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@Justy , in the link you provided emotional lability is given as an alternative name for pba, although it is noted that this may not be an accurate description. However, emotional lability can be a symptom of ME (off the top of my head, I think CCC mentions it) and it's definitely something...

While there may be something in that, it doesn't tie in with my own experience. I was heading downhill fast and would have been in danger of losing my job if I'd started having multiple absences. It is of course possible that the reversal was spontaneous but I don't believe so. I improved to a...

Very true and it doesn't even have to be saline. I have an odd problem where I become intensely fatigued and then seem to vasodilate quite dramatically and get extreme thirst. A long drink always revives me. One one occasion on holiday I just couldn't force any water down - it was like trying to...

Yes, it's normal to feel worse for a few days after treatment. It felt very much like PEM to me with the increased heart rate to go with it. Why that should lead to an improvement over time is a mystery. I agree that it stretches credibility that somebody would persevere for months.

Presumably, the IV bumps up blood volume more and faster than taking fluid orally but the effect on volume could only be relatively transient. Perhaps it's the consequence of temporarily increased blood volume that doesn't wear off quite so quickly.

Health is a devolved power, so under the control of the Scottish government. Therefore, the Scottish NHS is autonomous. There is nothing to stop good (or bad) practise being adopted by the NHS in other parts of the UK.

This is just a personal perspective but I don't associate depression with fatigue, although it's a little difficult to tell since I already had ME long, long before the depression and I was working full time and permanently fatigued. My depression was of the 'utter gut wrenching despair' kind...

Who among us hasn't had a similar experience? Can't be too many. There was a time I would have agreed with you. Now I'm less certain. A few years ago, I learned that one of my male colleagues had been diagnosed with depression when he was at university. Several months later he got a revised...

Thanks for starting the thread, Woolie. It's worse than I thought. So depression may be an even bigger wastebasket diagnosis than ME/CFS. In another tweet, Fried claims that the reliability of a MDD diagnosis is "barely above chance level". It's enough to make you wonder how any research...

When you put it like that, I'm so much closer to agreeing with you but it is central and important for a proportion.

This link was in one of the subsequent tweets: http://thepsychologist.bps.org.uk/volume-29/january-2016/depression-more-sum-its-symptoms/

Hoping that someone may have a better memory than me. (Yes I do know where I am!) Does anyone recall a recent post, perhaps in the last 2 weeks, which was in relation to B12 and methylation and was in reference to work by Davies and/or Naviaux. It'll be unpublished.

@Jonathan Edwards It does seem that many of us do have problems being upright but there doesn't seem to be an awful lot of consistency in the way that it manifests: some have low blood pressure, others raised; some get outright tachycardia or a 30+ increase in heart rate, others don't; some can...

Can't orthostasis refer to being upright? That is, the trunk is upright regardless of what the legs are doing? On a scale, sitting gives more relief than standing, sitting with feet up is better than feet on the floor, half lying back is better than the trunk being fully upright.

This has only just struck a chord with me. I did a poor man's TTT a few years ago with increased blood pressure and the 30+ increase in heart rate. http://forums.phoenixrising.me/index.php?threads/increased-blood-pressure-during-poor-mans-ttt.31014/ Only the final poster in that thread...

You can't possibly think I'm that stupid. Please read post#180.

@Jonathan Edwards I didn't mean to be misleading. Many have the immediate problem of POTS, too. I have that on rare occasions but is more common for me to have the intolerance eventually rather than sooner - but bear in mind that I'm relatively mildly affected by ME and a lot of pwME wouldn't...

Memes, themselves, are merely an idea. Memetics is hardly a science. Actually, the hypothesis that brain size in primates is linked to monogamy is based on competition among males for a mate, not the preference of females. Sorry but I still can't see how intelligence 'drives' evolution.