pace trial

When PACE-Gate Meets Sample Size Nuno Sepúlveda [Conference paper] Abstract PACE-Gate is the name by which the case surrounding the high-profile PACE clinical trial became publicly known. This case ended up in controversy due to a change in the pre-trial primary endpoint and a re-definition...

Hi I’m interested in having a copy of the documents in the subsection “for doctors” and “for patients” in this me-pedia page https://me-pedia.org/wiki/PACE_trial_documents However when I download them I just get a html version of the mepedia front page. Not sure if its because im on my phone...

As noted in some discussions on the forum, many of us feel that a Panorama-style programme on the PACE trial and the wider story of ME/CFS is much warranted and overdue. There are people on Twitter who feel the same. I have decided that it would be good to contact Panorama (and potientially...

Bias, misleading information and lack of respect for alternative views have distorted perceptions of myalgic encephalomyelitis/chronic fatigue syndrome and its treatment Abstract The PACE trial is one of the most recent studies evaluating cognitive behavioural therapy and graded exercise...

"Colin Blakemore (1944–2022) Neuroscientist, science communicator and advocate for openness in research." "In the 2010s, a small, outspoken group of campaigners demanded the retraction of MRC-funded research into chronic fatigue syndrome, also known as myalgic encephalomyelitis, which found...

Posts moved from the NICE guideline thread and the PACE trial thread. New article from Peter White

Tuller D. Once again, the PACE authors respond to concerns with empty answers. Journal of Health Psychology. 2017;22(9):1118-1122. doi:10.1177/1359105317703788 Abstract In their response to Geraghty, the PACE investigators state that they have “repeatedly addressed” the various methodological...

I thought it might be useful for us to get to grips with this issue. The GET defenders have said that NICE chose the trial endpoints it looked at incorrectly. As I understand it, NICE chose the longest followup points where possible, and in the case of PACE, that was 135 weeks. The GET...

(Most links seem to work from the website itself) Includes: Overview News Published Papers Trial Information FAQ Links https://www.qmul.ac.uk/wiph/centres/centre-for-psychiatry-and-mental-health/research/pace-trial/ Link edited 19/11/21 And updated again 17/10/21

How the Lancet lost our trust Stuart Ritchie The Spectator (UK) 26/06/2021 A few of us have tried to get Ritchie interested in the PACE trial, but he has previously refused. But since it now seems to support his argument, he does cautiously mention it...

This post is copied and some posts discussing the article moved from this thread. BMJ feature: Chronic fatigue syndrome and long covid: moving beyond the controversy Long article, which starts with fun stuff like: “I submitted the first positive trial of cognitive behavioural therapy [CBT] as...

https://www.elsevier.com/connect/the-lancet-eic-honored-as-leading-scientific-and-human-rights-voice-at-forefront-of-pandemic cough; PACE trial is still there Dr Horton.

A person has contacted me to see if I could assist in finding the source/complete document of the application to MRC for the PACE trial. First page of the relevant document is in the picture. I can be contacted via DM or tomkindlon{a}hotmail.com

https://www.sciencedirect.com/science/article/pii/S0022399914001883?via%3Dihub (was this data ever released?)

Part of: BJPsych Advances Cochrane Corner and Round the Corner Collection Published online by Cambridge University Press: 11 April 2018 " Editor's summary In a recent Round the Corner, Mitchell commented on a Cochrane Review of exercise therapy for chronic fatigue syndrome (CFS). One of the...

obviously not new. " Summary Background The PACE trial found that, when added to specialist medical care (SMC), cognitive behavioural therapy (CBT), or graded exercise therapy (GET) were superior to adaptive pacing therapy (APT) or SMC alone in improving fatigue and physical functioning in...

Links to posts linking to articles/videos: Jan 2021 article in the Guardian Apr 2021 article in the Guardian Jul 2021 interview video ************************ Not sure if these have been posted in other threads but I think they are significant so I’m posting them in their own thread. For...

Moved from this thread It was suggested yesterday that this Member of the House of Lords local to me is joining Forward ME? She has been asking pertinent questions.... Baroness Scott of Needham Market Liberal Democrat To ask Her Majesty's Government why Chronic Fatigue Syndrome (CFS)...

Hey Someone anonymous from Norway have produced a very thorough two part series on different topics (PACE, Lightning Process etc.) It has english subtitles so everyone can watch

"Treatment harms to patients with ME/CFS" Quote: - Despite evidence of physiological and cellular abnormalities in myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS), the dominant therapeutic approach has been cognitive behaviour therapy (CBT) and graded exercise therapy (GET)...