Deconditioning does not explain orthostatic intolerance in ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome)
Abstract
Background
Orthostatic intolerance (OI) is a frequent finding in individuals with myalgic encephalomyelitis /chronic fatigue syndrome (ME/CFS). Published studies...
Copied post, from NIH: Decoding the Mysteries of Postural Orthostatic Tachycardia Syndrome
From PubMed: Clin Auton Res.
. 2013 Aug;23(4):175-9. doi: 10.1007/s10286-013-0198-6. Epub 2013 May 30.
Low iron storage and mild anemia in postural tachycardia syndrome in adolescents
Imad T Jarjour 1...
Quotes:
As a person living with POTS, Goff wants to see researchers focus more on why POTS happens. “I feel like current treatments aren’t really getting to the root problem, and I also worry about the effects of taking steroids long term,” Goff said. “I’d like to see possibly better treatments...
Abstract
Background
High sodium intake is recommended for the treatment of postural tachycardia syndrome (POTS) to counteract the hypovolemia and elevated plasma norepinephrine that contribute to excessive orthostatic tachycardia, but evidence of its efficacy is not available.
Objectives
This...
https://www.acpjournals.org/do/10.5555/comment1538/full/
Name: Peter C. Rowe
Email: XXXXXXXXXXXXXXXX
Affiliation: Johns Hopkins University
Pubdate: 12 April 2019
Title: Response to Michael Sharpe
Comment: To The Editor:
https://adc.bmj.com/content/105/Suppl_1/A2.2
Tilt positive pots (postural orthostatic tachycardia syndrome): a case series study
FREE
The text with three tables are free at link
Reductions in Cerebral Blood Flow Can Be Provoked by Sitting in Severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
https://www.mdpi.com/2227-9032/8/4/394
Full title: Orthostatic stress testing in myalgic encephalomyelitis/chronic fatigue syndrome patients with or without concomitant fibromyalgia: effects on pressure pain thresholds and temporal summation
Paywall, https://www.clinexprheumatol.org/abstract.asp?a=15665
Unable to access via Sci hub...
Full title: Functional gastrointestinal disorders are increased in joint hypermobility‐related disorders with concomitant postural orthostatic tachycardia syndrome
Open access, https://onlinelibrary.wiley.com/doi/full/10.1111/nmo.13975?af=R
I happened to stumble across this POTS research today:
Splanchnic Venous Compression Enhances the Effects of ß‐Blockade in the Treatment of Postural Tachycardia Syndrome
Emily C. Smith, André Diedrich, Satish R. Raj, Alfredo Gamboa, Cyndya A. Shibao, Bonnie K. Black, Amanda Peltier, Sachin Y...
https://www.mdpi.com/2227-9032/8/2/169
Looks like this study is related to this one discussed here:
https://www.s4me.info/threads/cerebral-blood-flow-is-reduced-in-me-cfs-during-head-up-tilt-testing-even-in-the-absence-of-hypotension-or-tachycardia-van-campen-et-al-2020.13583/
This preprint is under consideration at Journal of Translational Medicine. Preprints are preliminary reports that have not undergone peer review. They should not be considered conclusive, used to inform clinical practice, or referenced by the media as validated information...
https://www.sciencedirect.com/science/article/abs/pii/S0828282X19315508
Edited to add: Full article https://www.onlinecjc.ca/article/S0828-282X(19)31550-8/fulltext
Canadian Journal of Cardiology
Volume 36, Issue 3, March 2020, Pages 357-372
Full title:
Cerebral blood flow is reduced in ME/CFS during head-up tilt testing even in the absence of hypotension or tachycardia: a quantitative, controlled study using Doppler echography
https://www.sciencedirect.com/science/article/pii/S2467981X20300044
Patients were classified as...
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