mitochondria

  1. Dolphin

    Mitochondrial function in patients affected with fibromyalgia syndrome is impaired and correlates with disease severity, 2024, Macchi

    https://www.researchsquare.com/article/rs-4654793/v1 Mitochondrial function in patients affected with fibromyalgia syndrome is impaired and correlates with disease severity Chiara Macchi1 Andrea Giachi1 Isabella Fichtner1 Silvia Pedretti1 Piercarlo Sarzi Puttini2 Nico Mitro1 Alberto...
  2. R

    "CFS" and fibro "after" sarcoidosis

    Numerous people are being diagnosed as having CFS and fibro after apparent remission of sarcoidosis. Numerous questions arise 1) What does the diagnoser know about CFS or fibro? 2) What does the diagnoser know about work on post sarcoid fatigue vs sarcoid e.g. persistent shift to TH1 in post...
  3. Andy

    Dengue virus non-structural protein 3 inhibits mitochondrial respiration by impairing complex I function 2024 Sousa et al

    ABSTRACT Dengue virus (DENV) infection is known to affect host cell metabolism, but the molecular players involved are still poorly known. Using a proteomics approach, we identified six DENV proteins associated with mitochondria isolated from infected hepatocytes, and most of the peptides...
  4. Andy

    Mitochondrial structural alterations in fibromyalgia: a pilot electron microscopy study 2024 Israel et al

    Abstract OBJECTIVES: The pathogenesis of fibromyalgia (FM), characterised by chronic widespread pain and fatigue, remains notoriously elusive, hampering attempts to develop disease modifying treatments. Mitochondria are the headquarters of cellular energy metabolism, and their malfunction has...
  5. forestglip

    BBC: How Long Concussion could offer new insights into Long Covid

    Link to article By David Cox
  6. SNT Gatchaman

    Preprint Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST, 2024, Sprenger et al.

    Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST Hans-Georg Sprenger; Melanie J. Mittenbühler; Yizhi Sun; Jonathan G. Van Vranken; Sebastian Schindler; Abhilash Jayaraj; Sumeet A. Khetarpal; Ariana Vargas-Castillo; Anna M. Puszynska; Jessica...
  7. SNT Gatchaman

    Preprint miR-29a-3p, a new myokine orchestrating resistance exercise via coordinated metabolic responses, 2024, Pinto-Hernandez et al.

    miR-29a-3p, a new myokine orchestrating resistance exercise via coordinated metabolic responses Paola Pinto-Hernandez; Manuel Fernandez-Sanjurjo; Daan Paget; Xurde M Caravia; David Roiz-Valle; Juan Castilla-Silgado; Sergio Diez-Robles; Almudena Coto-Vilcapoma; Pau Gama; Pablo M Garcia-Roves...
  8. Dolphin

    Mitochondrial DNA Missense Mutations ... Identified in a Caucasian Female with (ME/CFS) Triggered by the [EBV],2024,Tang-Siegel

    https://www.hindawi.com/journals/crig/2024/6475425/ Full title: Mitochondrial DNA Missense Mutations ChrMT: 8981A > G and ChrMT: 6268C > T Identified in a Caucasian Female with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Triggered by the Epstein–Barr Virus Abstract Myalgic...
  9. SNT Gatchaman

    Preprint Oxidative Stress is a shared characteristic of ME/CFS and Long COVID, 2024, Shankar, Bonilla, Davis et al.

    Oxidative Stress is a shared characteristic of ME/CFS and Long COVID Vishnu Shankar; Julie Wilhelmy; Basil Michael; Layla Cervantes; Vamsee Mallajosyula; Ronald Davis; Michael Snyder; Shady Younis; William H Robinson; Sadasivan Shankar; Paul Mischel; Hector Bonilla; Mark Davis More than 65...
  10. SNT Gatchaman

    Preprint Subcellular imaging of lipids and sugars using genetically encoded proximity sensors, 2024, Moore et al.

    Subcellular imaging of lipids and sugars using genetically encoded proximity sensors William M. Moore; Roberto J. Brea; Caroline Knittel; Ellen Wrightsman; Brandon Hui; Jinchao Loui; Christelle F. Ancajas; Michael D. Best; Neal K. Devaraj; Itay Budin Live cell imaging of lipids and other...
  11. SNT Gatchaman

    Review Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches, 2024, Molnar et al.

    Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches Molnar, Tihamer; Lehoczki, Andrea; Fekete, Monika; Varnai, Reka; Zavori, Laszlo; Erdo-Bonyar, Szabina; Simon, Diana; Berki, Tímea; Csecsei, Peter; Ezer, Erzsebet The COVID-19 pandemic, caused...
  12. Andy

    Preprint The Energetic Stress Marker GDF15 is Induced by Acute Psychosocial Stress, 2024, Huang et al

    Preprint Psychobiological regulation of plasma and saliva GDF15 dynamics in health and mitochondrial diseases Abstract GDF15 (growth differentiation factor 15) is a marker of cellular energetic stress linked to physical-mental illness, aging, and mortality. However, questions remain about its...
  13. SNT Gatchaman

    Transcription Profile Analysis of Vastus Lateralis Muscle from Patients with Chronic Fatigue Syndrome, 2009, Pietrangelo et al.

    Transcription Profile Analysis of Vastus Lateralis Muscle from Patients with Chronic Fatigue Syndrome T. Pietrangelo; R. Mancinelli; L. Toniolo; G. Montanari; J. Vecchiet; G. Fanò; S. Fulle Chronic fatigue syndrome (CFS) is a disabling condition characterized by unexplained chronic fatigue that...
  14. SNT Gatchaman

    Review SARS-CoV-2 Mitochondrial Metabolic and Epigenomic Reprogramming in COVID-19, 2024, Guarnieri et al.

    SARS-CoV-2 Mitochondrial Metabolic and Epigenomic Reprogramming in COVID-19 Guarnieri; Haltom; Albrecht; Lie; Olali; Widjaja; Ranshing; Angelin; Murdock; Wallace To determine the effects of SARS-CoV-2 infection on cellular metabolism, we conducted an exhaustive survey of the cellular metabolic...
  15. SNT Gatchaman

    Review Mitochondrial quality control pathways sense mitochondrial protein import, 2023, Laurie P. Lee-Glover and Timothy E. Shutt

    Mitochondrial quality control pathways sense mitochondrial protein import Laurie P. Lee-Glover; Timothy E. Shutt Mitochondrial quality control (MQC) mechanisms are required to maintain a functional proteome, which enables mitochondria to perform a myriad of important cellular functions from...
  16. Andy

    Mitochondrial complex I activity in microglia sustains neuroinflammation 2024 Peruzzotti-Jametti et al

    Abstract Sustained smouldering, or low-grade activation, of myeloid cells is a common hallmark of several chronic neurological diseases, including multiple sclerosis1. Distinct metabolic and mitochondrial features guide the activation and the diverse functional states of myeloid cells2...
  17. Andy

    Comparison of the muscle oxygenation during submaximal and maximal exercise tests in patients post-[COVID-19]... 2024 Başak Kavalcı Kol et al

    Full title: Comparison of the muscle oxygenation during submaximal and maximal exercise tests in patients post-coronavirus disease 2019 syndrome with pulmonary involvement ABSTRACT Introduction Pulmonary involvement is prevalent in patients with coronavirus disease 2019 (COVID-19). Arterial...
  18. Dolphin

    Trial Report Heat treatment in health and disease: How water-filtered infrared-A (wIRA irradiation affects key cellular mechanisms in ME/CFS, 2024, Hochecker

    https://www.sciencedirect.com/science/article/abs/pii/S0306456524000317 Journal of Thermal Biology Available online 21 February 2024, 103813 In Press, Journal Pre-proof Heat treatment in health and disease: How water-filtered infrared-A (wIRA irradiation affects key cellular mechanisms in...
  19. Mij

    Mitochondrial DNA replication stress triggers a pro-inflammatory endosomal pathway of nucleoid disposal, 2024, Laura E. Newman et al

    Abstract Mitochondrial DNA (mtDNA) encodes essential subunits of the oxidative phosphorylation system, but is also a major damage-associated molecular pattern (DAMP) that engages innate immune sensors when released into the cytoplasm, outside of cells or into circulation. As a DAMP, mtDNA not...
  20. Haveyoutriedyoga

    Glutamate, similarities with underlying mechanisms? ME, PLMD/RLS

    Polysomnography has shown that I have Periodic Limb Movement Disorder (PLMD). I also tick all boxes for RLS (and never been diagnosed with fibromyalgia). I can't describe how happy I was to see, written in black and white, numerically quantified, accompanied by "obviously [patient] has PLMD that...
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