This thread has been split from the conference thread here Prof Alain Moreau presented on the 'Identification of post-exertional dysregulated circulating microRNAs in ME/CFS pathogenesis' See also the MEA Summary page 6. https://www.youtube.com/watch?v=eKbVBcxwt88 Somewhere around the 25 minute mark, Moreau starts talking about a specific micro-RNA that is something to do with CD-20 and he wonders whether having that micro-RNA distinguishes between those who do and don't respond to rituximab. He mentions that he's going to tell Oystein and Fluge about it (which he has presumably done by now). Any thoughts, @Jonathan Edwards? He didn't mention how common it is (and I don't know whether it makes sense to talk about population norms for micro-RNA, given that it's not DNA). It would need to tie in with a response to rituximab for PWME being fairly rare, because if it wasn't, RituxME would have shown positive results.