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metabolism

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  1. Sly Saint
    Thread

    A SWATH-MS analysis of ME/CFS peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction: Sweetman,Vallings,Tate et al Aug 2020

    A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial...
    Thread by: Sly Saint, Aug 20, 2020, 17 replies, in forum: BioMedical ME/CFS Research
  2. Sly Saint
    Thread

    Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations - [new article 2020]

    Basal glycolysis is reduced in ME/CFS CD4+ T cells. https://www.jci.org/articles/view/132185/figure/4 paper from December 2019...
    Thread by: Sly Saint, Feb 11, 2020, 5 replies, in forum: BioMedical ME/CFS Research
  3. Sly Saint
    Thread

    Comprehensive Circulatory Metabolomics in ME/CFS Reveals Disrupted Metabolism of Acyl Lipids and Steroids: Levine,Hanson et al 2020

    Article. PDF Received: 20 December 2019; Accepted: 12 January 2020; Published: 14 January 2020 Abstract: The latest worldwide prevalence rate...
    Thread by: Sly Saint, Jan 14, 2020, 40 replies, in forum: BioMedical ME/CFS Research
  4. Trish
    Thread

    Is ME a metabolic problem or a signalling problem?

    I am trying to get my head around the question of whether ME could be a metabolic problem, as suggested by the 'something in the blood' findings...
    Thread by: Trish, Aug 27, 2019, 131 replies, in forum: BioMedical ME/CFS News
  5. Sly Saint
    Thread

    Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health - Parker,Fonseca,Carding Aug 2019

    ABSTRACT The human gastrointestinal (gut) microbiota comprises diverse and dynamic populations of bacteria, archaea, viruses, fungi, and protozoa,...
    Thread by: Sly Saint, Aug 3, 2019, 11 replies, in forum: Health News and Research unrelated to ME/CFS
  6. Sly Saint
    Thread

    Importance of fatigue and its measurement in chronic liver disease - Gerber et al Jul 28 2019

    Opinion Piece Abstract The mechanisms of fatigue in the group of people with non-alcoholic fatty liver disease and non-alcoholic steatohepatitis...
    Thread by: Sly Saint, Jul 29, 2019, 2 replies, in forum: Health News and Research unrelated to ME/CFS
  7. hixxy
    Thread

    Incomplete Healing as a Cause of Aging: The Role of Mitochondria and the Cell Danger Response (2019) Naviaux

    Biology (Basel). 2019 May 11;8(2). pii: E27. doi: 10.3390/biology8020027. Incomplete Healing as a Cause of Aging: The Role of Mitochondria and...
    Thread by: hixxy, May 15, 2019, 13 replies, in forum: BioMedical ME/CFS Research
  8. Andy
    Thread

    Gut bacteria signaling to mitochondria in intestinal inflammation and cancer, 2019, Jackson and Theiss

    ABSTRACT The gastrointestinal microbiome plays a pivotal role in physiological homeostasis of the intestine as well as in the pathophysiology of...
    Thread by: Andy, Apr 7, 2019, 0 replies, in forum: Health News and Research unrelated to ME/CFS
  9. kmclellan
    Thread

    Reduced Metabolism in Nematodes linked to the Immune System

    Perhaps not that interesting of a read but it is a very interesting discovery for people with ME. You may recall the metabolomics study of 2017...
    Thread by: kmclellan, Mar 24, 2019, 2 replies, in forum: Health News and Research unrelated to ME/CFS
  10. Andy
    Thread

    Comparison of differential metabolites in urine of the middle school students with CFS before and after exercise, 2018, Chi et al

    Abstract OBJECTIVE: To study the differential metabolites in urine and the characteristics of metabolic pathway of middle school students with...
    Thread by: Andy, Feb 25, 2019, 2 replies, in forum: BioMedical ME/CFS Research
  11. Andy
    Thread

    Review: A role for corticosteroid-binding globulin variants in stress-related disorders, 2014, Marathe & Torpey

    Not sure why this has come up as recently published but thought I'd still post it. I think this should be in biomed research but obviously it can...
    Thread by: Andy, Feb 23, 2019, 1 replies, in forum: BioMedical ME/CFS Research
  12. Andy
    Thread

    Mitochondrial complex III is essential for suppressive function of regulatory T cells, 2019, Chandel et al

    Abstract Regulatory T cells (Treg cells), a distinct subset of CD4+ T cells, are necessary for the maintenance of immune self-tolerance and...
    Thread by: Andy, Jan 15, 2019, 1 replies, in forum: Health News and Research unrelated to ME/CFS
  13. leokitten
    Thread

    Since ME breathing rate significantly slower than normal/used to. Further evidence of metabolic dysfunction?

    One ME symptom I’ve had since I fell ill is my breathing rate is significantly slower than normal and than I used to breathe before falling ill....
    Thread by: leokitten, Jan 15, 2019, 19 replies, in forum: Cardiovascular and Respiratory
  14. Cheshire
    Thread

    Evidence of widespread metabolite abnormalities in ME/CFS: assessment with whole-brain magnetic resonance spectroscopy (2019) Younger et al.

    Christina Mueller, Joanne C. Lin, Sulaiman Sheriff, Andrew A. Maudsley, Jarred W. Younger Previous neuroimaging studies have detected markers of...
    Thread by: Cheshire, Jan 9, 2019, 22 replies, in forum: BioMedical ME/CFS Research
  15. Andy
    Thread

    Chronic fatigue syndrome and mitochondrial dysfunction, 2009, Myhill et al

    An old study but, as shown in this thread, https://s4me.info/threads/top-10-sc...f-citations-tweet-by-dr-mark-gutheridge.7461/, one of the most...
    Thread by: Andy, Jan 2, 2019, 1 replies, in forum: BioMedical ME/CFS Research
  16. Dolphin
    Thread

    Lefever (2018) "Hypophosphatasia in adults: clinical spectrum and its association with genetics and metabolic substrates" (differential diagnosis)

    https://www.sciencedirect.com/science/article/pii/S1094695018302440 Journal of Clinical Densitometry Available online 21 December 2018 In Press,...
    Thread by: Dolphin, Dec 25, 2018, 0 replies, in forum: BioMedical ME/CFS Research
  17. John Mac
    Thread

    Prospective Biomarkers from Plasma Metabolomics of ME/CFS Implicate Redox Imbalance in Disease Symptomatology, 2018, Hanson et al

    Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disease of enigmatic origin with no established cure. Its constellation of...
    Thread by: John Mac, Dec 6, 2018, 15 replies, in forum: BioMedical ME/CFS Research
  18. Andy
    Thread

    Metabolism reprogrammed by the nitric oxide signalling molecule

    Acute kidney injury can lead to chronic renal failure, which causes fluid and electrolyte imbalances in the blood that require dialysis. Such...
    Thread by: Andy, Dec 5, 2018, 9 replies, in forum: Health News and Research unrelated to ME/CFS
  19. Sly Saint
    Thread

    The expression signature of very long non-coding RNA in myalgic encephalomyelitis/chronic fatigue syndrome, 2018, Chin-An Yang et al

    The expression signature of very long non-coding RNA in myalgic encephalomyelitis/chronic fatigue syndrome Chin-An YangView ORCID ID profile,...
    Thread by: Sly Saint, Aug 18, 2018, 15 replies, in forum: BioMedical ME/CFS Research
  20. hixxy
    Thread

    Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-Metabolic Disease or Disturbed Homeostasis? (2018) Theoharides et al

    J Pharmacol Exp Ther. 2018 Aug 3. pii: jpet.118.250845. doi: 10.1124/jpet.118.250845. [Epub ahead of print] Myalgic Encephalomyelitis/Chronic...
    Thread by: hixxy, Aug 6, 2018, 5 replies, in forum: BioMedical ME/CFS Research
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