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Ron Davis: Grant award: Molecular and single-cell immunology in ME/CFS

Discussion in 'ME/CFS research news' started by Indigophoton, Jun 25, 2018.

  1. Sly Saint

    Sly Saint Senior Member (Voting Rights)

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    https://www.youtube.com/watch?v=vZQgJP47kA4



    around 24:00 to 26:00

    eta: he did mention it in more detail at another conference but I can't remember which one.
     
    Inara and adambeyoncelowe like this.
  2. JaimeS

    JaimeS Senior Member (Voting Rights)

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    Ongoing, so far as I'm aware. Beyond saying that the SGTC team is still working on it -- and because they're still working on it -- I shouldn't say anything else. :thumbup:
     
    Inara, mango, Zombie Lurker and 9 others like this.
  3. tuha

    tuha Established Member (Voting Rights)

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    Great to hear that money are comming. I think with The Pineapple Fund donation, OMF, NIH and many donors - Stanford research team will not be far away form the budget 10 mil. USD a year. I think this can really move the research on Stanford. It would be great to have such a team with that budget also in UK. What to do about it?
    I followed some crowdfunding campaigns for research projects in UK (IiME,...) but they were able to get only 100 000 a year, i never understood why so little.
     
  4. Sunshine3

    Sunshine3 Senior Member (Voting Rights)

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    Thats one year....Pine won't be coming in again, they are nowhere near 10 million per year really...
     
  5. Amw66

    Amw66 Senior Member (Voting Rights)

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    I did wonder if this was some form of autoantibody stuck on translocator membranes as postulated by Prof Behan in 1980s .

    There are a lot of interesting studies which got sidetracked after BPS hijacked agenda - which are being rediscovered- eg sticky blood. These are not new phenomena, just forgotten.

    It would be worthwhile trawling past research in pertinent areas- given the technology and processes now available who knows where thus may lead ?
     
    Ash, Jacob Richter, Inara and 10 others like this.
  6. JaimeS

    JaimeS Senior Member (Voting Rights)

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    Still freelancing for Stanford sometimes, and looking into some of those older theories that were never disproved, just... left sitting there, waiting on more money and better interest.
     
  7. mango

    mango Senior Member (Voting Rights)

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    Jacob Richter, Aroa, Inara and 4 others like this.
  8. FMMM1

    FMMM1 Senior Member (Voting Rights)

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    Anyone got an update i.e. when is it due to report? 2018 + 5 years = 2023!
     
  9. FMMM1

    FMMM1 Senior Member (Voting Rights)

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    Happened to be reading this
    Genetic risk factors of ME/CFS: a critical review
    Joshua J Dibble, Simon J McGrath, Chris P Ponting
    And noticed this reference:
    "The MHC locus and genetic susceptibility to autoimmune and infectious diseases"
    29.Matzaraki, V., Kumar, V., Wijmenga, C. and Zhernakova, A. (2017) The MHC locus and genetic susceptibility to autoimmune and infectious diseases Genome Biol.

    So the Stanford study may test whether ME/CFS has a strong MHC/HLA "autoimmune and infectious diseases" link?
     
    Ash, Jacob Richter, janice and 2 others like this.
  10. Sly Saint

    Sly Saint Senior Member (Voting Rights)

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    any chance this could be the WASF3?
     
    FMMM1 likes this.
  11. SNT Gatchaman

    SNT Gatchaman Senior Member (Voting Rights)

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    The paper said —

    So I don't think it would be WASF3 itself, but perhaps instead it's something impairing the ER stress response (via eIF2a) that then induces increased intracellular WASF3.

    (Maybe the upstream mechanism involves one or more microRNAs or circRNAs??)
     
    janice, Sly Saint, Lindberg and 3 others like this.

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