ebv

Now published - see here ***** An HERV-W ENV transcription in atypical memory B cells linked to COVID-19 evolution and risk for long COVID can express the encoded protein from a ribosome readthrough of mRNA from chromosome X. Joanna Brunel; Julien Paganini; Melissa Galloux; Benjamin Charvet...

Abstract Epstein–Barr virus (EBV) infection can engender severe B cell lymphoproliferative diseases1,2. The primary infection is often asymptomatic or causes infectious mononucleosis (IM), a self-limiting lymphoproliferative disorder3. Selective vulnerability to EBV has been reported in...

Abstract Background Epstein-Barr virus (EBV) is a likely prerequisite for multiple sclerosis (MS) but the underlying mechanisms are unknown. We investigated antibody and T cell responses to EBV in persons with MS (pwMS), healthy EBV-seropositive controls (HC) and post-infectious mononucleosis...

Circulating microaggregates as biomarkers for the Post‐COVID syndrome Hermann; Lisch; Gerth; Wick; Fries; Wick CoVID-19 can develop into Post-COVID syndrome of potentially high morbidity, with procoagulation and reactivation of dormant viral infections being hypothesized pathophysiological...

Free: https://www.medrxiv.org/content/10.1101/2024.05.17.24307333v1 Predictors of Postviral Symptoms Following Epstein-Barr Virus-Associated Infectious Mononucleosis in Young People - Data from the IMMUC Study Maren Bodenhausen, Jonas Geisperger, Julia Lange de Luna, Johannes Wendl, Alexander...

https://www.hindawi.com/journals/crig/2024/6475425/ Full title: Mitochondrial DNA Missense Mutations ChrMT: 8981A > G and ChrMT: 6268C > T Identified in a Caucasian Female with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Triggered by the Epstein–Barr Virus Abstract Myalgic...

Sex differences in symptomatology and immune profiles of Long COVID Julio Silva; Takehiro Takahashi; Jamie Wood; Peiwen Lu; Sasha Tabachnikova; Jeffrey Gehlhausen; Kerrie Greene; Bornali Bhattacharjee; Valter Silva Monteiro; Carolina Lucas; Rahul Dhodapkar; Laura Tabacof; Mario Pena-Hernandez...

Expanded T lymphocytes in the cerebrospinal fluid of multiple sclerosis patients are specific for Epstein-Barr-virus-infected B cells Significance On average, 13% of the T lymphocytes in the cerebrospinal fluid of people with the first symptoms of multiple sclerosis are specific for autologous...

Sequential activation of DNA viruses by the RNA virus SARS-CoV-2 in patients with long COVID syndrome Gyongyosi, M; Hasimbegovic, E; Lukovic, D; Zlabinger, K; Spannbauer, A; Samaha, E; Bergler-Klein, J; Hengstenberg, C; Mucher, P; Haslacher, H; Breuer, M; Strassl, R; Riesenhuber, M; Nitsche, C...

Epstein-Barr virus reactivation is not causative for post-COVID-19-syndrome in individuals with asymptomatic or mild SARS-CoV-2 disease course Hoeggerl, Alexandra Domnica; Nunhofer, Verena; Lauth, Wanda; Badstuber, Natalie; Held, Nina; Zimmermann, Georg; Grabmer, Christoph; Weidner, Lisa...

I wasn't sure what prefix to use given that the paper has been accepted in Cell but not published. I read about it in a paywalled news article as the abstract was presented at the ECTRIMS 2023. Ineffective Immune Control of Epstein-Barr Virus-Induced Autoreactive Responses is an Important Cause...

Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID? Abstract Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID (LC) are characterized by similar immunological alterations, persistence of chronic viral infection...

Lymph node targeted multi-epitope subunit vaccine promotes effective immunity to EBV in HLA-expressing mice Dasari, Vijayendra; McNeil, Lisa K.; Beckett, Kirrilee; Solomon, Matthew; Ambalathingal, George; Thuy, T. Le; Panikkar, Archana; Smith, Caitlyn; Steinbuck, Martin P.; Jakubowski, Aniela...

Preprint. Now published see post #6 Abstract Background: Infectious mononucleosis, caused by the Epstein-Barr Virus (EBV-IM), has been linked to the development of myalgic encephalomyelitis/chronic fatigue-syndrome (ME/CFS) in children, adolescents, and young adults. Our study presents the...

Are the integrin binding motifs within SARS CoV-2 spike protein and MHC class II alleles playing the key role in COVID-19? Gerencer, Marijan; McGuffin, Liam J. The previous studies on the RGD motif (aa403-405) within the SARS CoV-2 spike (S) protein receptor binding domain (RBD) suggest that...

Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus Mickaël Bouvet; Stefanie Voigt; Takanobu Tagawa; Manuel Albanese; Yen-Fu Adam Chen; Yan Chen; Devin N. Fachko; Dagmar Pich; Christine Göbel; Rebecca L. Skalsky; Wolfgang...

Association Between Time Spent Outdoors and Risk of Multiple Sclerosis Prince Sebastian; Nicolas Cherbuin; Lisa F. Barcellos; Shelly Roalstad; Charles Casper; Janace Hart; Gregory S. Aaen; Lauren Krupp; Leslie Benson; Mark Gorman; Meghan Candee; Tanuja Chitnis; Manu Goyal; Benjamin Greenberg...

Abstract Myalgic Encephalomyelitis/ Chronic Fatigue syndrome (ME/CFS) is a complex, debilitating, long-term illness without a diagnostic biomarker. ME/CFS patients share overlapping symptoms with long COVID patients, an observation which has strengthened the infectious origin hypothesis of...

Highlights COVID-19 patients have increased incidence of Epstein-Barr Virus reactivation. Detection of EBV DNA is greater among COVID-19 positive patients (27.1% vs 12.5%). No statistical difference in CRP levels of COVID-19 positive vs. negative patients. No statistical difference in...

Cardiovascular involvement is an uncommon but severe complication of Epstein–Barr virus (EBV) infection caused by direct damage and immune injury. Recently, it has drawn increasing attention due to its dismal prognosis. It can manifest in various ways, including coronary artery dilation (CAD)...