Preprint now published. See post #6
https://www.medrxiv.org/content/10.1101/2023.12.18.23299958v1
Prevalence of orthostatic intolerance in Long Covid clinic patients – A multicentre observational study
Cassie Lee1(0009-0004-9449-0932) Darren C Greenwood2, Harsha Master3, Kumaran...
Cardiac Origins of the Postural Orthostatic Tachycardia Syndrome
Fu; VanGundy; Galbreath; Shibata; Jain; Hastings; Bhella; Levine
Objectives
The purpose of this study was to test the hypothesis that a small heart coupled with reduced blood volume contributes to the postural orthostatic...
Renin-Aldosterone Paradox and Perturbed Blood Volume Regulation Underlying Postural Tachycardia Syndrome
Satish R. Raj; Italo Biaggioni; Paula C. Yamhure; Bonnie K. Black; Sachin Y. Paranjape; Daniel W. Byrne; David Robertson
Background
Patients with postural tachycardia syndrome (POTS)...
Dysautonomia, but Not Cardiac Dysfunction, Is Common in a Cohort of Individuals with Long COVID
Tabacof, Laura; Wood, Jamie; Breyman, Erica; Tosto-Mancuso, Jenna; Kelly, Amanda; Wilkey, Kaitlyn; Zhang, Chi; Putrino, David; Kontorovich, Amy
Despite the prevalence of dysautonomia in people with...
Full title: Validation of symptom measures in patients under investigation for postural orthostatic tachycardia syndrome (POTS): The Orthostatic Grading Scale (OGS) and the Symptom Screen for Small-fiber Polyneuropathy (SSS)
Highlights
More standardized symptom reporting is needed in Postural...
Autonomic Manifestations of Long-COVID Syndrome
Hira, Rashmin; Karalasingham, Kavithra; Baker, Jacquie R.; Raj, Satish R.
Purpose of Review
Long-COVID is a novel condition emerging from the COVID-19 pandemic. Long-COVID is characterized by symptoms commonly seen in autonomic disorders including...
Influence of end-tidal CO2 on cerebral blood flow during orthostatic stress in controls and adults with myalgic encephalomyelitis/chronic fatigue syndrome
C. (Linda) M. C. van Campen; Peter C. Rowe; Freek W. A. Verheugt; Frans C. Visser
Brain perfusion is sensitive to changes in CO2 levels (CO2...
The Long-COVID autonomic syndrome in hospitalized patients: A one-year prospective cohort study
Stefano Rigo; Franca Barbic; Kareem Khalaf; Andrea Bisoglio; Margherita Pani; Maura Minonzio; Luca Rinaldi; Michele Ciccarelli; Maria Grazia Bordoni; Paolo Verzeletti; Fabio Badilini; Stefanos...
Full title: Semi-supervised exercise training program more effective for individuals with postural orthostatic tachycardia syndrome in randomized controlled trial
Abstract
Purpose
Exercise like any medication requires the correct dose; to be effective the appropriate frequency, duration, and...
Venous insufficiency and acrocyanosis in long COVID: dysautonomia
A 33-year-old man was referred to our specialist clinic with a 6-month history of a rapid purple discolouration of his legs on standing; he reported that his legs would progressively feel heavy, tingly, itchy, and become dusky in...
Ivabradine effects on COVID-19-associated postural orthostatic tachycardia syndrome: a single center prospective study
Background: A wide range of cardiac arrhythmias were reported in the setting of active infection or as a complication of COVID-19. The main pathophysiology can be attributed...
Abstract
Background: Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous condition predominantly affecting autonomic control of the cardiovascular system. Its extensive symptom diversity implies multi-organ involvement that interacts in ways still requiring full exploration...
High incidence of autonomic dysfunction and postural orthostatic tachycardia syndrome in patients with long-COVID: Implications for management and healthcare planning
Marie-Claire Seeley; Celine Gallagher; Eric Ong; Amy Langdon; Jonathan Chieng; Danielle Bailey; Amanda Page; Han S. Lim; Dennis H...
3 Years Into Long COVID: Where Do We Go From Here?
https://www.medscape.com/viewarticle/993827
"... approximately 6% of all US adults are currently experiencing long COVID, with Hispanic/Latinx individuals, transgender individuals, and cis female individuals facing the highest rates."...
Abstract
Background
Many patients with postural orthostatic tachycardia syndrome (POTS) are hypovolemic with plasma volume deficits of 10–30 %. Some also have low levels of aldosterone and diminished aldosterone-renin ratios despite elevations in angiotensin II, pointing to potential adrenal...
Full title: Poor health-related quality of life in postural orthostatic tachycardia syndrome in comparison with a sex- and age-matched normative population
Purpose
The effect of postural orthostatic tachycardia syndrome (POTS) on health-related quality of life (HrQoL) remains poorly studied...
Full title:
Cognitive functioning in postural orthostatic tachycardia syndrome among different body positions: a prospective pilot study (POTSKog study)
Abstract
Purpose
Approximately 96% of patients with postural orthostatic tachycardia syndrome (PoTS) report cognitive complaints. We...
Detecting Orthostatic Intolerance in Long COVID in a Clinic Setting
Isaac, Robert Oliver; Corrado, Joanna; Sivan, Manoj
Introduction:
A likely mechanism of Long COVID (LC) is dysautonomia, manifesting as orthostatic intolerance (OI). In our LC service, all patients underwent a National...
Abstract
50% of POTS patients are hypocapnic during orthostasis related to initial orthostatic hypotension (iOH). We determined whether iOH drives hypocapnia in POTS by low BP or decreased cerebral blood flow velocity (CBFv). We studied 3 groups; healthy volunteers (N=32, 18±3y) were compared...
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