ebv

Abstract Post-acute sequelae of COVID-19 (PASC) is a complex and multifaceted clinical challenge requiring to emphasize its underlying pathophysiological mechanisms. This study assessed hundreds of virological, serological, immunological, and tissue damage biomarkers in two patient cohorts who...

Highlights Epstein-Barr virus (EBV) is the first identified oncogenic virus. Globally, 1.5 % of human malignancies are attributed to EBV EBV is associated with lymphomas, carcinomas, and auto-immune diseases. Epstein-Barr Nuclear Antigen 1 (EBNA-1) is a key player in EBV-induced diseases...

Abstract COVID-19 vaccines have prevented millions of COVID-19 deaths. Yet, a small fraction of the population reports a chronic debilitating condition after COVID-19 vaccination, often referred to as post- vaccination syndrome (PVS). To explore potential pathobiological features associated with...

Now published - link here ************* Preprint Full title: Reactivated EBV, HHV6, HAdV in Sputum from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients: Are autoAbs to IFN-I Impairing Antiviral Immunity? https://www.preprints.org/manuscript/202502.0185/v1 Abstract An exhausted...

Now published, see post #5 ------------------ Abstract: Background: Epstein-Barr virus (EBV) infection is a known trigger and risk factor for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-COVID syndrome (PCS). In previous studies, we found enhanced IgG reactivity to EBV...

Abstract Background and Objectives There is a strong link between Epstein-Barr virus (EBV) and multiple sclerosis (MS), but the underlying mechanisms are unclear. Patients with MS typically have a polyspecific intrathecal production of immunoglobulin G (IgG), part of which is directed against...

Antibody responses to Epstein-Barr virus, human herpesvirus 6 and human herpesvirus 7 in patients with chronic fatigue syndrome T Sairenji, K Yamanishi, Y Tachibana, G Bertoni, T Kurata Abstract To test for an association between chronic fatigue syndrome (CFS) and infections with Epstein-Barr...

Detection of herpes viruses in patients with myalgic encephalomyelitis /chronic fatigue syndrome in Belarus Svetlana Orlova, Galina Rudjko, Olga Orlova, Tatsiana Dakukina Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifactorial chronic disease. The etiology and...

Lights and Shadows of Long COVID: Are Latent Infections the Real Hidden Enemy? Francesca Serapide, Marisa Talarico, Salvatore Rotundo, Vittorio Pascale, Riccardo Serraino, Enrico Maria Trecarichi, Alessandro Russo Abstract Long COVID-19 (LC) is a poorly understood, multifactorial condition...

In summary, we report that MS patients are hallmarked by an accumulation of immune responses specifically directed against EBV EBNA381–452 and cross-reacting with CNS GlialCAM370–389–, CRYAB2–21–, MBP205–224–, and ANO2135–154–derived epitopes. Although, our findings provide additional insights...

Effect of high dose vitamin C on Epstein-Barr viral infection Nina A Mikirova, Ronald Hunninghake Background Many natural compounds were tested for the ability to suppress viral replication. The present manuscript details an analysis of high dose vitamin C therapy on patients with EBV...

Exploring common pathogenic association between Epstein Barr virus infection and long-COVID by integrating RNA-Seq and molecular dynamics simulations Kanwal, Ayesha; Zhang, Zhiyong The term "Long-COVID" (LC) is characterized by the aftereffects of COVID-19 infection. Various studies have...

High Somatization Rates, Frequent Spontaneous Recovery, and a Lack of Organic Biomarkers in Post-Covid-19 Condition Anna Tröscher; Patrick Gebetsroither; Marc Rindler; Vincent Böhm; Rainer Dormann; Tim von Oertzen; Anna Heidbreder; Raimund Helbok; Judith Wagner INTRODUCTION Many patients report...

Now published - see here ***** An HERV-W ENV transcription in atypical memory B cells linked to COVID-19 evolution and risk for long COVID can express the encoded protein from a ribosome readthrough of mRNA from chromosome X. Joanna Brunel; Julien Paganini; Melissa Galloux; Benjamin Charvet...

Abstract Epstein–Barr virus (EBV) infection can engender severe B cell lymphoproliferative diseases1,2. The primary infection is often asymptomatic or causes infectious mononucleosis (IM), a self-limiting lymphoproliferative disorder3. Selective vulnerability to EBV has been reported in...

Abstract Background Epstein-Barr virus (EBV) is a likely prerequisite for multiple sclerosis (MS) but the underlying mechanisms are unknown. We investigated antibody and T cell responses to EBV in persons with MS (pwMS), healthy EBV-seropositive controls (HC) and post-infectious mononucleosis...

Circulating microaggregates as biomarkers for the Post‐COVID syndrome Hermann; Lisch; Gerth; Wick; Fries; Wick CoVID-19 can develop into Post-COVID syndrome of potentially high morbidity, with procoagulation and reactivation of dormant viral infections being hypothesized pathophysiological...

Free: https://www.medrxiv.org/content/10.1101/2024.05.17.24307333v1 Predictors of Postviral Symptoms Following Epstein-Barr Virus-Associated Infectious Mononucleosis in Young People - Data from the IMMUC Study Maren Bodenhausen, Jonas Geisperger, Julia Lange de Luna, Johannes Wendl, Alexander...

https://www.hindawi.com/journals/crig/2024/6475425/ Full title: Mitochondrial DNA Missense Mutations ChrMT: 8981A > G and ChrMT: 6268C > T Identified in a Caucasian Female with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Triggered by the Epstein–Barr Virus Abstract Myalgic...

Sex differences in symptomatology and immune profiles of Long COVID Julio Silva; Takehiro Takahashi; Jamie Wood; Peiwen Lu; Sasha Tabachnikova; Jeffrey Gehlhausen; Kerrie Greene; Bornali Bhattacharjee; Valter Silva Monteiro; Carolina Lucas; Rahul Dhodapkar; Laura Tabacof; Mario Pena-Hernandez...