Investigations of B cell phenotype and metabolic function in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Mensah, 2019 (PhD)

[Deleted member 3253]

Dated from April 2019, but I don't think this has been posted before.

I had thought most B-cell related work would've ended with the Rituximab trial failure, but apparently not:

https://discovery.ucl.ac.uk/id/eprint/10080812/20/Mensah_10080812_thesis_redacted.pdf

Just starting to work my way through, but very interesting indeed.

 

[Jonathan Edwards]

Dated from April 2019, but I don't think this has been posted before.

I had thought most B-cell related work would've ended with the Rituximab trial failure, but apparently not:

https://discovery.ucl.ac.uk/id/eprint/10080812/20/Mensah_10080812_thesis_redacted.pdf

Just starting to work my way through, but very interesting indeed.

The work was set up as a prelude to a potential further phase 2 trial in the UK about 5 years ago. It takes time for PhD projects to come to completion.

 

[Deleted member 3253]

The work was set up as a prelude to a potential further phase 2 trial in the UK about 5 years ago. It takes time for PhD projects to come to completion.

Yep, my fault. (I was brain-foggily thinking that the RTX trial was from a decade ago and so this must've been more novel - mixing the timeline up with XMRV).

 

[Trish]

Thread discussion of a paper published on his work by Fane Mensah here:
CD24 expression and B cell maturation shows a novel link with energy metabolism: potential implications for patients with ME/CFS, 2018, Mensah et al