1. Guest, the 'News in Brief' for the week beginning 15th February 2021 is here.
    Dismiss Notice
  2. Welcome! To read the Core Purpose and Values of our forum, click here.
    Dismiss Notice

Circadian rhythm abnormalities and autonomic dysfunction in patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis, 2018, Cambras et al

Discussion in 'BioMedical ME/CFS Research' started by Andy, Jun 8, 2018.

  1. Andy

    Andy Committee Member & Outreach

    Messages:
    12,028
    Likes Received:
    86,484
    Location:
    Hampshire, UK
    Open access at http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198106
     
  2. Hutan

    Hutan Moderator Staff Member

    Messages:
    12,253
    Likes Received:
    50,562
    Location:
    New Zealand
    These seem like well-meaning researchers.

    Can someone invite them to a conference so that they can update their knowledge on GET? And/or send them some information about the PACE trial?
     
  3. Andy

    Andy Committee Member & Outreach

    Messages:
    12,028
    Likes Received:
    86,484
    Location:
    Hampshire, UK
    Actually their evidence for their statement isn't the PACE trial. Their reference is "Patient education to encourage graded exercise in chronic fatigue syndrome. 2-year follow-up of randomised controlled trial.", https://www.ncbi.nlm.nih.gov/pubmed/14754826, this response to the study, https://www.bmj.com/content/322/7301/1545, seems to indicate many of the usual problems with it.
     
  4. Trish

    Trish Moderator Staff Member

    Messages:
    30,512
    Likes Received:
    145,408
    Location:
    UK
    Strange to use as evidence an obscure trial from 15 or more years ago.
     
  5. adambeyoncelowe

    adambeyoncelowe Senior Member (Voting Rights)

    Messages:
    2,285
    Likes Received:
    16,515
    Maybe they know PACE will no longer fly?
     
  6. Hutan

    Hutan Moderator Staff Member

    Messages:
    12,253
    Likes Received:
    50,562
    Location:
    New Zealand
    I suggested sending information about the PACE trial simply because it is a large trial that proves that GET doesn't 'markedly improve symptoms and activities of daily living' in people with ME/CFS.
     
  7. Trish

    Trish Moderator Staff Member

    Messages:
    30,512
    Likes Received:
    145,408
    Location:
    UK
    A discussion of thyroid issues on this thread has been moved to a more relevant thread here at the poster's request.
     
    Hutan and Inara like this.
  8. Little Bluestem

    Little Bluestem Senior Member (Voting Rights)

    Messages:
    1,450
    Likes Received:
    8,871
    Well most of this is over my head, so I calculated the above. That is over 10 thousand (10,920) data points per person! :)
     
    Inara and Indigophoton like this.

Share This Page