine Receptors In Post-Acute Sequelae Of Covid-19, 2024, Skok

    The Role Of Α7 Nicotinic Acetylcholine Receptors In Post-Acute Sequelae Of Covid-19 Skok Post-Acute Sequelae of COVID-19 or Long COVID becomes evident some weeks to months following acute COVID-19. Symptoms include cognitive impairment and varying degrees of memory loss with no definitive...
  2. Hutan

    Autoantibodies against muscarinic cholinergic receptor in chronic fatigue syndrome, 2003, Tanaka et al

    An old study that has been included in a list of studies finding issues with G protein-coupled receptors. https://pubmed.ncbi.nlm.nih.gov/12851722/. Paywall Abstract The disturbance of the central nervous system and immunological abnormalities have been suggested in patients with chronic...
    • Hutan
    • Thread
    • acetylcholine autoantibodies chrm1 gpcr
    • Replies: 10
    • Forum: ME/CFS research
  3. Andy

    Cholinergic regulation of vascular endothelial function by human ChAT+ T cells 2023 Tarnawski et al

    Significance ACh-releasing choline acetyltransferase (ChAT)+ T cells promote vasodilation and regulate blood pressure in mice, but human ChAT+ T cells and the molecular mechanisms by which ChAT-expression is regulated remain undefined. In this study, we identify primary ChAT+ T cells in patients...
  4. Hutan

    Anti-ganglionic acetylcholine receptor antibodies in functional neurological symptom disorder/conversion disorder, 2023, Nagata et al

    https://www.frontiersin.org/articles/10.3389/fneur.2023.1137958/full Open access Team from Kagoshima, Japan Objective: Autoimmune autonomic ganglionopathy (AAG) is a rare disorder characterized by autonomic failure associated with the presence of anti-ganglionic acetylcholine receptor (gAChR)...
  5. Mij

    Is the post-COVID-19 syndrome a severe impairment of acetylcholine-orchestrated neuromodulation that responds to nicotine administration?

    Marco Leitzke, 2023 Abstract Following a SARS-CoV-2 infection, many individuals suffer from post-COVID-19 syndrome. It makes them unable to proceed with common everyday activities due to weakness, memory lapses, pain, dyspnea and other unspecific physical complaints. Several investigators...
  6. SNT Gatchaman

    Biomarkers in the diagnostic algorithm of myalgic encephalomyelitis/chronic fatigue syndrome, 2022, Gravelsina et al

    Biomarkers in the diagnostic algorithm of myalgic encephalomyelitis/chronic fatigue syndrome Gravelsina Sabine, Vilmane Anda, Svirskis Simons, Rasa-Dzelzkaleja Santa, Nora-Krukle Zaiga, Vecvagare Katrine, Krumina Angelika, Leineman Iana, Shoenfeld Yehuda, Murovska Modra Myalgic...
    • SNT Gatchaman
    • Thread
    • acetylcholine adrenergic receptors antibodies biomarker hhv-6 hhv-6 pcr muscarine receptors
    • Replies: 11
    • Forum: ME/CFS research
  7. Sly Saint

    Neurovascular Dysregulation and Acute Exercise Intolerance in ME/CFS: A Randomized, Placebo-Controlled Trial of Pyridostigmine, 2022, Systrom et al

    ABSTRACT Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by intractable fatigue, post-exertional malaise, and orthostatic intolerance, but its pathophysiology is poorly understood. Pharmacologic cholinergic stimulation was used to test the hypothesis that...
    • Sly Saint
    • Thread
    • acetylcholine exercise physiology mestinon pyridostigmine systrom treatment
    • Replies: 33
    • Forum: ME/CFS research
  8. Hoopoe

    Decreased NO production in endothelial cells exposed to plasma from ME/CFS patients, Bertinat et al (2022)

    Decreased NO production in endothelial cells exposed to plasma from ME/CFS patients Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease characterized by severe and persistent fatigue. Along with clinical studies showing endothelial dysfunction (ED) in a...
    • Hoopoe
    • Thread
    • acetylcholine endothelial function endothelium micro-rna nitric oxide something in the blood
    • Replies: 69
    • Forum: ME/CFS research
  9. Andy

    Association of autoantibodies to muscarinic acetylcholine receptors with gastrointestinal symptoms and disease severity in [pwPOTS], 2022,Sunami et al

    Full title: Association of autoantibodies to muscarinic acetylcholine receptors with gastrointestinal symptoms and disease severity in patients with postural orthostatic tachycardia syndrome Abstract Previous studies have reported a relationship between postural orthostatic tachycardia...
  10. V

    Ganglionic Acetylcholine Receptor Antibodies in Postural Tachycardia Syndrome. Bryarly et al. 8/2021

    https://pubmed.ncbi.nlm.nih.gov/34484936/ Abstract Objective: Postural tachycardia syndrome (POTS), the most common form of dysautonomia, may be associated with autoimmunity in some cases. Autoantibodies against the ganglionic acetylcholine receptor (gAChR) have been reported in a minority of...
  11. ME/CFS Skeptic

    Effect of Galantamine Hydrobromide in Chronic Fatigue Syndrome A Randomized Controlled Trial, 2004, Blacker et al.

    (Note that this is an old study from 2004) Abstract Context: There is no established pharmacological treatment for the core symptoms of chronic fatigue syndrome (CFS). Galantamine hydrobromide, an acetyl cholesterone inhibitor, has pharmacological properties that might benefit patients with...
    • ME/CFS Skeptic
    • Thread
    • 2004 acetylcholine blacker cholinesterase cognitive dysfunction cortisol galantamine me/cfs paper treatment
    • Replies: 8
    • Forum: ME/CFS research
  12. Suffolkres

    Gulf War Illness - causes

    =AT25vxMZOC9yc2g7Plhs8S0Nodsy-Nbl5GfAPCIfkD5f_4dp1UvDI1FrEMp0re0Q6-UOr-hZgSynCHGySnIJ1ZILhDkUBnu8tTnApZnMYyfKVA4Kreex68tDR1ntF4S1F2VrfYqXVzNX6jW9SSQrVz_bkds']https://www.dailymail.co.uk/.../Gulf-War-syndrome-not... Gulf War syndrome which left 250,000 veterans suffering long-term fatigue and...
    • Suffolkres
    • Thread
    • acetylcholine aetiology antibiotics cholinesterase ciprofloxacin discussion thread fluoroquinolones gulf war illness gwi iraq iraq war
    • Replies: 68
    • Forum: Gulf War Illness
  13. L

    neurotoxin1 (endogenous)

    https://www.cell.com/neuron/fulltext/S0896-6273(11)00254-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627311002546%3Fshowall%3Dtrue This review discusses three emerging hypotheses about ways that the nicotinic system can be modulated. First is the role played by...
  14. L

    Alpha-7 nicotinic acetylcholine receptor literature

    Alpha7 Nicotinic Receptors as Therapeutic Targets in Schizophrenia Jason R Tregellas, PhD, Korey P Wylie, MD https://academic.oup.com/ntr/article/21/3/349/5078145 The role of a recently discovered Alpha-7 nicotinic acetylcholine receptor on amyloid-beta pathology in Alzheimer's disease...
  15. Andy

    Intestinal Epithelial Wnt Signaling Mediates Acetylcholine-Triggered Host Defense against Infection, 2018, Irazoqui et al

    Paywalled at https://www.cell.com/immunity/fulltext/S1074-7613(18)30186-9
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