Long COVID-related blood-brain barrier breakdown and microstructure in older adults are modified by sex and Alzheimer’s disease genetic risk
Emilie T. Reas, Austin Alderson-Myers, Seraphina K. Solders, Qian Shen, Charlotte S. Rivera, Xin Wang, Jordan Stiver, Sarah J. Banks, Jennifer S. Graves...
Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions
Christina Dardani, Jamie W. Robinson, Hannah J. Jones, Dheeraj Rai, Evie Stergiakouli, Jakob Grove, Renee Gardner, Andrew M. McIntosh, Alexandra Havdahl, Gibran...
New blog post about fraud and research misconduct in scientific research.
https://mecfsskeptic.com/how-many-scientific-papers-are-fake/
Twitter summary:
1) How many scientific papers are fake?
A new review argues that fabrication and falsification of scientific results may be more common...
Environmental pesticide exposure and Alzheimer's disease in southern Spain: A cross-sectional study
Cristofer Ruiz-González, Pablo Román, Lola Rueda-Ruzafa, Diana Cardona, Mar Requena, Raquel Alarcón
Abstract
The intensive cultivation under plastic in southern Spain has made the agricultural...
Alzheimer's disease-associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain
https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.14401
Abstract
INTRODUCTION
While there may be microbial contributions to...
Impaired glymphatic function as a biomarker for subjective cognitive decline: An exploratory dual cohort study
Yuxia Li, Luyao Wang, Jiayi Zhong, Huanyu Xu, Ying Han, Chuantao Zuo, Jiehui Jiang
Background: Subjective cognitive decline (SCD) has been recognized as a potential risk stage for...
Parallel electrophysiological abnormalities due to COVID-19 infection and to Alzheimer's disease and related dementia
Yang Jiang; Jennifer Neal; Pradoldej Sompol; Görsev Yener; Xianghong Arakaki; Christopher M. Norris; Francesca R. Farina; Agustin Ibanez; Susanna Lopez; Abdulhakim Al-Ezzi; Voyko...
Alzheimer’s scientist indicted for allegedly falsifying data in $16M scheme
A federal grand jury has indicted an embattled Alzheimer's researcher for allegedly falsifying data to fraudulently obtain $16 million in federal research funding from the National Institutes of Health for the...
Highlights
•
Improvement from post-COVID-19 cognitive impairment (CI) is slow
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Post-COVID-19 CI is molecularly distinct from Alzheimer’s disease
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Post-COVID-19 CI is associated with CSF monocyte recruitment and gene alterations
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Improvement from post-COVID-19 CI is linked to greater CSF...
Microfluidic Isolation of Neuronal-Enriched Extracellular Vesicles Shows Distinct and Common Neurological Proteins in Long COVID, HIV Infection and Alzheimer’s Disease
Pulliam, Lynn; Sun, Bing; McCafferty, Erin; Soper, Steven A.; Witek, Malgorzata A.; Hu, Mengjia; Ford, Judith M.; Song, Sarah...
Plasma proteomic evidence for increased Alzheimer's disease-related brain pathology after SARS-CoV-2 infection
Eugene P Duff; Henrik Zetterberg; Amanda Heslegrave; Abbas Dehghan; Paul Elliott; Naomi Allen; Heiko Runz; Rhiannon Laban; Elena Veleva; Christopher D Whelan; Benjamin B Sun; Paul M...
Similar to doing an MOT on a car, scientists believe they can run a blood test to check how fast a person's internal organs are ageing, and even predict which ones might soon fail.
The Stanford University team say they can monitor 11 major body parts, including the heart, brain and lungs.
They...
Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis
https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awad303/7308687
Brain, awad303, https://doi.org/10.1093/brain/awad303
Published: 18 October 2023
Abstract
Alzheimer’s disease is a...
Severe acute respiratory syndrome coronavirus 2 infection leads to Tau pathological signature in neurons
Abstract
COVID-19 has represented an issue for global health since its outbreak in March 2020. It is now evident that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...
Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics
Petersen, Mark A.; Ryu, Jae Kyu; Akassoglou, Katerina
The blood coagulation protein fibrinogen is deposited in the brain in a wide range of neurological diseases and traumatic injuries with blood–brain barrier (BBB)...
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