ebv

I wasn't sure what prefix to use given that the paper has been accepted in Cell but not published. I read about it in a paywalled news article as the abstract was presented at the ECTRIMS 2023. Ineffective Immune Control of Epstein-Barr Virus-Induced Autoreactive Responses is an Important Cause...

Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID? Abstract Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID (LC) are characterized by similar immunological alterations, persistence of chronic viral infection...

Lymph node targeted multi-epitope subunit vaccine promotes effective immunity to EBV in HLA-expressing mice Dasari, Vijayendra; McNeil, Lisa K.; Beckett, Kirrilee; Solomon, Matthew; Ambalathingal, George; Thuy, T. Le; Panikkar, Archana; Smith, Caitlyn; Steinbuck, Martin P.; Jakubowski, Aniela...

Preprint. Now published see post #6 Abstract Background: Infectious mononucleosis, caused by the Epstein-Barr Virus (EBV-IM), has been linked to the development of myalgic encephalomyelitis/chronic fatigue-syndrome (ME/CFS) in children, adolescents, and young adults. Our study presents the...

Are the integrin binding motifs within SARS CoV-2 spike protein and MHC class II alleles playing the key role in COVID-19? Gerencer, Marijan; McGuffin, Liam J. The previous studies on the RGD motif (aa403-405) within the SARS CoV-2 spike (S) protein receptor binding domain (RBD) suggest that...

Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus Mickaël Bouvet; Stefanie Voigt; Takanobu Tagawa; Manuel Albanese; Yen-Fu Adam Chen; Yan Chen; Devin N. Fachko; Dagmar Pich; Christine Göbel; Rebecca L. Skalsky; Wolfgang...

Association Between Time Spent Outdoors and Risk of Multiple Sclerosis Prince Sebastian; Nicolas Cherbuin; Lisa F. Barcellos; Shelly Roalstad; Charles Casper; Janace Hart; Gregory S. Aaen; Lauren Krupp; Leslie Benson; Mark Gorman; Meghan Candee; Tanuja Chitnis; Manu Goyal; Benjamin Greenberg...

Abstract Myalgic Encephalomyelitis/ Chronic Fatigue syndrome (ME/CFS) is a complex, debilitating, long-term illness without a diagnostic biomarker. ME/CFS patients share overlapping symptoms with long COVID patients, an observation which has strengthened the infectious origin hypothesis of...

Highlights COVID-19 patients have increased incidence of Epstein-Barr Virus reactivation. Detection of EBV DNA is greater among COVID-19 positive patients (27.1% vs 12.5%). No statistical difference in CRP levels of COVID-19 positive vs. negative patients. No statistical difference in...

Cardiovascular involvement is an uncommon but severe complication of Epstein–Barr virus (EBV) infection caused by direct damage and immune injury. Recently, it has drawn increasing attention due to its dismal prognosis. It can manifest in various ways, including coronary artery dilation (CAD)...

Latent virus reactivation in astronauts on the international space station Mehta, Satish K.; Laudenslager, Mark L.; Stowe, Raymond P.; Crucian, Brian E.; Feiveson, Alan H.; Sams, Clarence F.; Pierson, Duane L. Reactivation of latent herpes viruses was measured in 23 astronauts (18 male and 5...

https://www.gavi.org/vaccineswork/what-happens-when-you-dont-recover-epstein-barr-virus The author says she had ME/CFS after EBV. (About the author: Priya Joi is a British-Indian science writer based in Barcelona. She was previously a staff writer and editor at the World Health Organization...

A protein from Epstein–Barr virus called EBNA1 has been shown to bind to and break human chromosome 11, producing instability in the genome that might cause a predisposition to cancer. Paywalled. https://www.nature.com/articles/d41586-023-00936-y

EBV dUTPase: A Novel Modulator of Inflammation and the Tumor Microenvironment in EBV-Associated Malignancies Williams, Marshall V.; Mena-Palomo, Irene; Cox, Brandon; Ariza, Maria Eugenia There is increasing evidence that put into question the classical dogma that the Epstein–Barr virus (EBV)...

A promiscuous inflammasome sparks replication of a common tumor virus Eric M. Burton, Raphaela Goldbach-Mansky, Sumita Bhaduri-McIntosh Viruses activate inflammasomes but then subvert resulting inflammatory responses to avoid elimination. We asked whether viruses could instead use such...

Citation : Zhong, L., Krummenacher, C., Zhang, W. et al. Urgency and necessity of Epstein-Barr virus prophylactic vaccines. npj Vaccines 7, 159 (2022). https://doi.org/10.1038/s41541-022-00587-6 Open Access Link : https://www.nature.com/articles/s41541-022-00587-6 I've added paragraphs to...

Abstract Epstein-Barr virus (EBV) persists in human B-cells by maintaining its chromatinized episomes within the nucleus. We have previously shown that cellular factor Poly [ADP-ribose] polymerase 1 (PARP1) binds the EBV genome, stabilizes CTCF binding at specific loci, and that PARP1 enzymatic...

Abstract Beyond their pulmonary disease, many COVID-19 patients experience a complex constellation of characteristics, including hyperinflammatory responses, autoimmune disorders, and coagulopathies. However, the pathogenesis of these aspects of COVID-19 is obscure. More than 90% of people are...

Highlights • Adolescents with CFS report cognitive difficulties. • Adolescents with CFS report more cognitive difficulties than those with CF. • There were no impairments in objective measures of cognitive function. Abstract Objective Cognitive difficulties are among the most disruptive and...

Saliva antibody-fingerprint of reactivated latent viruses after mild/asymptomatic COVID-19 is unique in patients with myalgic-encephalomyelitis/chronic fatigue syndrome Eirini Apostolou, Muhammad Rizwan, Petros Moustardas, Per Sjögren, Bo Christer Bertilson, Björn Bragée, Olli Polo and Anders...