long covid

Immunometabolic rewiring in long COVID patients with chronic headache Suan-Sin Foo, Weiqiang Chen, Kyle L Jung, Tamiris Azamor, Un Yung Choi, Pengfei Zhang, Suzy AA Comhair, Serpil C Erzurum, Lara Jehi, Jae U Jung Almost 20% of patients with COVID-19 experience long-term effects, known as...

Innate immune cell activation causes lung fibrosis in a humanized model of long COVID Lu Cui, Zhuoqing Fang, Cristabelle Madona De Souza, Tristan Lerbs, Yuan Guan, Irene Li, Vivek Charu, Shih-Yu Chen, Irving Weissman, Gerlinde Wernig COVID-19 remains a global pandemic of an unprecedented...

New academic book edited by Leonard Jason & Charles Lapp, "Understanding the Behavioral & Medical Impact of #LongCOVID: An Empirical Guide to Assessment & Treatment of Post-Acute Sequelae of SARS CoV-2 Infection"...

Full title: Multimodal MRI of myalgic encephalomyelitis/chronic fatigue syndrome: A cross-sectional neuroimaging study toward its neuropathophysiology and diagnosis Introduction: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), is a debilitating illness affecting up to 24 million...

A patient who recovered from post-COVID myalgic encephalomyelitis/chronic fatigue syndrome: a case report. Oka T Background: Some patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) complain of persistent fatigue, dyspnea, pain, and cognitive dysfunction...

Neurocognitive and psychiatric symptoms following infection with COVID-19: Evidence from laboratory and population studies Hall PA, Ayaz H, Meng G, Hudson A, Sakib MN, Quah ACK, Agar TK, Lee JA, Boudreau C, Fong GT Objective: The objective of the current investigation was to examine...

Structural brain changes in patients with post-COVID fatigue: a prospective observational study Josephine Heine, Katia Schwichtenberg, Tim J. Hartung, Sophia Rekers, Claudia Chien, Fabian Boesl, Rebekka Rust, Christian Hohenfeld, Julia Bungenberg, Ana S. Costa, Carmen Scheibenbogen, Judith...

Abstract Long-COVID syndrome is associated with high healthcare costs, but its pathophysiology is not yet fully understood. Inflammation, renal impairment or disturbance of the NO system emerge as potential pathogenetic factors. We aimed to investigate the relationship between symptoms of...

Background and purpose: The coronavirus disease 2019 (COVID-19) has been associated with olfactory dysfunction. The persistent symptoms of anosmia or hyposmia were associated in previous studies with the development of memory impairment and mood disturbances. We aimed to investigate the...

Background: The long-term sequelae after COVID-19 constitute a challenge to public health and increased knowledge is needed. We investigated the prevalence of self-reported persistent symptoms and reduced health-related quality of life (HRQoL) in relation to functional exercise capacity, 6...

I'm looking for the early discussion on the S4ME forum but also elsewhere in the ME/CFS patient community of the idea that the corona-pandemic might lead to an increase in ME/CFS incidence. I found this thread which started discussing this at the end of February 2020 but I suspect there will be...

Summary Background Few studies have reported the long-term health effects of COVID-19. The regional population-based Linköping COVID-19 study (LinCoS) included all patients hospitalised due to COVID-19 during the first pandemic wave. Four months post-discharge, over 40% (185/433) experienced...

Free fulltext: https://www.mdpi.com/1660-4601/20/4/3477 Non-Pharmacological Therapies for Post-Viral Syndromes, Including Long COVID: A Systematic Review by by Joht Singh Chandan 1,*,Kirsty R. Brown 1,2,Nikita Simms-Williams 1,Nasir Z. Bashir 3,Jenny Camaradou 4,Dominic Heining 5,Grace M...

The announcement of this study caused a firestorm on Twitter and continues to do so: With the exception of a "clever" acronym, nothing adds more to the credibility of a clinical trial than announcing "promising results" before it has even finished: Amid all the self-serving puffery and...

Authors: Fabricia L. Fontes-Dantas et al Highlights Spike protein infusion into mouse brain induces late cognitive dysfunction Spike protein induces late hippocampal microgliosis and synapse loss Blockage of TLR4 renders mice resistant to Spike-induced cognitive dysfunction TLR4-2604G>A GG...

Toward a Common Research Agenda in Infection-Associated Chronic Illnesses: A Workshop to Examine Common, Overlapping Clinical and Biological Factors The National Academies of Sciences, Engineering, and Medicine The two-day event will be held June 29 and 30 in Washington DC. You can also attend...

Introduction: In children, the manifestations of coronavirus disease 2019 (COVID-19) in the acute phase are considered mild compared with those in adults; however, some children experience a severe disease that requires hospitalization. This study was designed to present the operation and...

Now published - see post Preprint Post-COVID syndrome is associated with capillary alterations, macrophage infiltration and distinct transcriptomic signatures in skeletal muscles Tom Aschman, Emanuel Wyler, Oliver Baum, Andreas Hentschel, Franziska Legler, Corinna Preusse, Lil Meyer-Arndt...