Full title: Effects of l-Arginine Plus Vitamin C Supplementation on Physical Performance, Endothelial Function, and Persistent Fatigue in Adults with Long COVID: A Single-Blind Randomized Controlled Trial
Abstract
Long COVID, a condition characterized by symptom and/or sign persistence...
I really wonder how Drs in can give prescriptions for Oramoph and Tramadol but not medical marijuana....
Does anyone have any thoughts?
https://www.independent.co.uk/life-style/health-and-families/multiple-sclerosis-symptoms-hereditary-cause-b2239253.html
Financial Times article:
Blood clot drug totally ineffective as post-Covid treatment, research finds
Results from UK-wide trials on anticoagulant Apixaban set to change protocols around the world
A drug to reduce blood clots, widely prescribed to Covid-19 patients after discharge from hospital...
http://www.geneuro.com/fr/patients-fr/francais
The GNC-501 study, titled “Temelimab as a Disease Modifying Therapy in Patients with Neurological, Neuropsychological, and Psychiatric Symptoms in Post-COVID-19 or Post-Acute Sequelae of COVID-19 (PASC) Syndrome,” will enroll 200 patients from...
Highlights
• Although non-pharmacological interventions are recommended as first-line treatment for fibromyalgia, there are currently no evidence-based recommendations as to which intervention(s) to offer as core and adjunctive treatments for each common symptom in fibromyalgia.
• This Delphi...
Objectives: This meta-analysis aimed to assess the effectiveness and safety of Chinese herbal medicine (CHM) in treating chronic fatigue syndrome (CFS).
Methods: Nine electronic databases were searched from inception to May 2022. Two reviewers screened studies, extracted the data, and assessed...
A continual increase in cases of Long Covid constitutes a medical and socioeconomic challenge to health systems around the globe. While the true extent of this problem cannot yet be fully evaluated, recent data suggests that up to 20% of people with confirmed with SARS-CoV-2 suffer from...
Abstract
The causes of depression are diverse and are still not fully understood. Recently, an increasing role is attributed to nutritional and inflammatory factors. The aim of this study was to evaluate selected metabolites of the tryptophan kynurenine pathway in depressive patients with small...
A drug company called Ashvattha Therapeutics is working on a new drug candidate for long Covid, OP-101.
Link: Ashvattha previews plans for long Covid trial in mid-2023
Key takeaways:
OP-101 was originally developed for neurodegenerative disease
They're discussing their plans with the FDA so...
Abstract
Context.— Chronic fatigue syndrome (CFS) is associated with a dysregulated hypothalamic–pituitary adrenal axis and hypocortisolemia.
Objective.— To evaluate the efficacy and safety of low-dose oral hydrocortisone as a treatment for CFS.
Design.— A randomized, placebo-controlled...
Preprint and final publication threads merged
Final publication abstract further down the thread here
Abstract
Background: Post COVID-19 condition (PCC) is defined as symptoms lasting more than 12 weeks after developing COVID-19. Evidence of mitochondrial dysfunction has been reported in...
Summary
Orthostatic hypotension is an unusually large decrease in blood pressure on standing that increases the risk of adverse outcomes even when asymptomatic. Improvements in haemodynamic profiling with continuous blood pressure measurements have uncovered four major subtypes: initial...
Review
pdf
Question(s)
Is exercise helpful in individuals with long COVID?
Is post-exertional symptom exacerbation a risk in long COVID?
https://aci.health.nsw.gov.au/__data/assets/pdf_file/0010/735562/Evidence-Check-Exercise-and-long-COVID.pdf
Full title: What psychological interventions are effective for the management of persistent physical symptoms (PPS)? A systematic review and meta-analysis
Abstract
Objectives
Presentation of persistent physical symptoms is associated with increased health care utilization, yet clinical...
[This seems to be only very tenuously about ME/CFS]
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease of unknown etiology and without effective treatment options. The onset of ME/CFS is often associated with neuroinflammation following bacterial or...
Abstract
Objective
Long COVID affects approximately ten-percent of people following post-acute Coronavirus infection. Long COVID is a complex, multisystemic recent illness. Therefore, there are currently no unitary guidelines on its management. The UK national guidelines currently recommended...
Abstract
Post-COVID-19 condition refers to a range of persisting physical, neurocognitive, and neuropsychological symptoms after SARS-CoV-2 infection. The mechanism can be related to brain tissue pathology caused by virus invasion or indirectly by neuroinflammation and hypercoagulability. This...
https://www.tandfonline.com/doi/abs/10.1080/03007995.2022.2096351
This study aimed to describe the neurological improvements in a patient with severe long COVID brain dysfunction following perispinal etanercept administration. Perispinal administration of etanercept, a novel method designed to...
Abstract
Activation of innate immunity and deposition of blood-derived fibrin in the central nervous system (CNS) occur in autoimmune and neurodegenerative diseases, including multiple sclerosis (MS) and Alzheimer’s disease (AD). However, the mechanisms that link disruption of the blood–brain...
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