autoantibodies

Objective: The long-lasting persistence of autoantibodies stands as one of the hypotheses explaining the multisystemic manifestations seen in individuals with post-COVID-19 condition. The current review offers restricted insights into the persistence of autoantibodies in plasma/serum in people...

A causal link between autoantibodies and neurological symptoms in long COVID Abstract Acute SARS-CoV-2 infection triggers the generation of diverse and functional autoantibodies (AABs), even after mild cases. Persistently elevated autoantibodies have been found in some individuals with long...

Now published - link here Preprint Prevalent and persistent new-onset autoantibodies in mild to severe COVID-19 Abstract Autoantibodies have been shown to be implied in COVID-19 but the emerging autoantibody repertoire remains largely unexplored. We investigated the new-onset autoantibody...

https://pubmed.ncbi.nlm.nih.gov/37147113/ Abstract Objective: Identify autoantibodies in anti-Ro/SS-A negative primary Sjögren's syndrome (SS). Methods: This is a proof-of-concept, case-control study of SS, healthy (HC) and other disease (OD) controls. A discovery dataset of plasma samples...

Discovery of functionally distinct anti-C7 monoclonal antibodies and stratification of anti-nicotinic AChR positive Myasthenia Gravis patients Lekova, Eleonora; Zelek, Wioleta M.; Gower, David; Spitzfaden, Claus; Osuch, Isabelle H.; John-Morris, Elen; Stach, Lasse; Gormley, Darren; Sanderson...

Please see below information about Dr Goebel’s inaugural lecture on the 27th of November 6pm – see details below this email. This can be accessed virtually and will be recorded to watch afterwards too. The lecture itself starts at 6pm. From ilcamsevents: ilcamsevents@liverpool.ac.uk Dear...

Brain-targeted autoimmunity is strongly associated with Long COVID and its chronic fatigue syndrome as well as its affective symptoms. Abstract Background: Autoimmune responses contribute to the pathophysiology of Long COVID, affective symptoms and myalgic encephalomyelitis/chronic fatigue...

Examination of autoantibodies to type I interferon in patients suffering from long COVID Kristoffer Skaalum Hansen; Sofie Eg Jørgensen; Morten Kelder Skouboe; Jane Agergaard; Berit Schiøttz-Christensen; Line Khalidan Vibholm; Martin Tolstrup; Lars Østergaard; Steffen Leth; Trine H. Mogensen...

Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors Abstract Background The Long-COVID syndrome constitutes a plethora of persisting symptoms with neurological disorders being the most...

Full title: Anti-satellite glia cell IgG antibodies in fibromyalgia patients are related to symptom severity and to metabolite concentrations in thalamus and rostral anterior cingulate cortex Highlights FMS have higher anti-SGC IgG levels compared to healthy controls. FMS with high, compared...

Scheibenbogen et al Abstract There is increasing evidence for an autoimmune aetiology in post-infectious Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). SARS-CoV-2 has now become the main trigger for ME/CFS. We have already conducted two small proof-of-concept studies of IgG...

Generation of potentially inhibitory autoantibodies to ADAMTS13 in coronavirus disease 2019 Doevelaar, Adrian A. N.; Bachmann, Martin; Hölzer, Bodo; Seibert, Felix S.; Rohn, Benjamin J.; Zgoura, Panagiota; Witzke, Oliver; Dittmer, Ulf; Brenner, Thorsten; Paniskaki, Krystallenia; Yilmaz, Serap...

https://classic.clinicaltrials.gov/ct2/show/NCT05643794?recrs=abdf&type=Intr&cond=Fibromyalgia&draw=3&rank=11 Someone is moving ahead with the theory of autoimmune antibodies for fibromyalgia

Now published, see post #6. Preprint, not peer reviewed : https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4332223 Autoantibodies to Selenoprotein P in Patients with Chronic Fatigue Syndrome suggest Selenium Transport Impairment and Acquired Resistance to Thyroid Hormone Qian Sun1,2,†...

Full title: Clinical improvement of Long-COVID is associated with reduction in autoantibodies, lipids, and inflammation following therapeutic apheresis Abstract In the aftermath of the COVID-19 pandemic, we are witnessing an unprecedented wave of post-infectious complications. Most...

An old study that has been included in a list of studies finding issues with G protein-coupled receptors. https://pubmed.ncbi.nlm.nih.gov/12851722/. Paywall Abstract The disturbance of the central nervous system and immunological abnormalities have been suggested in patients with chronic...

Abstract Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse symptoms, which can persist for months. While antiviral antibodies are protective, those targeting interferons and other immune factors are associated with adverse coronavirus disease 2019 (COVID-19)...

Immune adsorption for the treatment of fatigue-dominant long-/post-COVID syndrome—a case series of standardized individual experimental therapy Research letter / case series of 10 patients. Announced English version not published yet. So in lieu of an abstract here's a google translate link...

https://www.frontiersin.org/articles/10.3389/fneur.2023.1137958/full Open access Team from Kagoshima, Japan Objective: Autoimmune autonomic ganglionopathy (AAG) is a rare disorder characterized by autonomic failure associated with the presence of anti-ganglionic acetylcholine receptor (gAChR)...

Autoantigen profiling reveals a shared post-COVID signature in fully recovered and Long COVID patients Multiple authors from UCSF Some individuals do not return to baseline health following SARS-CoV-2 infection, leading to a condition known as Long COVID. The underlying pathophysiology of Long...