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Rituximab: what recovery level is possible?

Discussion in 'Rituximab' started by Perrier, Nov 9, 2017.

  1. Perrier

    Perrier Established Member

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    Having heard only sporadic stories in the media, I'm wondering if anyone has information about the kind of recovery Fluge and Mella saw.

    1) how many were able to go back to pre-disease level of life? Working, exercising, etc.

    2) what became possible for the majority of patients?
     
  2. Esther12

    Esther12 Senior Member (Voting Rights)

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    It's probably worth waiting for the release of results for the multi-centre RCT (which they're just analysing now, and should be released next spring). There have been reports of individuals reporting full recovery... but it could be that was unrelated to their use of rituximab.

    Fingers crossed. The anecdotal evidence we've had over the last few years has been pretty mixed, and not as positive as you'd expect if it was that the majority of patients gained a major improvement in health, but it's hard to say. Hopefully, if there is a positive result for the RCT, they will be able to work out how to objectively identify those patients most likely to benefit in advance of treatment.
     
  3. Jan

    Jan Senior Member (Voting Rights)

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    We are all pretty desperate to find this out but it seems we have to wait until next year.
     
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  4. Perrier

    Perrier Established Member

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    Desperate is the word, indeed!
    But what about the previous two studies. Any info there?
     
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  5. Scarecrow

    Scarecrow Senior Member (Voting Rights)

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  6. Scarecrow

    Scarecrow Senior Member (Voting Rights)

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  7. BurnA

    BurnA Senior Member (Voting Rights)

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    There is a table in one of the previous studies which lists the response of all participants.
    I think it's Table 1 here

    It was fairly mixed, But just read the paper there is a lot of info in it.
     
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  8. Esther12

    Esther12 Senior Member (Voting Rights)

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    Enough positive info that it's worth funding a large trial, and to feel a bit hopeful about it, but it hard to say much more than that.
     
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  9. Gingergrrl

    Gingergrrl Senior Member (Voting Rights)

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    How do you find the "Library" and is it articles that anyone can read? Sorry for another :banghead: question!
     
  10. Scarecrow

    Scarecrow Senior Member (Voting Rights)

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    It's the Science Library in the ME/CFS News and Research sub-forum. Here's a link:

    https://www.s4me.info/index.php?forums/science-library-read-only.67/
    Yes. Free access. No fines for late return.
    No need to apologise. We're all here to help each other!
     
  11. Scarecrow

    Scarecrow Senior Member (Voting Rights)

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    Actually, you might find that some of the links are pay-walled.
     
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