Introduction: Many people with long COVID symptoms suffer from debilitating neurologic post-acute sequelae of SARS-CoV-2 infection (Neuro-PASC). Although symptoms of Neuro-PASC are widely documented, it is still unclear whether PASC symptoms impact virus-specific immune responses. Therefore, we...
Detecting Orthostatic Intolerance in Long COVID in a Clinic Setting
Isaac, Robert Oliver; Corrado, Joanna; Sivan, Manoj
Introduction:
A likely mechanism of Long COVID (LC) is dysautonomia, manifesting as orthostatic intolerance (OI). In our LC service, all patients underwent a National...
Abstract
Rheumatology, such as other subspecialties, has both a unique perspective to offer as well as an evolving role to play in the global COVID-19 pandemic. Our field has already contributed meaningfully to the development and repurposing of many of the immune-based therapeutics which are...
Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection
IMPORTANCE
SARS-CoV-2 infection is associated with persistent, relapsing, or new symptoms or other health effects occurring after acute infection, termed postacute sequelae of SARS-CoV-2 infection (PASC), also known as...
Post-COVID Patients With New-Onset Chronic Pain 2 Years After Infection: Cross-Sectional Study
Andrés Calvache-Mateo; Alba Navas-Otero; Alejandro Heredia-Ciuró; Javier Matín-Núñez; Irene Torres-Sánchez; Laura López-López; Marie Carmen Valenza
Background:
Although pain is common in...
New-onset, self-reported long COVID after coronavirus (COVID-19) reinfection in the UK
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Main points
4.0% of adults (aged 16 years and over) and 1.0% of children and young people (aged 2 to 15 years) reported having long COVID 12 to 20 weeks after a first coronavirus...
ELUCIDate long-term consequences of Childhood Infections using administrative and research Data
https://elucidatestudy.blogs.bristol.ac.uk/about-us/
https://elucidatestudy.blogs.bristol.ac.uk/
Abstract
To describe the prevalence of long COVID in children infected for the first time (n=332) or reinfected (n=243) with Omicron variant SARS-CoV-2, compared with test-negative children (n=311). 12-16% infected with Omicron met the research definition of long COVID at 3 and 6 months after...
Abstract:
Post-COVID-19 syndrome is an ongoing challenge for healthcare systems as well as for society. The clinical picture of post-COVID-19 syndrome is heterogeneous, including fatigue, sleep disturbances, pain, hair loss, and gastrointestinal symptoms such as chronic diarrhea. Neurological...
Systematic review of the prevalence of Long Covid
Woodrow, Mirembe; Carey, Charles; Ziauddeen, Nida; Thomas, Rebecca; Akrami, Athena; Lutje, Vittoria; Greenwood, Darren C; Alwan, Nisreen A
Background:
Long Covid occurs in those infected with SARSCoV2 whose symptoms persist or develop beyond the...
eBioMedicine
Part of THE LANCET Discovery Science
Post COVID-19 condition after delta infection and omicron reinfection in children and adolescents
Summary
Background
The burden of COVID-19 in children and adolescents has increased during the delta and omicron waves, necessitating studies of...
Abstract
Background: One of the major challenges currently faced by global health systems is the prolonged COVID-19 syndrome (also known as long COVID) which has emerged as a consequence of the SARS-CoV-2 epidemic. The World Health Organization (WHO) recognized long COVID as a distinct clinical...
Neurology, Neuroimmunology & Neuroinflammation
Deep Phenotyping of Neurologic Postacute Sequelae of SARS-CoV-2 Infection
Abstract
Background and Objectives SARS-CoV-2 infection has been associated with a syndrome of long-term neurologic sequelae that is poorly characterized. We aimed to...
Aims and Objectives
In this study, we aimed to characterize the impact of long COVID on quality of life and approaches to symptom management among Black American adults.
Background
As a novel condition, qualitative evidence concerning long COVID symptoms and their impact on quality of life can...
Viral persistence, reactivation, and mechanisms of long COVID
Benjamin Chen; Boris Julg; Sindhu Mohandas; Steven B Bradfute; RECOVER Mechanistic Pathways Task Force; Zaki A Sherif; Christian R Gomez; Thomas J Connors; Timothy J Henrich; W Brian Reeves; K Coombs; C Kim; Pras Jagannathan...
Abstract
Introduction
At the pandemic's beginning, significant concern has risen about the prevalence of myocardial involvement after SARS-CoV-2 infection. We assessed the cardiovascular burden of SARS-CoV-2 in a large cohort of athletes and identified factors that might affect the disease...
Full title:
Clinical improvement of Long-COVID is associated with reduction in autoantibodies, lipids, and inflammation following therapeutic apheresis
Abstract
In the aftermath of the COVID-19 pandemic, we are witnessing an unprecedented wave of post-infectious complications. Most...
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