ebv

Latent virus reactivation in astronauts on the international space station Mehta, Satish K.; Laudenslager, Mark L.; Stowe, Raymond P.; Crucian, Brian E.; Feiveson, Alan H.; Sams, Clarence F.; Pierson, Duane L. Reactivation of latent herpes viruses was measured in 23 astronauts (18 male and 5...

https://www.gavi.org/vaccineswork/what-happens-when-you-dont-recover-epstein-barr-virus The author says she had ME/CFS after EBV. (About the author: Priya Joi is a British-Indian science writer based in Barcelona. She was previously a staff writer and editor at the World Health Organization...

A protein from Epstein–Barr virus called EBNA1 has been shown to bind to and break human chromosome 11, producing instability in the genome that might cause a predisposition to cancer. Paywalled. https://www.nature.com/articles/d41586-023-00936-y

EBV dUTPase: A Novel Modulator of Inflammation and the Tumor Microenvironment in EBV-Associated Malignancies Williams, Marshall V.; Mena-Palomo, Irene; Cox, Brandon; Ariza, Maria Eugenia There is increasing evidence that put into question the classical dogma that the Epstein–Barr virus (EBV)...

A promiscuous inflammasome sparks replication of a common tumor virus Eric M. Burton, Raphaela Goldbach-Mansky, Sumita Bhaduri-McIntosh Viruses activate inflammasomes but then subvert resulting inflammatory responses to avoid elimination. We asked whether viruses could instead use such...

Citation : Zhong, L., Krummenacher, C., Zhang, W. et al. Urgency and necessity of Epstein-Barr virus prophylactic vaccines. npj Vaccines 7, 159 (2022). https://doi.org/10.1038/s41541-022-00587-6 Open Access Link : https://www.nature.com/articles/s41541-022-00587-6 I've added paragraphs to...

Abstract Epstein-Barr virus (EBV) persists in human B-cells by maintaining its chromatinized episomes within the nucleus. We have previously shown that cellular factor Poly [ADP-ribose] polymerase 1 (PARP1) binds the EBV genome, stabilizes CTCF binding at specific loci, and that PARP1 enzymatic...

Abstract Beyond their pulmonary disease, many COVID-19 patients experience a complex constellation of characteristics, including hyperinflammatory responses, autoimmune disorders, and coagulopathies. However, the pathogenesis of these aspects of COVID-19 is obscure. More than 90% of people are...

Highlights • Adolescents with CFS report cognitive difficulties. • Adolescents with CFS report more cognitive difficulties than those with CF. • There were no impairments in objective measures of cognitive function. Abstract Objective Cognitive difficulties are among the most disruptive and...

Saliva antibody-fingerprint of reactivated latent viruses after mild/asymptomatic COVID-19 is unique in patients with myalgic-encephalomyelitis/chronic fatigue syndrome Eirini Apostolou, Muhammad Rizwan, Petros Moustardas, Per Sjögren, Bo Christer Bertilson, Björn Bragée, Olli Polo and Anders...

A 63-year-old woman presented with dyspepsia and gastric pain without B symptoms. She had been treated with methotrexate for 8 years for psoriatic arthritis. Endoscopy showed multiple gastric ulcers. Histological examination revealed submucosal infiltration by small- to medium-size lymphoid...

Abstract SARS-CoV-2 infection can result in the development of a constellation of persistent sequelae following acute disease called post-acute sequelae of COVID-19 (PASC) or Long COVID. Individuals diagnosed with Long COVID frequently report unremitting fatigue, post-exertional malaise, and a...

https://www.nature.com/articles/s41579-022-00770-5 Epstein–Barr virus (EBV) is a ubiquitous human lymphotropic herpesvirus with a well-established causal role in several cancers. Recent studies have provided compelling epidemiological and mechanistic evidence for a causal role of EBV in...

I would like to share with you my latest review article. The Epstein-Barr virus (EBV) has long been known to be behind the development of autoimmune diseases, cancer and is even suspected to be behind the development of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Long COVID. But it is...

Abstract Infections by the Epstein-Barr virus (EBV) are often at the disease onset of patients suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). However, serological analyses of these infections remain inconclusive when comparing patients with healthy controls (HCs)...

Full title: EBV/HHV-6A dUTPases contribute to Myalgic Encephalomyelitis/Chronic-Fatigue-Syndrome pathophysiology by enhancing TFH cell differentiation and extrafollicular activities Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a chronic, debilitating multisystem illness of...

Revisiting IgG antibody reactivity to Epstein-Barr virus in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and its potential application to disease diagnosis Abstract: Infections by the Epstein-Barr virus (EBV) are often at the disease onset of patients suffering from Myalgic...

https://www.theatlantic.com/science/archive/2022/03/epstein-barr-virus-mono-cancer-research/623881/ (Could be paywalled, it worked for me) Over the years, more hints of EBV’s unusual abilities started appearing. The virus or the antibodies to it seemed to be disproportionately found in people...

Highlights Longitudinal multiomics associate PASC with autoantibodies, viremia and comorbidities Reactivation of latent viruses during initial infection may contribute to PASC Subclinical autoantibodies negatively correlate with anti-SARS-CoV-2 antibodies Gastrointestinal PASC uniquely present...

Main paper Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system of unknown etiology. We tested the hypothesis that MS is caused by Epstein-Barr virus (EBV) in a cohort comprising more than 10 million young adults on active duty in the US...