News from the USA, United States of America

Appreciate this heads up, @rvallee. I hadn't seen or put that together yet.

Sharing for sight from the referenced owner, yesterday on X:

https://twitter.com/user/status/1891142334416331216


'The country now faces a huge challenge: to confirm persistence of Covid in our bodies and does it lead to increase in cancer in the young? Can we clear this virus? We must solve this together for the world. This and the cancer vaccine will be my focus.'
 
FYI, @rvallee

9/8/22, Forbes: 'Billionaire-Backed Group Steps Up Hunt For Long Covid Treatment'

'The Long Covid Research Initiative (LCRI) hopes to accelerate efforts to understand and treat Long Covid...'

'LCRI has already secured a commitment for further funding from the Chan Soon-Shiong Family Foundation, led by biotech billionaire Dr. Patrick Soon-Shiong (the final amount has yet to be settled)'

9/22/22, Fierce Healthcare: 'A new global collaboration of scientists, clinicians and patients aims to hasten clinical trials on long COVID'

'The Long Covid Research Initiative (LCRI), part of the nonprofit PolyBio Research Foundation, is run by a team of about a dozen volunteers and thus far has amassed a roster of two dozen researchers and clinicians.

'So far, its backers include Balvi, a scientific investment fund that has committed $15 million, and the Chan Soon-Shiong Family Foundation, which has donated an undisclosed amount.'

'What is needed, he believes, is a “next generation” T-cell therapy that can kill contaminated cells, which antibodies do not do.'
 
(lastly, for anyone that wants to go back and watch)

9/18/20, LA Times Studio: '‘Second Opinion,’ Episode 4: The Long-Haulers'

'Our fourth episode examines the long-term health impact of COVID-19 on survivors of the disease. Los Angeles Times Executive Chairman Dr. Patrick Soon-Shiong, a surgeon and scientist, is joined by Dr. Carlos Cordon-Cardo, professor and chair of the Department of Pathology at the Icahn School of Medicine at Mount Sinai.We will also hear from a group of recovering coronavirus patients who continue to suffer from a variety of symptoms months after contracting COVID-19. The discussion is moderated by Eli Stokols of The Times' Washington bureau.'

 
New York Times: 'Scientists Describe Rare Syndrome Following Covid Vaccinations'

'In a small study, patients with the syndrome were more likely to experience reactivation of Epstein-Barr virus and high levels of a coronavirus protein'

'But in a small number of people, the shots may have led to a constellation of side effects that includes fatigue, exercise intolerance, brain fog, tinnitus and dizziness, together referred to as “post-vaccination syndrome,” according to a small new study.’

“I want to emphasize that this is still a work in progress,” said Akiko Iwasaki, an immunologist at Yale University who led the work.

"..it’s the first kind of glimpse at what may be going on within these people.”

'Because the symptoms reported by people with post-vaccination syndrome show considerable overlap with those of long Covid, the researchers also analyzed blood from 134 people with long Covid and 134 healthy controls.'

'Yet the results, from a scientific team known for rigorous work, suggest that post-vaccination syndrome deserves further scrutiny, they said.'

'Dr. Iwasaki and her team found that people with post-vaccination syndrome had significantly higher plasma levels of the coronavirus spike protein than everyone else — including those with long Covid — from 26 to 709 days after receiving the vaccine.’
 
Last edited:
Dakota15 said:
New York Times: 'Scientists Describe Rare Syndrome Following Covid Vaccinations'

'In a small study, patients with the syndrome were more likely to experience reactivation of Epstein-Barr virus and high levels of a coronavirus protein'

'But in a small number of people, the shots may have led to a constellation of side effects that includes fatigue, exercise intolerance, brain fog, tinnitus and dizziness, together referred to as “post-vaccination syndrome,” according to a small new study.’

“I want to emphasize that this is still a work in progress,” said Akiko Iwasaki, an immunologist at Yale University who led the work.

"..it’s the first kind of glimpse at what may be going on within these people.”

'Because the symptoms reported by people with post-vaccination syndrome show considerable overlap with those of long Covid, the researchers also analyzed blood from 134 people with long Covid and 134 healthy controls.'

'Yet the results, from a scientific team known for rigorous work, suggest that post-vaccination syndrome deserves further scrutiny, they said.'

'Dr. Iwasaki and her team found that people with post-vaccination syndrome had significantly higher plasma levels of the coronavirus spike protein than everyone else — including those with long Covid — from 26 to 709 days after receiving the vaccine.’
Click to expand...
Thread on the study:
Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination, 2025, Bhattacharjee et al
 
C&EN: 'Long COVID studies stymied by pharma’s lack of cooperation'

'Academic researchers want to repurpose drugs for the condition. Manufacturers aren’t supplying them'

Avindra Nath believes he has a way to treat certain people with long COVID—or at least shed a light on their condition.

'Nath, a neurologist with the US National Institutes of Health (NIH), wants to use pembrolizumab to try to help improve the conditions of people with long COVID whose T cells may be exhausted. T-cell exhaustion is still poorly understood in long COVID—par for the course with the multifaceted postviral disease that’s now affected more than 400 million people worldwide (Nat. Med. 2024, DOI: 10.1038/s41591-024-03173-6). But some studies have revealed changes in T-cell responses that indicate the immune cells are, at the very least, dysfunctional, which could allow reservoirs of SARS-CoV-2 to persist and cause chronic inflammation (Lancet Infect. Dis. 2025, DOI: 10.1016/S1473-3099(24)00769-2).'

'Pembrolizumab is a checkpoint inhibitor that binds to the protein PD-1 on T cells to help them recognize and attack invaders. It’s better known as Keytruda, the blockbuster drug that earned its manufacturer, Merck & Co., $29.5 billion last year.'

"All the rest we can do ourselves," Nath says. "We just need the drug."

'Nancy Klimas, director of the Institute for Neuro-lmmune Medicine at Nova Southeastern University, says she approached GSK, Lilly, and Regeneron about testing monoclonal antibodies as treatments for long COVID patients and was repeatedly declined.'

Peluso says his group at UCSF has taken this approach with Shionogi and Aerium, and more trials are on the way. But in the meantime, the specter of long COVID is only growing as more people around the world are infected with COVID-19.

"I don't want to paint this picture that is horrible," Peluso says. "But we just really need to get moving."
 
Jonathan Edwards said:
Then buy it in with your own bank account like I did and stop whingeing, mate.
But to be honest I cannot see any ethical justification for giving sick people something like that without some coherent theory.
It sounds very much like posturing to me.
Click to expand...
Would they sell it to the researchers at reduced cost and not the wholesale price? It says Keytruda is $11,500 a dose.
 
Washington Post: 'Women have a higher risk for long covid. Estrogen may play a role'

'A new study shows non-menopausal women between the ages of 40 and 54 had a significantly higher risk of developing long covid than men'

'Women have a higher risk of developing long covid than men, depending on their stage of life and whether they have experienced menopause, according to a new nationwide study from RECOVER, the long covid research initiative funded by the National Institutes of Health'

'Women with long covid also had increased levels of a gene that is associated with autoimmune disease, called Xist, compared with women who did not develop long covid, Blish said.'

'In contrast, Blish said, men with long covid appear to have a harder time killing off the coronavirus in the first place, which suggests that their symptoms may be a result of a more persistent infection.'
 
VT Digger: 'Mary Cushman: UVM Medical Center’s academic mission is critical to Vermonters’ health'

Mary Cushman is vice chair of medicine and co-director of the Vermont Center for Cardiovascular and Brain Health at the UVM Larner College of Medicine, and director of the thrombosis and hemostasis program at the UVM Medical Center.

'If UVMMC were to severely reduce or eliminate its research and educational activities, it would prevent stories like mine from being told.'

'Bridging from this research, we are now studying causes of long Covid, and we aim to develop knowledge that will bring treatments to the community of patients in Vermont suffering from the long-term debilitating effects of the virus.'
 
https://twitter.com/user/status/1892688215917613446


Science Translational Medicine: “Don't miss our webinar on #LongCovid, taking place tomorrow, 21 February at 1:30 p.m. ET.

Join @AndreaCoxMDPhD, @VirusesImmunity, and @MichaelPelusoMD as they discuss the latest discoveries, candidate drivers and heterogeneity, and emerging therapies: scim.ag/4jWzBQU”
 
Last edited:
New York Times: 'The Interview: Ed Yong Wants to Show You the Hidden Reality of the World'

'...his Covid journalism — which documented the earliest stages of the pandemic and made him one of the first chroniclers of long Covid...established Yong as a key and trusted public interpreter of the illness and its many ripples...'

'..I know that the cost of long Covid is real and substantial..'
 
Sharing for sight

“Notice to providers after Minnesota child develops rare brain inflammation linked to flu”

‘The Minnesota Department of Health recently issued a notice after a child under the age of two was diagnosed with a case of acute necrotizing encephalitis (ANE), associated with influenza A.“

-

CBS: “Health department warns Minnesota hospitals about rare flu-related brain inflammation”

Minnesota health officials are warning health care facilities after a Twin Cities child with the flu developed a case of rare brain inflammation.
 
Last edited:
You must log in or register to reply here.
Back
Top Bottom