mitochondria

  1. SNT Gatchaman

    Preprint Frataxin Deficiency Drives Shift from Mitochondrial Metabolism to Glucose Catabolism, Triggering Inflammatory Phenotype in Microglia,2023,Sciarretta+

    Frataxin Deficiency Drives a Shift from Mitochondrial Metabolism to Glucose Catabolism, Triggering an Inflammatory Phenotype in Microglia Francesca Sciarretta; Fabio Zaccaria; Andrea Ninni; Veronica Ceci; Riccardo Turchi; Savina Apolloni; Valerio Chiurchiu; Marta Tiberi; Nadia D'Ambrosi; Silvia...
  2. SNT Gatchaman

    YouTube — The Guy Foundation: Mitochondria and space

    I haven't had the chance to watch this yet, but the speakers are the two senior authors of Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts (2023)
  3. SNT Gatchaman

    Mitochondrial DNA damage triggers spread of Parkinson’s disease-like pathology, 2023, Tresse et al.

    Mitochondrial DNA damage triggers spread of Parkinson’s disease-like pathology Tresse, Emilie; Marturia-Navarro, Joana; Sew, Wei Qi Guinevere; Cisquella-Serra, Marina; Jaberi, Elham; Riera-Ponsati, Lluis; Fauerby, Natasha; Hu, Erling; Kretz, Oliver; Aznar, Susana; Issazadeh-Navikas, Shohreh In...
  4. E

    Mitochondrial proteome research: the road ahead, 2023, Zakery N. Baker, Patrick Forny & David J. Pagliarini

    Mitochondrial proteome research: the road ahead Abstract Mitochondria are multifaceted organelles with key roles in anabolic and catabolic metabolism, bioenergetics, cellular signalling and nutrient sensing, and programmed cell death processes. Their diverse functions are enabled by a...
  5. SNT Gatchaman

    [Preprint] Metabolic and mitochondria alterations induced by SARS-CoV-2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10, 2023, Lopez-Ayllon et al.

    Metabolic and mitochondria alterations induced by SARS-CoV-2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10 Blanca D. Lopez-Ayllon; Silvia Marin; Marcos Farinas Fernandez; Transito Garcia-Garcia; Raul Fernandez-Rodriguez; Ana de Lucas-Rius; Natalia Redondo; Laura Mendoza-Garcia; Carles Foguet...
  6. SNT Gatchaman

    Plasma proteomics show altered inflammatory and mitochondrial proteins in patients with ... post-acute sequelae of SARS-CoV-2, 2023, B. Hanson et al

    Plasma proteomics show altered inflammatory and mitochondrial proteins in patients with neurologic symptoms of post-acute sequelae of SARS-CoV-2 infection Hanson; Visvabharathy; Orban; Jimenez; Batra; Liotta; DeLisle; Klausner; Cohen; Padhye; Tachas; Koralnik Persistent symptoms of COVID-19...
  7. SNT Gatchaman

    Preprint Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response MERSR and its Impact on Proteostasis, 2023, Li et al.

    Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response MERSR and its Impact on Proteostasis Jeson J Li; Nan Xin; Chunxia Yang; Larrisa A Tavizon; Ruth Hong; Travis I Moore; Rebecca G Tharyan; Adam Antebi; Hyun-Eui Kim Maintaining protein homeostasis is essential...
  8. SNT Gatchaman

    Structural and functional impairments of skeletal muscle in patients with [PASC], 2023, Colosio et al.

    Structural and functional impairments of skeletal muscle in patients with post-acute sequelae of SARS-CoV-2 infection Marta Colosio ; Lorenza Brocca ; Marco Gatti ; Marianna Neri ; Emanuela Crea ; Francesca Cadile ; Monica Canepari ; Maria Antonietta Pellegrino ; Biagio Polla ; Simone...
  9. Hutan

    Mitochondria as target to inhibit proliferation and induce apoptosis of cancer cells: the effects of doxycycline and gemcitabine, 2020, Dijk et al

    https://www.nature.com/articles/s41598-020-61381-9#Fig1 Doxycycline has anti-tumour effects in a range of tumour systems. The aims of this study were to define the role mitochondria play in this process and examine the potential of doxycycline in combination with gemcitabine. We studied the...
  10. SNT Gatchaman

    Reduced athletic performance post-COVID-19 is associated with reduced anaerobic threshold, 2023, Barker-Davies et al.

    Reduced athletic performance post-COVID-19 is associated with reduced anaerobic threshold Robert M Barker-Davies; Peter Ladlow; Rebecca Chamley; Edward Nicol; David A Holdsworth Detailed characterisation of cardiopulmonary limitations in patients post-COVID-19 is currently limited, particularly...
  11. SNT Gatchaman

    Role of miR-2392 in driving SARS-CoV-2 infection, 2021, McDonald et al.

    Role of miR-2392 in driving SARS-CoV-2 infection J. Tyson McDonald; Francisco J. Enguita; Deanne Taylor; Robert J. Griffin; Waldemar Priebe; Mark R. Emmett; Mohammad M. Sajadi; Anthony D. Harris; Jean Clement; Joseph M. Dybas; Nukhet Aykin-Burns; Joseph W. Guarnieri; Larry N. Singh; Peter...
  12. SNT Gatchaman

    Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts, 2023, Guarnieri et al.

    Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts Joseph W. Guarnieri; Joseph M. Dybas; Hossein Fazelinia; Man S. Kim; Justin Frere; Yuanchao Zhang; Yentli Soto Albrecht; Deborah G. Murdock; Alessia Angelin; Larry N. Singh; Scott L. Weiss; Sonja M...
  13. SNT Gatchaman

    A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy, 2023, Southwell et al.

    A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy Nneka Southwell; Guido Primiano; Viraj Nadkarni; Nabeel Attarwala; Emelie Beattie; Dawson Miller; Sumaitaah Alam; Irene Liparulo; Yevgeniya I Shurubor; Maria Lucia Valentino; Valerio Carelli; Serenella...
  14. SNT Gatchaman

    Mitochondria and oxygen homeostasis, 2022, Mori, Hwang et al.

    Mitochondria and oxygen homeostasis Mateus P. Mori; Rozhin Penjweini; Jay R. Knutson; Ping-yuan Wang; Paul M. Hwang Molecular oxygen possesses a dual nature due to its highly reactive free radical property: it is capable of oxidizing metabolic substrates to generate cellular energy, but can...
  15. SNT Gatchaman

    Exercise and vascular function in sedentary lifestyles in humans, 2023, Fasipe et al.

    Exercise and vascular function in sedentary lifestyles in humans Fasipe, Babatunde; Li, Shunchang; Laher, Ismail People with sedentary lifestyles engage in minimal or no physical activity. A sedentary lifestyle promotes dysregulation of cellular redox balance, diminishes mitochondrial function...
  16. rvallee

    Mitochondrial impairment but not peripheral inflammation predicts greater Gulf War illness severity, 2023, Patel et al

    Mitochondrial impairment but not peripheral inflammation predicts greater Gulf War illness severity https://www.nature.com/articles/s41598-023-35896-w Published: 12 July 2023 Gulf War illness (GWI) is an important exemplar of environmentally-triggered chronic multisymptom illness, and a...
  17. Mij

    Environmental and behavioral regulation of HIF-mitochondria crosstalk, 2023, Johannes Burtscher et al

    Highlights Hypoxia inducible factors – mitochondria crosstalk underlies adaptations to hypoxia. Controlled induction of hypoxia responses yields potent health benefits. Environmental and behavioral conditions modulate adaptations to hypoxia. Understanding the determinants of adaptation...
  18. SNT Gatchaman

    Preprint Matrix stiffening promotes perinuclear clustering of mitochondria, 2023, Daga et al.

    Matrix stiffening promotes perinuclear clustering of mitochondria Piyush Daga; Basil Thurakkal; Simran Rawal; Tamal Das Mechanical cues from the tissue microenvironment, such as the stiffness of the extracellular matrix, modulate cellular forms and functions. As numerous studies have shown...
  19. SNT Gatchaman

    Preprint Mitochondria- and ER-associated actin are required for mitochondrial fusion, 2023, Gatti et al.

    Mitochondria- and ER-associated actin are required for mitochondrial fusion Priya Gatti; Cara R Schiavon; Uri Manor; Marc Germain Mitochondria play a crucial role in the regulation of cellular metabolism and signalling. Mitochondrial activity is modulated by the processes of mitochondrial...
  20. SNT Gatchaman

    Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact, 2020, Silveira et al.

    Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact Willian A. da Silveira; Hossein Fazelinia; Sara Brin Rosenthal; Evagelia C. Laiakis; Man S. Kim; Cem Meydan; Yared Kidane; Komal S. Rathi; Scott M. Smith; Benjamin Stear; Yue Ying...
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