fibrinogen

Neurovascular injury with complement activation and inflammation in COVID-19 Myoung-Hwa Lee, Daniel P. Perl, Joseph Steiner, Nicholas Pasternack, Wenxue Li, Dragan Maric, Farinaz Safavi, Iren Horkayne-Szakaly, Robert Jones, Michelle N. Stram, Joel T. Moncur, Marco Hefti, Rebecca D. Folkerth...

Amyloidogenesis of SARS-CoV-2 Spike Protein Sofie Nyström, Per Hammarström Abstract SARS-CoV-2 infection is associated with a surprising number of morbidities. Uncanny similarities with amyloid-disease associated blood coagulation and fibrinolytic disturbances together with neurologic and...

SARS-CoV-2 spike protein induces abnormal inflammatory blood clots neutralized by fibrin immunotherapy (Non peer-reviewed) Jae Kyu Ryu, Elif G Sozmen, Karuna Dixit, Mauricio Montano, Yusuke Matsui, Yixin Liu, Ekram Helmy, Thomas J Deerinck, Zhaoqi Yan, Renaud Schuck, Rosa Meza Acevedo, Collin M...

A macrophage attack culminating in microthromboses characterizes COVID 19 pneumonia Brian S Bull, Karen L Hay Introduction: A neutrophilic infiltrate characterizes bacterial pneumonia. Macrophage infiltration is similarly characteristic of the viral pneumonia caused by SARS-CoV-2. These...

Poorly controlled type 2 diabetes is accompanied by significant morphological and ultrastructural changes in both erythrocytes and in thrombin-generated fibrin: implications for diagnostics Etheresia Pretorius, Janette Bester, Natasha Vermeulen, Sajee Alummoottil, Prashilla Soma, Antoinette V...

Fibrinogen Glycation and Presence of Glucose Impair Fibrin Polymerization—An In Vitro Study of Isolated Fibrinogen and Plasma from Patients with Diabetes Mellitus Boguslawa Luzak, Magdalena Boncler, Marcin Kosmalski, Ewelina Mnich, Lidia Stanczyk, Tomasz Przygodzki and Cezary Watala Abstract...

Glucose Concentration Affects Fibrin Clot Structure and Morphology as Evidenced by Fluorescence Imaging and Molecular Simulations Jacob E. Hood, Sumith Yesudasan and Rodney D. Averett Abstract Although in vivo studies have been conducted in the past to determine hyperglycemic effects and...

Proteins behaving badly. Substoichiometric molecular control and amplification of the initiation and nature of amyloid fibril formation: lessons from and for blood clotting Douglas Kell and Etheresia Pretorius Abstract The chief and largely terminal element of normal blood clotting is...

SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19 Lize M. Grobbelaar, Chantelle Venter, Mare Vlok, Malebogo Ngoepe, Gert Jacobus Laubscher, Petrus Johannes Lourens, Janami Steenkamp, Douglas B. Kell and Etheresia...

Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation Martin J. Page, Greig J. A. thomson, J. Massimo Nunes, Anna-Mart Engelbrecht, Theo A Nell, Willem J. S. de Villiers, Maria C. de Beer, Lize Engelbrecht, Douglas B. Kell, Etheresia Pretorius Abstract Complex associations...

Chronic fatigue syndrome and/or fibromyalgia as a variation of antiphospholipid antibody syndrome: an explanatory model and approach to laboratory diagnosis Abstract Chronic Fatigue and/or Fibromyalgia have long been diseases without definition. An explanatory model of coagulation...

https://medicalxpress.com/news/2021-05-potential-causality-blood-clot-factors.html

" Inflammatory micro clots in blood of individuals suffering from Long COVID Date: October 4, 2021 Source: Stellenbosch University Summary: Researchers have found an overload of various inflammatory molecules, 'trapped' inside insoluble microscopic blood clots (micro clots), in the blood of...

A comprehensive clinical and laboratory evaluation of 224 patients with persistent symptoms attributed to presumed tick-bite exposure Abstract Background: Persistent symptoms attributed to presumed tick-bite exposure constitute an unresolved medical controversy. We evaluated whether Swedish...