cytokines

  1. sometexan84

    Interferon-Lambda: A Potent Regulator of Intestinal Viral Infections, 2017, Lee and Baldridge

    Abstract Interferon-lambda (IFN-λ) is a recently described cytokine found to be of critical importance in innate immune regulation of intestinal viruses. Endogenous IFN-λ has potent antiviral effects and has been shown to control multiple intestinal viruses and may represent a factor that...
  2. Hoopoe

    Immunological dysfunction persists for 8 months following initial mild-moderate SARS-CoV-2 infection, 2021, Phetsouphanh et al

    Preprint Abstract A proportion of patients surviving acute COVID-19 infection develop post-COVID syndrome (long COVID) encompassing physical and neuropsychiatric symptoms lasting longer than 12 weeks. Here we studied a prospective cohort of individuals with long COVID (the ADAPT study) compared...
  3. B

    USA: InCellDx Dr Patterson - New lab service offering cytokine tests to Covid longhaulers

    This US lab service claims to have great success diagnosing long covid patients and successfully treating them. They offer a lab assay of interleukins and cytokines. It’s not clear which are offered. The literature is not yet published. https://covidlonghaulers.com/ interview with the founder...
  4. Wyva

    Cytokine networks analysis uncovers further differences between those who develop ME/CFS following infectious mononucleosis, 2021, Jason et al

    ABSTRACT Background We followed college students before, during, and after infectious mononucleosis (IM) for the development of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Aim We used network analysis to study relationships between pre-illness cytokine data amongst three...
    • Wyva
    • Thread
    • 2021 cytokines ebv glandular fever infectious mononucleosis leonard jason me/cfs network paper
    • Replies: 3
    • Forum: ME/CFS research
  5. Ryan31337

    Inflammatory Biomarkers in [POTS] with Elevated G-Protein-Coupled Receptor Autoantibodies, 2021, Gunning, Grubb et al

    Open access, https://www.mdpi.com/2077-0383/10/4/623/htm
  6. John Mac

    Risks for Developing ME/CFS in College Students Following Infectious Mononucleosis: A Prospective Cohort Study, 2020, Jason et al

    Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) involves severe fatigue, unrefreshing sleep, and cognitive impairment, leading to functional difficulties; prior studies have not evaluated risk factors with behavioral and immune data collected prior to developing...
    • John Mac
    • Thread
    • aetiology cytokines ebv infectious mononucleosis leonard jason me/cfs no link with pre-existing mental illness pathogenesis psychological young people
    • Replies: 52
    • Forum: ME/CFS research
  7. leokitten

    Can’t or Won’t? Immunometabolic Constraints on Dopaminergic Drive. Treadway MT et al. Trends Cogn Sci. (2019)

    Interesting review of research on the impact of inflammation on the dopamine system as well as a theoretical model and computational method trying to connect it all. Could be a hypothesis as to why Abilify and dopaminergic agents have some partial efficacy in ME, even if it is temporary (so...
  8. Dolphin

    A Cytokine-based model for the pathophysiology of Long COVID symptoms, 2020, Low et al

    This contains quite a lot of discussion of ME/CFS, including in the abstract.
    • Dolphin
    • Thread
    • 2020 cytokines low neuroinflammation paper post infection post-covid
    • Replies: 4
    • Forum: Long Covid research
  9. Kalliope

    Cytokine profiling of extracellular vesicles isolated from plasma in ME/CFS: a pilot study, 2020, Giloteaux, Levine, Hanson et al

    Cytokine profiling of extracellular vesicles isolated from plasma in myalgic encephalomyelitis/chronic fatigue syndrome: a pilot study Ludovic Giloteaux, Adam O'Neal, Jesús Castro-Marrero, Susan M. Levine & Maureen R. Hanson Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)...
    • Kalliope
    • Thread
    • 2020 cytokines extracellular vesicles giloteaux levine maureen hanson me/cfs paper susan levine
    • Replies: 7
    • Forum: ME/CFS research
  10. J

    BDNF reverses aging-related microglial activation, Wu et al. 2020

    https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-020-01887-1
  11. Andy

    The role of IP‐10 in Chronic Fatigue Syndrome, 2018, McArdle et al

    Couldn't find this one on the forum already. Abstract only, https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.31.1_supplement.lb789 Published in FASEB Journal, Special Issue:Experimental Biology 2017 Meeting Abstracts, https://faseb.onlinelibrary.wiley.com/toc/15306860/2017/31/S1
    • Andy
    • Thread
    • 2018 chalder fatigue scale cytokines ip-10 mcardle me/cfs paper
    • Replies: 3
    • Forum: ME/CFS research
  12. John Mac

    Discriminatory cytokine profiles predict muscle function, fatigue and cognitive function in patients with ME/CFS. McArdle et al. 2020

    Full Title: Discriminatory cytokine profiles predict muscle function, fatigue and cognitive function in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) https://www.medrxiv.org/content/10.1101/2020.08.17.20164715v1?rss=1 This was a study I took part in. Papers from...
  13. Andy

    Curcumin Improves Delayed Onset Muscle Soreness and Postexercise Lactate Accumulation, 2020, Mallard et al

    Open access, https://www.tandfonline.com/doi/full/10.1080/19390211.2020.1796885
  14. Anna H

    Sweden planned study: Cell biological/Immunometabolic changes in myalgic encephalomyelitis, ME, Rosén et al (MECELL)

    Professor Anders Rosén and Eirini Apostolou, PhD, at Linköping University are planning a study consisting of 3 subprojects, looking at cytokines, EBV enzyme, antibodies and reactivated retro virus etc in blood and saliva samples from 200 mild, moderate and severe ME patients and 200 controls...
    • Anna H
    • Thread
    • antibodies covid-19 cytokines dna ebv mecell retrovirus rosen sweden
    • Replies: 18
    • Forum: ME/CFS research news
  15. Kalliope

    MCP-1 is Increased in Patients with CFS and FM, whilst several other immune markers are significantly lower than healthy controls, 2020, Groven et al

    Elsevier - Brain, Behaviour, & Immunity - Health MCP-1 is Increased in Patients with CFS and FM, whilst several other immune markers are significantly lower than healthy controls - Nina Groven, Egil Andreas Fors, Astrid Kamilla Stunes, Solveig Klæbo Reitan Abstract The role of the immune system...
    • Kalliope
    • Thread
    • 2020 cytokines fibromyalgia groven il-10 il-6 mcp-1 me/cfs paper tgf-β
    • Replies: 3
    • Forum: ME/CFS research
  16. Dolphin

    Role of immune responses, focussing on herpes virus specificity and interferon-gamma, in Myocardial Infarction with reperfusion & in CFS, 2019, Murali

    • Dolphin
    • Thread
    • 2019 cmv cytokines ebv herpesvirus me/cfs murali myocardial paper t cells
    • Replies: 0
    • Forum: ME/CFS research
  17. Sly Saint

    Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations - [new article 2020]

    Basal glycolysis is reduced in ME/CFS CD4+ T cells. https://www.jci.org/articles/view/132185/figure/4 paper from December 2019 https://www.jci.org/articles/view/132185 new Article by Mady Hornig https://www.jci.org/articles/view/134985
    • Sly Saint
    • Thread
    • 2020 article cytokines glycolysis hornig me/cfs metabolism paper t cells
    • Replies: 5
    • Forum: ME/CFS research
  18. T

    The role of low-grade inflammation in ME/CFS (Chronic Fatigue Syndrome) - associations with symptoms, 2019, Jonsjö et al

    https://www.sciencedirect.com/science/article/abs/pii/S0306453019313198
    • Tom Kindlon
    • Thread
    • 2019 b-ngf ccl11 cxcl10 cytokines inflammation jonsjo me/cfs paper tgf-β tnf
    • Replies: 41
    • Forum: ME/CFS research
  19. R

    ME/CFS patients exhibit altered T cell metabolism and cytokine associations (2019) Mandarano, Hanson et al

    https://www.nih.gov/news-events/news-releases/study-finds-differences-energy-use-immune-cells-me/cfs New findings published in the Journal of Clinical Investigation suggest that specific immune T cells from people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) show disruptions...
    • Ron
    • Thread
    • cornell university cytokines immune challenge immunology mandarano maureen hanson me/cfs t-cells
    • Replies: 28
    • Forum: ME/CFS research
  20. Sly Saint

    Fatigue severity in anti-nuclear antibody-positive individuals does not correlate with pro-inflammatory cytokine levels..., 2019, Hafiz et al

    Fatigue severity in anti-nuclear antibody-positive individuals does not correlate with pro-inflammatory cytokine levels or predict imminent progression to symptomatic disease Waleed Hafiz, Rawad Nori, Ariana Bregasi, Babak Noamani, Dennisse Bonilla, Larissa Lisnevskaia, Earl Silverman, Arthur...
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