1. See the 'News in Brief' from w/c 12th August, by clicking here, Guest.
    Dismiss Notice

Video: Dr. Peter Vadas - CME Presentation: Mast Cells Gone Wild - Mast Cell Activation Disorders

Discussion in 'Immune: Autoimmune and Mast Cell Disorders' started by Liessa, Feb 1, 2019.

  1. Liessa

    Liessa Established Member (Voting Rights)

    Messages:
    35
    Likes Received:
    305
    Dr. Peter Vadas - CME Presentation: Mast Cells Gone Wild - Mast Cell Activation Disorders



    First 20 minutes are an introduction and offsetting MCAS against mastocytosis. After that he focuses on the type of MCAS that overlaps with POTS and EDS, mentioning the following article:

    JJ Lyons et al. Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number. Nature Genetics DOI: 10.1038/ng.3696 (2016).
    https://www.ncbi.nlm.nih.gov/pubmed/27749843

    He also discusses the higher incidence of various autoimmune conditions among these people and considers MCAS could potentially have autoimmune basis as well.
    If that turns out to be the case it would have consequences for treatment, shifting it from symptomatic to targeting the autoimmune process.

    No mention of ME, but potentially interesting for some nevertheless.
     
    shak8, rvallee, Michiel Tack and 3 others like this.

Share This Page