treatment

Post copied from the LC in the media thread

https://www.cochrane.org/CD014682/SYMPT_how-effective-are-antidepressants-used-treat-chronic-pain-and-do-they-cause-unwanted-effects Key messages • We are only confident in the effectiveness of one antidepressant: duloxetine. We found that a standard dose (60 mg) was effective, and that there...

Comparative Cohort Study of Post-Acute Covid-19 Infection with a Nested, Randomized Controlled Trial of Ivabradine for Those With Postural Orthostatic Tachycardia Syndrome (The COVIVA Study) David Saunders; Thomas B Arnold; Jason M Lavendar; Daoqin Bi; Karl Alcover; Lydia D Hellwig; Sahar T...

Efficacy and tolerability of an endogenous metabolic modulator (AXA1125) in fatigue-predominant long COVID: a single-centre, double-blind, randomised controlled phase 2a pilot study Lucy E.M. Finnigan Mark Philip Cassar Margaret James Koziel Joel Pradines Hanan Lamlum Karim Azer et al...

LDN Tlr4 inhibition explanation If LDN works via inhibit glia tlr4, does that mean tlr4 is being activated in the first place? So what was activating? Or can inhibiting tlr4 inhibit the common pathways of other signals? For example il1. Tldr, if glia is activated by il1, can inhibit tlr4...

Background Recent studies have demonstrated that antiadrenergic autoantibodies are involved in the pathophysiology of postural orthostatic tachycardia syndrome (POTS). Objective The purpose of this study was to test the hypothesis that transcutaneous low-level tragus stimulation (LLTS)...

Free fulltext: https://www.mdpi.com/1660-4601/20/4/3477 Non-Pharmacological Therapies for Post-Viral Syndromes, Including Long COVID: A Systematic Review by by Joht Singh Chandan 1,*,Kirsty R. Brown 1,2,Nikita Simms-Williams 1,Nasir Z. Bashir 3,Jenny Camaradou 4,Dominic Heining 5,Grace M...

Full title: Four-year follow-up on fatigue and sleep quality of a three-armed partly randomized controlled study in breast cancer survivors with cancer-related fatigue Abstract Cancer-related fatigue (CRF) is a frequent long-term symptom in non-metastasized breast cancer patients (BC). This...

https://www.frontiersin.org/articles/10.3389/fmed.2023.1122529/full Post-acute sequelae of COVID (PASC), or long COVID, is a multisystem complication of SARS-CoV-2 infection that continues to debilitate millions worldwide thus highlighting the public health importance of identifying effective...

The Draft Report by the Institute for Quality and Efficiency in Healthcare Does Not Provide Any Evidence That Graded Exercise Therapy and Cognitive Behavioral Therapy Are Safe and Effective Treatments for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome by Mark Vink and Alexandra Vink-Niese...

American Cryosystem Corporation is running a trial "Treatment of Long COVID Utilizing Autologous Stem Cells" The details are here on Clinical Trials. Both the treatment arm and the placebo arm will have fat cells removed by liposuction. Later the treatment arm will have 150 million cells of...

Summary: Diphenylbutylpiperidines (DPBPs), a older class of antipsychotic medications can effectively be repurposed to help treat type 2 diabetes, a new study reports. The mechanism Ussher and his team turned their attention to is succinyl CoA:3-ketoacid CoA transferase (SCOT), an enzyme...

Temelimab #3, l'évolution de mon état après 2 injections Translation: Temelimab #3, the evolution of my condition after 2 injections

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489802/ Open access Abstract Fibromyalgia (FM) is a complex, multi-symptom condition that predominantly affects women. The majority of those affected are unlikely to gain significant symptomatic control from the few treatments that are approved for...

https://link.springer.com/article/10.1007/s10067-014-2517-2 Open access Abstract Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that...

https://clinicaltrials.gov/ct2/show/study/NCT05633407?term=efgartigimod&cond=POTS+-+Postural+Orthostatic+Tachycardia+Syndrome&draw=2&rank

The purpose of this study was to look at the effects of low and high intensity resistance training (RT) on the mood states of fibromyalgia patients (FM). A total of 69 women participated in the study, with 31 healthy women serving as control group (HC), and 28 women diagnosed with FM being...

Free full text: https://www.dovepress.com/pots-and-pregnancy-a-review-of-literature-and-recommendations-for-eval-peer-reviewed-fulltext-article-IJWH REVIEW POTS and Pregnancy: A Review of Literature and Recommendations for Evaluation and Treatment Authors Morgan K , Smith A, Blitshteyn S...

Abstract (1) Background: Telerehabilitation allows health professionals to monitor patients without face-to-face contact. The objective was to analyze the effects of a telerehabilitation program based on aerobic exercise in women with fibromyalgia at 6-month follow-up. (2) Methods...

Abstract Background Wasabi (Eutrema japonicum) is a common pungent spice used in Japan. 6-Methylsulfinylhexyl isothiocyanate (6-MSITC) found in the rhizome of wasabi has been shown to have anti-inflammatory and antioxidant effects, as well as improve neuroinflammation and memory. Therefore, we...