autoantibodies

Discovery of functionally distinct anti-C7 monoclonal antibodies and stratification of anti-nicotinic AChR positive Myasthenia Gravis patients Lekova, Eleonora; Zelek, Wioleta M.; Gower, David; Spitzfaden, Claus; Osuch, Isabelle H.; John-Morris, Elen; Stach, Lasse; Gormley, Darren; Sanderson...

Please see below information about Dr Goebel’s inaugural lecture on the 27th of November 6pm – see details below this email. This can be accessed virtually and will be recorded to watch afterwards too. The lecture itself starts at 6pm. From ilcamsevents: ilcamsevents@liverpool.ac.uk Dear...

Brain-targeted autoimmunity is strongly associated with Long COVID and its chronic fatigue syndrome as well as its affective symptoms. Abstract Background: Autoimmune responses contribute to the pathophysiology of Long COVID, affective symptoms and myalgic encephalomyelitis/chronic fatigue...

Examination of autoantibodies to type I interferon in patients suffering from long COVID Kristoffer Skaalum Hansen; Sofie Eg Jørgensen; Morten Kelder Skouboe; Jane Agergaard; Berit Schiøttz-Christensen; Line Khalidan Vibholm; Martin Tolstrup; Lars Østergaard; Steffen Leth; Trine H. Mogensen...

Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors Abstract Background The Long-COVID syndrome constitutes a plethora of persisting symptoms with neurological disorders being the most...

Full title: Anti-satellite glia cell IgG antibodies in fibromyalgia patients are related to symptom severity and to metabolite concentrations in thalamus and rostral anterior cingulate cortex Highlights FMS have higher anti-SGC IgG levels compared to healthy controls. FMS with high, compared...

Scheibenbogen et al Abstract There is increasing evidence for an autoimmune aetiology in post-infectious Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). SARS-CoV-2 has now become the main trigger for ME/CFS. We have already conducted two small proof-of-concept studies of IgG...

Generation of potentially inhibitory autoantibodies to ADAMTS13 in coronavirus disease 2019 Doevelaar, Adrian A. N.; Bachmann, Martin; Hölzer, Bodo; Seibert, Felix S.; Rohn, Benjamin J.; Zgoura, Panagiota; Witzke, Oliver; Dittmer, Ulf; Brenner, Thorsten; Paniskaki, Krystallenia; Yilmaz, Serap...

https://classic.clinicaltrials.gov/ct2/show/NCT05643794?recrs=abdf&type=Intr&cond=Fibromyalgia&draw=3&rank=11 Someone is moving ahead with the theory of autoimmune antibodies for fibromyalgia

Now published, see post #6. Preprint, not peer reviewed : https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4332223 Autoantibodies to Selenoprotein P in Patients with Chronic Fatigue Syndrome suggest Selenium Transport Impairment and Acquired Resistance to Thyroid Hormone Qian Sun1,2,†...

Full title: Clinical improvement of Long-COVID is associated with reduction in autoantibodies, lipids, and inflammation following therapeutic apheresis Abstract In the aftermath of the COVID-19 pandemic, we are witnessing an unprecedented wave of post-infectious complications. Most...

An old study that has been included in a list of studies finding issues with G protein-coupled receptors. https://pubmed.ncbi.nlm.nih.gov/12851722/. Paywall Abstract The disturbance of the central nervous system and immunological abnormalities have been suggested in patients with chronic...

Abstract Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse symptoms, which can persist for months. While antiviral antibodies are protective, those targeting interferons and other immune factors are associated with adverse coronavirus disease 2019 (COVID-19)...

Immune adsorption for the treatment of fatigue-dominant long-/post-COVID syndrome—a case series of standardized individual experimental therapy Research letter / case series of 10 patients. Announced English version not published yet. So in lieu of an abstract here's a google translate link...

https://www.frontiersin.org/articles/10.3389/fneur.2023.1137958/full Open access Team from Kagoshima, Japan Objective: Autoimmune autonomic ganglionopathy (AAG) is a rare disorder characterized by autonomic failure associated with the presence of anti-ganglionic acetylcholine receptor (gAChR)...

Autoantigen profiling reveals a shared post-COVID signature in fully recovered and Long COVID patients Multiple authors from UCSF Some individuals do not return to baseline health following SARS-CoV-2 infection, leading to a condition known as Long COVID. The underlying pathophysiology of Long...

Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity Briquez PS, Rouhani SJ, Yu J, Pyzer AR, Trujillo J, Dugan HL, Stamper CT, Changrob S, Sperling AI, Wilson PC, Gajewski TF, Hubbell JA, Swartz MA Patients infected...

Most patients with Post COVID Syndrome (PCS) present with a plethora of symptoms without clear evidence of organ dysfunction. A subset of them fulfills diagnostic criteria of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Symptom severity of ME/CFS correlates with natural...

Abstract Background Autoimmunity has been reported in patients with severe COVID-19. We investigated whether antinuclear/extractable-nuclear antibodies (ANAs) were present up to a year after infection, and if they were associated with the development of clinically relevant Post-Acute Sequalae...

Summary Background Understanding how SARS-CoV-2 affects respiratory centres in the brainstem may help to preclude assisted ventilation for patients in intensive care setting. Viral invasion appears unlikely, although autoimmunity has been implicated, the responsible antigens remain unknown. We...