Circulating microaggregates as biomarkers for the Post‐COVID syndrome
Hermann; Lisch; Gerth; Wick; Fries; Wick
CoVID-19 can develop into Post-COVID syndrome of potentially high morbidity, with procoagulation and reactivation of dormant viral infections being hypothesized pathophysiological...
One of my doctors informed me today that this drug has been recently approved by NICE and is going to try me on it for my sleep issues. He said it will help when I feel too wired to get to sleep.
Other insomnia sufferers might want to consider speaking to their doctor about it.
https://www.simmaronresearch.com/rapamycin-trial
The First Biomarker-Driven Treatment Trial for ME/CFS
Subsets Mean Success
Until now, the heterogeneity of the patient population and the lack of a reliable biomarker to diagnose and prognose ME/CFS has thwarted clinical trials for both...
Now published - link here
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Preprint
From @MSEsperanza:
"The idea of rehabilitation needs to be completely rethought for this disease" A qualitative analysis of patients' experiences with inpatient rehabilitation for long/post COVID, Hammer et al [full text in German only]
Abstract...
A team in Germany is planning to launch a trial with the drug IMU-838 trial for Long Covid. Currently there aren’t too many details on the trial, however Maria Vehreschild of the Universitätsklinikum Frankfurt has given some details in this talk
www.vimeo.com/873993707/description (from 32:30...
Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID?
Abstract
Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID (LC) are characterized by similar immunological alterations, persistence of chronic viral infection...
[Approx 25% of participants had LC]
Background
Chronic fatigue (CF) is a complex phenomenon without clear etiology that may require long-term treatment, but to date, no specific therapy has been identified for it. Some botanicals might be helpful in the management of CF. Among these botanicals...
'Many patients with neurogenic orthostatic hypotension also have hypertension in the supine position. The BP can be extremely labile, resembling a volatile stock market chart.'
Abstract
Symptoms of autonomic dysfunction are prevalent and can be very debilitating, reducing the quality of life...
Full title: Semi-supervised exercise training program more effective for individuals with postural orthostatic tachycardia syndrome in randomized controlled trial
Abstract
Purpose
Exercise like any medication requires the correct dose; to be effective the appropriate frequency, duration, and...
https://direct.mit.edu/neco/article-abstract/26/11/2594/7999/Coenzyme-Q10-Benefits-Symptoms-in-Gulf-War?redirectedFrom=fulltext
paywall I think
Abstract
We sought to assess whether coenzyme Q10 (CoQ10) benefits the chronic multisymptom problems that affect one-quarter to one-third of 1990–1...
The Role of Hypothalamic Phospholipid Liposomes in the Supportive Therapy of Some Manifestations of Long Covid: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Brain Fog
Abstract
Long Covid is a heterogeneous clinical condition in which Myalgic Encephalomyelitis/Chronic...
Abstract
Post-infectious fatigue is a common complication that can lead to decreased physical efficiency, depression, and impaired quality of life. Dysbiosis of the gut microbiota has been proposed as a contributing factor, as the gut–brain axis plays an important role in regulating physical...
Abstract
Purpose
Orthostatic intolerance commonly occurs following immobilization or space flight. We hypothesized that daily artificial gravity training through short-arm centrifugation could help to maintain orthostatic tolerance following head-down tilt bedrest, which is an established...
https://classic.clinicaltrials.gov/ct2/show/NCT05643794?recrs=abdf&type=Intr&cond=Fibromyalgia&draw=3&rank=11
Someone is moving ahead with the theory of autoimmune antibodies for fibromyalgia
Abstract
Osteoarthritis (OA), the most common form of arthritis, is a significant public health burden in U.S. adults. Among its many risk factors, obesity is a key player, causing inflammation, pain, impaired joint function, and reduced quality of life. Dietary polyphenols and other bioactive...
The actual study start date was March 2023, the estimated primary end date was 1 June 2023 and the estimated study completion date is 1 October 2023.
Clinical Trials link: https://clinicaltrials.gov/ct2/show/NCT05813587?term=Meplazumab&draw=2&rank=8
Randomized, double-blind...
The sequela of COVID-19 include a broad spectrum of symptoms that fall under the umbrella term post-COVID-19 condition or syndrome (PCS). Immune dysregulation, autoimmunity, endothelial dysfunction, viral persistence, and viral reactivation have been identified as potential mechanisms. However...
The effect of hyperbaric oxygen therapy on myocardial function in post-COVID-19 syndrome patients: a randomized controlled trial
Leitman, Marina; Fuchs, Shmuel; Tyomkin, Vladimir; Hadanny, Amir; Zilberman-Itskovich, Shani; Efrati, Shai
Post-COVID-19 condition refers to a range of persisting...
cardiac function
echocardiography
global longitudinal strain
hbot
israel
left ventricular dysfunction
long covid
oxygen
randomized controlled trial
treatment
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