International Journal of Qualitative Studies on Health and Wellbeing Patient's experiences and effects of non-pharmacological treatment for myalgic encephalomyelitis/chronic fatigue syndrome - Anne Marit Mengshoel, Ingrid B. Helland, Mira Meeu, Jesus Castro-Marrero, Derek Pheby & Elin Bolle Strand Results Effect studies addressed cognitive behavioural therapy (CBT, n = 4), multimodal rehabilitation (n = 2) and activity-pacing (n = 2). CBT reduced fatigue scores more than usual care or waiting list controls. The effects of rehabilitation and activity-pacing were inconsistent. The contents, assessment methods and effects of rehabilitation and activity pacing studies varied. For patients, health professionals’ recognition of ME/CFS and support were crucial, but they expressed ambiguous experiences of what the NPTs entail. Conclusions Methodological differences make comparisons across NPTs impossible, and from a patient perspective the relevance of the specific contents of NPTs are unclear. Future well-designed studies should focus on developing NPTs tailored to patients’ concerns and evaluation tools reflecting what is essential for patients.