treatment

  1. SNT Gatchaman

    [Case Report] Circulating microaggregates as biomarkers for the Post‐COVID syndrome, 2024, Hermann et al.

    Circulating microaggregates as biomarkers for the Post‐COVID syndrome Hermann; Lisch; Gerth; Wick; Fries; Wick CoVID-19 can develop into Post-COVID syndrome of potentially high morbidity, with procoagulation and reactivation of dormant viral infections being hypothesized pathophysiological...
  2. Saz94

    Daridorexant - treatment for insomnia

    One of my doctors informed me today that this drug has been recently approved by NICE and is going to try me on it for my sleep issues. He said it will help when I feel too wired to get to sleep. Other insomnia sufferers might want to consider speaking to their doctor about it.
  3. B

    Rapamycin Pilot Treatment Trial for ME/CFS

    https://www.simmaronresearch.com/rapamycin-trial The First Biomarker-Driven Treatment Trial for ME/CFS Subsets Mean Success Until now, the heterogeneity of the patient population and the lack of a reliable biomarker to diagnose and prognose ME/CFS has thwarted clinical trials for both...
  4. Kitty

    "The idea of rehabilitation needs to be completely rethought for this disease" A qualitative analysis of patients' experiences, 2023, Hammer et al

    Now published - link here ******** Preprint From @MSEsperanza: "The idea of rehabilitation needs to be completely rethought for this disease" A qualitative analysis of patients' experiences with inpatient rehabilitation for long/post COVID, Hammer et al [full text in German only] Abstract...
  5. Dolphin

    Trial Report Exercise capacity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) treated with long-term pyridostigmine, 2023, Systrom

    https://erj.ersjournals.com/content/62/suppl_67/PA4639 Exercise capacity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) treated with long-term pyridostigmine Johanna Squires, Sarra Al-Zayer, David Systrom European Respiratory Journal 2023 62: PA4639; DOI...
  6. E

    Disease Modifying Therapy (IMU-838) to be trialled in Long Covid

    A team in Germany is planning to launch a trial with the drug IMU-838 trial for Long Covid. Currently there aren’t too many details on the trial, however Maria Vehreschild of the Universitätsklinikum Frankfurt has given some details in this talk www.vimeo.com/873993707/description (from 32:30...
  7. E

    Review Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID?, 2023, Ruiz-Pablos et al

    Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID? Abstract Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID (LC) are characterized by similar immunological alterations, persistence of chronic viral infection...
  8. Andy

    Two-month period of 500 mg lecithin-based delivery form of quercetin daily dietary supplementation counterbalances CF symptoms: 2023 Rondanelli et al

    [Approx 25% of participants had LC] Background Chronic fatigue (CF) is a complex phenomenon without clear etiology that may require long-term treatment, but to date, no specific therapy has been identified for it. Some botanicals might be helpful in the management of CF. Among these botanicals...
  9. Mij

    Review Non-Pharmacological Treatment of Autonomic Dysfunction in Parkinson’s Disease and Other Synucleinopathies, 2023, Palma, Jose-Albertoa;Thijs, Roland

    'Many patients with neurogenic orthostatic hypotension also have hypertension in the supine position. The BP can be extremely labile, resembling a volatile stock market chart.' Abstract Symptoms of autonomic dysfunction are prevalent and can be very debilitating, reducing the quality of life...
  10. Andy

    Semi-supervised exercise training program more effective for individuals with postural orthostatic tachycardia syndrome... 2023 Wheatley-Guy et al

    Full title: Semi-supervised exercise training program more effective for individuals with postural orthostatic tachycardia syndrome in randomized controlled trial Abstract Purpose Exercise like any medication requires the correct dose; to be effective the appropriate frequency, duration, and...
  11. Hutan

    Coenzyme Q10 Benefits Symptoms in Gulf War Veterans: Results of a Randomized Double-Blind Study, 2014, Golomb et al

    https://direct.mit.edu/neco/article-abstract/26/11/2594/7999/Coenzyme-Q10-Benefits-Symptoms-in-Gulf-War?redirectedFrom=fulltext paywall I think Abstract We sought to assess whether coenzyme Q10 (CoQ10) benefits the chronic multisymptom problems that affect one-quarter to one-third of 1990–1...
  12. Sly Saint

    Hypothesis The Role of Hypothalamic Phospholipid Liposomes in the Supportive Therapy of Some Manifestations of Long Covid: (ME/CFS) and Brain Fog,2023 Menichetti

    The Role of Hypothalamic Phospholipid Liposomes in the Supportive Therapy of Some Manifestations of Long Covid: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Brain Fog Abstract Long Covid is a heterogeneous clinical condition in which Myalgic Encephalomyelitis/Chronic...
  13. mango

    "Drink more water"

    Why telling pwOI to just drink more water might not be as helpful as you'd think. I feel this Instagram post is worth a read, including the comments.
  14. Andy

    Positive Effects of Probiotic Therapy in Patients with Post-Infectious Fatigue, 2023, Obermoser et al

    Abstract Post-infectious fatigue is a common complication that can lead to decreased physical efficiency, depression, and impaired quality of life. Dysbiosis of the gut microbiota has been proposed as a contributing factor, as the gut–brain axis plays an important role in regulating physical...
  15. Mij

    Effects of daily artificial gravity training on orthostatic tolerance following 60-day strict head-down tilt bedrest, 2023, J.-N. Hoenemann et al

    Abstract Purpose Orthostatic intolerance commonly occurs following immobilization or space flight. We hypothesized that daily artificial gravity training through short-arm centrifugation could help to maintain orthostatic tolerance following head-down tilt bedrest, which is an established...
  16. M

    Protocol A Proof-of-concept Study to Evaluate the Efficacy and Safety of Rozanolixizumab to Treat [Adults] With Severe Fibromyalgia Syndrome, 2022-4, UK

    https://classic.clinicaltrials.gov/ct2/show/NCT05643794?recrs=abdf&type=Intr&cond=Fibromyalgia&draw=3&rank=11 Someone is moving ahead with the theory of autoimmune antibodies for fibromyalgia
  17. Sly Saint

    Strawberries Improve Pain and Inflammation in Obese Adults with Radiographic Evidence of Knee Osteoarthritis

    Abstract Osteoarthritis (OA), the most common form of arthritis, is a significant public health burden in U.S. adults. Among its many risk factors, obesity is a key player, causing inflammation, pain, impaired joint function, and reduced quality of life. Dietary polyphenols and other bioactive...
  18. Hutan

    Protocol Phase III Clinical Trial on the Efficacy and Safety of Meplazumab ... in the Treatment of Post-covid-19, 2023

    The actual study start date was March 2023, the estimated primary end date was 1 June 2023 and the estimated study completion date is 1 October 2023. Clinical Trials link: https://clinicaltrials.gov/ct2/show/NCT05813587?term=Meplazumab&draw=2&rank=8 Randomized, double-blind...
  19. Sly Saint

    Fighting Post-COVID and ME/CFS – development of curative therapies, 2023, Scheibenbogen et al

    The sequela of COVID-19 include a broad spectrum of symptoms that fall under the umbrella term post-COVID-19 condition or syndrome (PCS). Immune dysregulation, autoimmunity, endothelial dysfunction, viral persistence, and viral reactivation have been identified as potential mechanisms. However...
  20. SNT Gatchaman

    The effect of hyperbaric oxygen therapy on myocardial function in post-COVID-19 syndrome patients: a randomized controlled trial, 2023, Leitman et al.

    The effect of hyperbaric oxygen therapy on myocardial function in post-COVID-19 syndrome patients: a randomized controlled trial Leitman, Marina; Fuchs, Shmuel; Tyomkin, Vladimir; Hadanny, Amir; Zilberman-Itskovich, Shani; Efrati, Shai Post-COVID-19 condition refers to a range of persisting...
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