treatment

A significant subset (NIH CPET study estimated at 25%) of people with ME experience a phenomenon colloquially described as an “adrenaline rush” during and after overexertion, but before PEM begins. This is characterised by a rush of “fake energy” giving symptoms such as tatycardia, muscle...

Given this recommendation for the use of metformin for people with Post Covid Condition who get a new Covid-19 infection, I thought it was worth having a discussion thread for it in the Treatment section. Relevant research threads can be found by clicking on the metformin tag, top left.

Hello, As part of my psychology Masters at Oxford Brookes University I'm conducting research into the motivations for complementary and alternative medicine use in those with chronic illness. One of the subcategories I'm particularly looking at are those with ME/CFS. If you're a UK resident...

Not sure if there are many other examples, but Ron Davis mentions one potentially successful case (or could be spontaneous remission) of someone recovering after avoiding crashes for a year: "One researcher had ME and she didn't have a crash and after a year she got better."

Evaluating myelophil, a 30% ethanol extract of Astragalus membranaceus and Salvia miltiorrhiza, for alleviating fatigue in long COVID: a real-world observational study 20 June 2024 Jin-Yong Joung, Jin-Seok Lee, Yujin Choi, Yoon Jung Kim, Hyeon-Muk Oh, Hyun-Sik Seo, Chang-Gue Son Background...

Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection Key Points Question What is the efficacy of 15 days of nirmatrelvir-ritonavir for improving select symptoms of postacute sequelae of SARS-CoV-2 infection (PASC)? Findings This randomized clinical...

Circulating microaggregates as biomarkers for the Post‐COVID syndrome Hermann; Lisch; Gerth; Wick; Fries; Wick CoVID-19 can develop into Post-COVID syndrome of potentially high morbidity, with procoagulation and reactivation of dormant viral infections being hypothesized pathophysiological...

One of my doctors informed me today that this drug has been recently approved by NICE and is going to try me on it for my sleep issues. He said it will help when I feel too wired to get to sleep. Other insomnia sufferers might want to consider speaking to their doctor about it.

https://www.simmaronresearch.com/rapamycin-trial The First Biomarker-Driven Treatment Trial for ME/CFS Subsets Mean Success Until now, the heterogeneity of the patient population and the lack of a reliable biomarker to diagnose and prognose ME/CFS has thwarted clinical trials for both...

Now published - link here ******** Preprint From @MSEsperanza: "The idea of rehabilitation needs to be completely rethought for this disease" A qualitative analysis of patients' experiences with inpatient rehabilitation for long/post COVID, Hammer et al [full text in German only] Abstract...

https://erj.ersjournals.com/content/62/suppl_67/PA4639 Exercise capacity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) treated with long-term pyridostigmine Johanna Squires, Sarra Al-Zayer, David Systrom European Respiratory Journal 2023 62: PA4639; DOI...

A team in Germany is planning to launch a trial with the drug IMU-838 trial for Long Covid. Currently there aren’t too many details on the trial, however Maria Vehreschild of the Universitätsklinikum Frankfurt has given some details in this talk www.vimeo.com/873993707/description (from 32:30...

Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID? Abstract Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID (LC) are characterized by similar immunological alterations, persistence of chronic viral infection...

[Approx 25% of participants had LC] Background Chronic fatigue (CF) is a complex phenomenon without clear etiology that may require long-term treatment, but to date, no specific therapy has been identified for it. Some botanicals might be helpful in the management of CF. Among these botanicals...

'Many patients with neurogenic orthostatic hypotension also have hypertension in the supine position. The BP can be extremely labile, resembling a volatile stock market chart.' Abstract Symptoms of autonomic dysfunction are prevalent and can be very debilitating, reducing the quality of life...

Full title: Semi-supervised exercise training program more effective for individuals with postural orthostatic tachycardia syndrome in randomized controlled trial Abstract Purpose Exercise like any medication requires the correct dose; to be effective the appropriate frequency, duration, and...

https://direct.mit.edu/neco/article-abstract/26/11/2594/7999/Coenzyme-Q10-Benefits-Symptoms-in-Gulf-War?redirectedFrom=fulltext paywall I think Abstract We sought to assess whether coenzyme Q10 (CoQ10) benefits the chronic multisymptom problems that affect one-quarter to one-third of 1990–1...

The Role of Hypothalamic Phospholipid Liposomes in the Supportive Therapy of Some Manifestations of Long Covid: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Brain Fog Abstract Long Covid is a heterogeneous clinical condition in which Myalgic Encephalomyelitis/Chronic...

Why telling pwOI to just drink more water might not be as helpful as you'd think. I feel this Instagram post is worth a read, including the comments.

Abstract Post-infectious fatigue is a common complication that can lead to decreased physical efficiency, depression, and impaired quality of life. Dysbiosis of the gut microbiota has been proposed as a contributing factor, as the gut–brain axis plays an important role in regulating physical...