Andy
Retired committee member
Ramsay 2018 award recipient
https://solvecfs.org/ramsay-2018-meet-professor-theoharis-theoharides-md-phd/“Extracellular vesicles fom ME/CFS Patients and their effect on human mast cells and microglia mediators secretion”
A project summary as written by Professor Theoharis Theoharides, MD, PhD
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) affects about 1-2% of the US population with a 4 to 1, female to male ratio, and is characterized by debilitating fatigue of six months in the absence of systemic diseases. Many ME/CFS patients also have Fibromyalgia Syndrome (FMS), Mast Cell Activation Syndrome (MCAS), Pelvic Bladder Syndrome/Interstitial Cystitis (PBS/IC) and Irritable Bowel Syndrome (IBS), which worsen with stress. Unfortunately, ME/CFS pathogenesis remains unknown and there are no objective biomarkers making accurate diagnosis, prognosis and effective treatment difficult.