Pathophysiology and Management of Postural Orthostatic Tachycardia Syndrome (POTS): A Literature Review
Mohamad Ghazal, Abdul Rahman Akkawi, Andrew Fancher, Emmanuel Oundo, Hammad Tanzeem, Laiba Sajjad, Alexandros Briasoulis
Abstract
Postural Orthostatic Tachycardia Syndrome (POTS) is a form...
Abstract
Background: Postural Orthostatic Tachycardia Syndrome (POTS) is a syndrome of an exaggerated heart rate (HR) response with standing, disproportionately affecting young women associated with exercise intolerance due to dizziness, palpitations, and/or chest pain.
Research question: How...
Objective: This review aims to identify the exercise rehabilitation approaches used for patients with POTS (Postural Orthostatic Tachycardia Syndrome).
Methods: An electronic literature search was conducted using the PubMed database, covering January 2005 to October 2023. Studies were included...
Karolinska in Sweden is currently running an EECP clinical trial for long covid.
Mekanisk perifer kompression (EECP)-behandling till patienter med postcovid symtom.
https://www.karolinska.se/forskning-och-utbildning/kliniska-provningar/pagaende-kliniska-studier/eecplngtidscovid/
Signicant Microvascular Abnormalities Are Present in Autonomic Dysfunction: Results of a Prospective Study
Sehreen Mumtaz, et. al.
Abstract
Purpose The prevalence and phenotype of capillaroscopic abnormalities in patients with autonomic nervous system dysfunction has not been investigated...
Dietary sodium and health: How much is too much for those with orthostatic disorders?
Stock; Chelimsky; Edwards; Farquhar
High dietary salt (NaCl) increases blood pressure (BP) and can adversely impact multiple target organs including the vasculature, heart, kidneys, brain, autonomic nervous...
Abstract
Background
Compression garments reduce heart rate and symptoms in patients with postural orthostatic tachycardia syndrome in an acute laboratory setting. Patients taking medications controlling heart rate have less benefit from compression than those not on medications. The...
Purpose: The exact etiology of Postural Orthostatic Tachycardia Syndrome (POTS) is still unknown but is likely heterogeneous and multifaceted, involving autoimmune, neuropathic, hypovolemic, and hyperadrenergic pathways. Recently, more research has been devoted to understanding POTS’s underlying...
Peter Novak and David Systrom, etc. Peter Rowe is a reviewer…
one quote from the paper:
Our study provides additional evidence of importance of cerebral blood flow and respiratory system in orthostatic intolerance syndromes without orthostatic hypotension...
Abstract
BACKGROUND:
Postural orthostatic tachycardia syndrome (POTS) is a frequently diagnosed cardiovascular disorder after COVID-19 infection. POTS is characterized by the presence of excessive sinus tachycardia on standing without a fall in blood pressure (BP). We investigated the BP profile...
Pretty interesting opinion piece. Final author listed is Dr. Blair Grubb.
here is an quote from it (my bolding):
In summary, diagnostic criteria for POTS and other common autonomic disorders have been established and are vastly different from the diagnostic criteria of FND (Table 1)...
https://cep.health/clinical-products/fm-mecfs-pots/
Introduction
Fibromyalgia (FM), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), and Postural Orthostatic Tachycardia Syndrome (POTS) are chronic health conditions. Accurate diagnosis and targeted management can improve the...
Editorial in Hypertension by Melanie Dani and Artur Fedorowski
https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.124.23716
Full article is paywalled
Abstract
BACKGROUND:
A subset of patients with postural tachycardia syndrome (POTS) are thought to have a primary hyperadrenergic cause. We assessed clinical biomarkers to identify those that would benefit from sympatholytic therapy.
METHODS:
We measured sympathetic function (supine muscle...
Rachel, the founder of Awareness for POTSies, has developed an online pilot self-advocacy program as a part of her doctoral training at The George Washington University.
It's free to sign up at the moment.
https://www.awarenessforpotsies.org/self-advocacy-program
I'd like to warmly recommend...
Introduction: Postural orthostatic tachycardia syndrome is a debilitating disorder. We compared paediatric patients with this dysautonomia presenting with and without peak upright heart rate > 100 beats per minute.
Materials and methods: Subjects were drawn from the Postural Orthostatic...
Highlights
POTS causes cardiovascular instability and severe symptoms.
Postural hyperventilation is thought to cause POTS, but the mechanisms are unclear.
Reduced stroke volume and brain perfusion drive postural hyperventilation in POTS.
Stroke volume and brain perfusion should be targeted as...
Abstract
Postural orthostatic tachycardia syndrome (POTS) occurs in approximately 30% of people with highly symptomatic post-COVID-19 condition (PCC). It involves several symptoms that limit physical and psychological functions and cause reduced quality of life.
Evidence for different...
Orthostatic Intolerance in Children With Long COVID Utilizing a 10-Minute Passive Standing Test
Amanda K. Morrow; Cindy Villatoro; Christina Kokorelis; Peter C. Rowe; Laura A. Malone
Despite there being a wide variety of symptoms reported in pediatric long COVID, one condition that has become...
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