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Covid-19 vaccines and vaccinations
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Snow Leopard
Senior Member (Voting Rights)
Hypothetically, but it depends on sufficient antigen dosage and B-cell/follicular dendritic cell response in germinal centres in the lymph. Perhaps viral vector vaccines will work better than live attenuated virus vaccines. But viral vector vaccines tend to rely on transfecting regular dendritic cells, which results in a strong T-cell response, but the antigen has to exit the cell and captured by follicular dendritic cells somehow (and in turn presented or preserved over time for later presentation to B-cells).
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Mij
Senior Member (Voting Rights)
Researchers have identified antibodies that may make coronavirus vaccines unnecessary.
A scientific breakthrough by Tel Aviv University: A team of researchers from the university has demonstrated that antibodies isolated from the immune system of recovered COVID-19 patients are effective in neutralizing all known strains of the virus, including the Delta and the Omicron variants. According to the researchers, this discovery may eliminate the need for repeated booster vaccinations and strengthen the immune system of populations at risk.
Researchers have identified antibodies that m | EurekAlert!
A scientific breakthrough by Tel Aviv University: A team of researchers from the university has demonstrated that antibodies isolated from the immune system of recovered COVID-19 patients are effective in neutralizing all known strains of the virus, including the Delta and the Omicron variants. According to the researchers, this discovery may eliminate the need for repeated booster vaccinations and strengthen the immune system of populations at risk.
Researchers have identified antibodies that m | EurekAlert!
Snow Leopard
Senior Member (Voting Rights)
Snow Leopard
Senior Member (Voting Rights)
I think the idea is that since they know the structure, they'll be manufactured as monoclonal antibodies.
Snow Leopard
Senior Member (Voting Rights)
That testing doesn't require long and complex clinical trials though. The testing is more akin to quality control.
The changes between vaccines are smaller than that of changes between annual Influenza vaccines - and as such they could be manufactured far quicker than currently, so long as health authorities actually commit to it.
perchance dreamer
Senior Member (Voting Rights)
I'm frustrated that the most prominent American politician said the pandemic is over on Sixty Minutes. He qualified that somewhat by saying there's still a lot more work to be done, but many people will focus only on his saying it's over. Congress was already resisting approving additional funds for more testing and vaccinations, so this gives certain members more cover for denying this much needed funding.
I think he was trying to offer encouragement after what we've all been through since 2020, but with around 420 Americans are dying daily from covid-related illnesses and so many getting long-term health problems from the virus, downplaying the severity of covid is the very last thing we should be doing. Anyway, it really shouldn't be a politician who announces the pandemic is over.
I think he was trying to offer encouragement after what we've all been through since 2020, but with around 420 Americans are dying daily from covid-related illnesses and so many getting long-term health problems from the virus, downplaying the severity of covid is the very last thing we should be doing. Anyway, it really shouldn't be a politician who announces the pandemic is over.
We have finally made it for my daughter's first vaccination.
She decided to go ahead last summer but health declined and GPs were no longer offering at home visits .
Health is not brilliant but a bit more stable and medical consultations now starting to come through, so she booked up herself ( a big thing in itself)
Sitting in post Jag waiting area ( having lowered average age by about 40 years) watching a queue of mainly pensioners without masks in an indoor foyer with not brilliant ventilation , and one healthcare worker almost using her mask as a chinstrap.
Over 2 years in ....
She decided to go ahead last summer but health declined and GPs were no longer offering at home visits .
Health is not brilliant but a bit more stable and medical consultations now starting to come through, so she booked up herself ( a big thing in itself)
Sitting in post Jag waiting area ( having lowered average age by about 40 years) watching a queue of mainly pensioners without masks in an indoor foyer with not brilliant ventilation , and one healthcare worker almost using her mask as a chinstrap.
Over 2 years in ....
Samuel
Senior Member (Voting Rights)
Merged thread
Moderna COVID-19 Booster Likely Triggers Acquired Angioedema
https://angioedemanews.com/news/covid-19-booster-vaccine-trigger-of-acquired-angioedema/
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p.s.
i have angioedema, with usual angioedema features, triggered by extremely small amounts of a specific, very common substance touching the skin anywhere. the touched location seems unrelated to where the angioedema reactions occur. the reactions are delayed.
c1-inh appears to be normal and the "take very large quantities of antihistamine for a very long time" test recommended in uptodate comes back as it's non-histaminergic [despite me having allergic/mcas features that seem urelated to the angioedema].
idk what subtype of angioedema this is or what the cause is, and the specific substance is not mentioned online or in uptodate as a trigger that i can find, all of the differential diagnoses are clearly very different and angioedema is the only match.
Moderna COVID-19 Booster Likely Triggers Acquired Angioedema
https://angioedemanews.com/news/covid-19-booster-vaccine-trigger-of-acquired-angioedema/
===
p.s.
i have angioedema, with usual angioedema features, triggered by extremely small amounts of a specific, very common substance touching the skin anywhere. the touched location seems unrelated to where the angioedema reactions occur. the reactions are delayed.
c1-inh appears to be normal and the "take very large quantities of antihistamine for a very long time" test recommended in uptodate comes back as it's non-histaminergic [despite me having allergic/mcas features that seem urelated to the angioedema].
idk what subtype of angioedema this is or what the cause is, and the specific substance is not mentioned online or in uptodate as a trigger that i can find, all of the differential diagnoses are clearly very different and angioedema is the only match.
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The reaction occurred 72 hours after the vaccination. It's hard to know in this case if the swelling around the throat would have happened without the vaccination, given the past episodes of upper limb swelling. More likely, perhaps it would have been triggered by any immunological challenge - in this case it was a vaccination but if the man had not had the vaccination, perhaps it would have happened when he next got a cold or something.
Moved post
Ofcom investigation into GB News’ Mark Steyn programme
"Ofcom has today opened an investigation into an episode of the Mark Steyn programme broadcast on GB News on 4 October 2022.
We consider that comments made during an interview with author and journalist Dr Naomi Wolf about the coronavirus vaccine rollout raise potential issues under our Broadcasting Code.
Specifically, our investigation will consider whether this programme broke our rules designed to protect viewers from harmful material.
We received 411 viewer complaints (PDF, 108.2 KB) about Dr Wolf’s comments."
Ofcom investigation into GB News’ Mark Steyn programme
"Ofcom has today opened an investigation into an episode of the Mark Steyn programme broadcast on GB News on 4 October 2022.
We consider that comments made during an interview with author and journalist Dr Naomi Wolf about the coronavirus vaccine rollout raise potential issues under our Broadcasting Code.
Specifically, our investigation will consider whether this programme broke our rules designed to protect viewers from harmful material.
We received 411 viewer complaints (PDF, 108.2 KB) about Dr Wolf’s comments."
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Binkie4
Senior Member (Voting Rights)
Some facebook groups have been sharing information about the following testimony before the European Parliament.
Viral transmission not tested in Pfizer trials.
"Pfizer did not know whether Covid vaccine stopped transmission before rollout https://www.news.com.au/technology/sc... https://www.youtube.com/watch?v=mnxlx... https://www.news.com.au/technology/sc... Janine Small Pfizer’s president of international developed markets Testifying before the European Union Parliament, Monday 10th October Dutch MEP Rob Roos ‘Was the Pfizer Covid vaccine tested on stopping the transmission of the virus before it entered the market?
If not, please say it clearly.
If yes, are you willing to share the data with this committee? And I really want a straight answer, yes or no, and I’m looking forward to it.”
Ms Small “Regarding the question around, um, did we know about stopping the immunisation before it entered the market? No Therefore Pfizer Covid vaccine was not tested on stopping the transmission of the virus before it entered the market Ms Small you know, we had to really move at the speed of science to really understand what is taking place in the market, and from that point of view we had to do everything at risk. I think Dr Bourla, even though he’s not here, would turn around and say to you himself, ‘If not us then who?’” Ms Small said Dr Bourla “actually felt the importance of what was going on in the world, and therefore as a result of that, we actually, um, spent $US2 billion, at risk, of self-funded money from Pfizer, to be able to research, develop and manufacture at risk, to be able to make sure that we were in a position to be able to help with the pandemic”. Mr Roos scandalous “Millions of people worldwide felt forced to get vaccinated because of the myth that ‘you do it for others’ “Now this turned out to be a cheap lie. This should be exposed.”
Apologies for the close script.
It's not easy to see who is saying what except that Pfizer did not know whether its vaccine stopped transmission before rollout.
From memory this is not what was said in Govt messaging. Many care workers who refused the vaccine lost their jobs.
John Campbell has reported on it this evening calling it " a breaking international scandal."
Viral transmission not tested in Pfizer trials.
"Pfizer did not know whether Covid vaccine stopped transmission before rollout https://www.news.com.au/technology/sc... https://www.youtube.com/watch?v=mnxlx... https://www.news.com.au/technology/sc... Janine Small Pfizer’s president of international developed markets Testifying before the European Union Parliament, Monday 10th October Dutch MEP Rob Roos ‘Was the Pfizer Covid vaccine tested on stopping the transmission of the virus before it entered the market?
If not, please say it clearly.
If yes, are you willing to share the data with this committee? And I really want a straight answer, yes or no, and I’m looking forward to it.”
Ms Small “Regarding the question around, um, did we know about stopping the immunisation before it entered the market? No Therefore Pfizer Covid vaccine was not tested on stopping the transmission of the virus before it entered the market Ms Small you know, we had to really move at the speed of science to really understand what is taking place in the market, and from that point of view we had to do everything at risk. I think Dr Bourla, even though he’s not here, would turn around and say to you himself, ‘If not us then who?’” Ms Small said Dr Bourla “actually felt the importance of what was going on in the world, and therefore as a result of that, we actually, um, spent $US2 billion, at risk, of self-funded money from Pfizer, to be able to research, develop and manufacture at risk, to be able to make sure that we were in a position to be able to help with the pandemic”. Mr Roos scandalous “Millions of people worldwide felt forced to get vaccinated because of the myth that ‘you do it for others’ “Now this turned out to be a cheap lie. This should be exposed.”
Apologies for the close script.
It's not easy to see who is saying what except that Pfizer did not know whether its vaccine stopped transmission before rollout.
From memory this is not what was said in Govt messaging. Many care workers who refused the vaccine lost their jobs.
John Campbell has reported on it this evening calling it " a breaking international scandal."