Isolation of ultrasmall (filterable) bacteria from patients suffering from ME, and patients and staff of a paediatric hospital- Alharbi - Mar 2020

Discussion in 'ME/CFS research' started by Sly Saint, Mar 15, 2020.

  1. Sly Saint

    Sly Saint Senior Member (Voting Rights)

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    https://www.sciencedirect.com/science/article/pii/S1319562X20300887

    (is this the study that Karl Morten refers to?)
     
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  2. Andy

    Andy Committee Member

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  3. Dolphin

    Dolphin Senior Member (Voting Rights)

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  4. Hutan

    Hutan Moderator Staff Member

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    It seems that aqueous environments are a soup of ultra-small microorganisms...

    Another paper on the topic:
    Size Matters: Ultra-small and Filterable Microorganisms in the Environment 2020
    Abstract
    Ultra-small microorganisms are ubiquitous in Earth’s environments. Ultramicrobacteria, which are defined as having a cell volume of <0.1 μm3, are often numerically dominant in aqueous environments. Cultivated representatives among these bacteria, such as members of the marine SAR11 clade (e.g., “Candidatus Pelagibacter ubique”) and freshwater Actinobacteria and Betaproteobacteria, possess highly streamlined, small genomes and unique ecophysiological traits. Many ultramicrobacteria may pass through a 0.2-μm-pore-sized filter, which is commonly used for filter sterilization in various fields and processes. Cultivation efforts focusing on filterable small microorganisms revealed that filtered fractions contained not only ultramicrocells (i.e., miniaturized cells because of external factors) and ultramicrobacteria, but also slender filamentous bacteria sometimes with pleomorphic cells, including a special reference to members of Oligoflexia, the eighth class of the phylum Proteobacteria.

    ... Therefore, filtered fractions contain a greater variety and complexity of microorganisms than previously expected. This review summarizes the broad diversity of overlooked filterable agents remaining in “sterile” (<0.2-μm filtered) environmental samples.
     
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  5. Hutan

    Hutan Moderator Staff Member

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