Daridorexant - treatment for insomnia

I had tried this back in 2024 and couldn’t tolerate the side effects, also found it not helpful for sleep. Decided to give it another go. Went very slowly — halved the 25mg pill and took 12.5mg for 10 days. Increased to 25mg for 10 days. Then up to 37.5 (1.5 25mg pills). Each time I raised dose I’d have worse grogginess and brain fog during day. And sleep would work for one or two nights and then not. Stuck with it, now after a month, no daytime grogginess and — I turn out light and just fall asleep like a normal person. Sleep about 8 hours which is amazing. Don’t feel any better ME wise during day — was hoping the extra or deeper sleep might improve cognition — not so far.
 
Sounds like another of those cases where ME patients need to come in at a lower than standard dose and then increase more slowly than normal. I wonder how often this does actually happen with ME? Seems to be a lot.
 
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