metabolism

  1. SNT Gatchaman

    Hypothesis The Case for the Target of Rapamycin Pathway as a Candidate Circadian Oscillator, 2023, Lakin-Thomas

    The Case for the Target of Rapamycin Pathway as a Candidate Circadian Oscillator Lakin-Thomas, Patricia The molecular mechanisms that drive circadian (24 h) rhythmicity have been investigated for many decades, but we still do not have a complete picture of eukaryotic circadian systems. Although...
  2. SNT Gatchaman

    Review Studying the Human Microbiota: Advances in Understanding the Fundamentals, Origin, and Evolution of Biological Timekeeping, 2023, Siebieszuk et al.

    Studying the Human Microbiota: Advances in Understanding the Fundamentals, Origin, and Evolution of Biological Timekeeping Siebieszuk, Adam; Sejbuk, Monika; Witkowska, Anna Maria The recently observed circadian oscillations of the intestinal microbiota underscore the profound nature of the...
  3. SNT Gatchaman

    Preprint Regional quantification of cardiac metabolism with hyperpolarized 1-13C-pyruvate MRI evaluated in an oral glucose challenge, 2023, Larson et al.

    Regional quantification of cardiac metabolism with hyperpolarized 1-13C-pyruvate MRI evaluated in an oral glucose challenge Peder E. Z. Larson; Shuyu Tang; Xiaoxi Liu; Avantika Sinha; Nicholas Dwork; Sanjay Sivalokanathan; Jing Liu; Robert Bok; Karen G Ordovas; James Slater; Jeremy Gordon; Maria...
  4. E

    Brain fog in long COVID: A glutamatergic hypothesis with astrocyte dysfunction accounting for brain PET glucose hypometabolism, 2023, Guedj et al

    Brain fog in long COVID: A glutamatergic hypothesis with astrocyte dysfunction accounting for brain PET glucose hypometabolism Abstract Brain [18F]FDG-PET scans have revealed a glucose hypometabolic pattern in patients with long COVID. This hypometabolism might reflect primary astrocyte...
    • EndME
    • Thread
    • astrocytes glial cells glucose glutamate long covid metabolism pet scan
    • Replies: 1
    • Forum: Long Covid research
  5. SNT Gatchaman

    Review Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19, 2023, Nair et al.

    Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19 Nair, Soumyalekshmi; Nova-Lamperti, Estefania; Labarca, Gonzalo; Kulasinghe, Arutha; Short, Kirsty R.; Carrión, Flavio; Salomon, Carlos COVID-19 continues to affect an unprecedented number...
    • SNT Gatchaman
    • Thread
    • epigenetics extracellular vesicles gene expression glucose innate immune system lipid metabolism long covid metabolism sars-cov-2 spike protein thrombosis
    • Replies: 0
    • Forum: Long Covid research
  6. SNT Gatchaman

    Plasma proteomics show altered inflammatory and mitochondrial proteins in patients with ... post-acute sequelae of SARS-CoV-2, 2023, B. Hanson et al

    Plasma proteomics show altered inflammatory and mitochondrial proteins in patients with neurologic symptoms of post-acute sequelae of SARS-CoV-2 infection Hanson; Visvabharathy; Orban; Jimenez; Batra; Liotta; DeLisle; Klausner; Cohen; Padhye; Tachas; Koralnik Persistent symptoms of COVID-19...
    • SNT Gatchaman
    • Thread
    • biomarker brain fog cox7a1 long covid metabolism mitochondria oxphos proteome proteomics
    • Replies: 7
    • Forum: Long Covid research
  7. SNT Gatchaman

    Structural and functional impairments of skeletal muscle in patients with [PASC], 2023, Colosio et al.

    Structural and functional impairments of skeletal muscle in patients with post-acute sequelae of SARS-CoV-2 infection Marta Colosio ; Lorenza Brocca ; Marco Gatti ; Marianna Neri ; Emanuela Crea ; Francesca Cadile ; Monica Canepari ; Maria Antonietta Pellegrino ; Biagio Polla ; Simone...
    • SNT Gatchaman
    • Thread
    • cpet drp1 italy long covid metabolism mitochondria muscle biopsy oxygen extraction study idea
    • Replies: 10
    • Forum: Long Covid research
  8. SNT Gatchaman

    Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts, 2023, Guarnieri et al.

    Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts Joseph W. Guarnieri; Joseph M. Dybas; Hossein Fazelinia; Man S. Kim; Justin Frere; Yuanchao Zhang; Yentli Soto Albrecht; Deborah G. Murdock; Alessia Angelin; Larry N. Singh; Scott L. Weiss; Sonja M...
    • SNT Gatchaman
    • Thread
    • covid fgf21 gdf15 glycolysis glyolysis hif-1 integrated stress response long covid mavs metabolism micro-rna mitochondria oxphos slc25
    • Replies: 14
    • Forum: Long Covid research
  9. SNT Gatchaman

    A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy, 2023, Southwell et al.

    A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy Nneka Southwell; Guido Primiano; Viraj Nadkarni; Nabeel Attarwala; Emelie Beattie; Dawson Miller; Sumaitaah Alam; Irene Liparulo; Yevgeniya I Shurubor; Maria Lucia Valentino; Valerio Carelli; Serenella...
    • SNT Gatchaman
    • Thread
    • amino acids atf4 fatty acid metabolism fatty acid oxidation fgf21 gdf15 integrated stress response lipid droplets lipid metabolism lipids metabolism mitochondria mtor muscle myopathy tca cycle
    • Replies: 4
    • Forum: Other health news and research
  10. SNT Gatchaman

    Mitochondria and oxygen homeostasis, 2022, Mori, Hwang et al.

    Mitochondria and oxygen homeostasis Mateus P. Mori; Rozhin Penjweini; Jay R. Knutson; Ping-yuan Wang; Paul M. Hwang Molecular oxygen possesses a dual nature due to its highly reactive free radical property: it is capable of oxidizing metabolic substrates to generate cellular energy, but can...
  11. SNT Gatchaman

    SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution, 2020, Argüello et al.

    SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution Rafael J. Argüello; Alexis J. Combes; Remy Char; Julien-Paul Gigan; Ania I. Baaziz; Evens Bousiquot; Voahirana Camosseto; Bushra Samad; Jessica Tsui; Peter Yan; Sebastien Boissonneau...
  12. SNT Gatchaman

    Suppressed immune and metabolic responses to intestinal damage-associated microbial translocation in [ME/CFS], 2023, Uhde, Vernon et al.

    Suppressed immune and metabolic responses to intestinal damage-associated microbial translocation in myalgic encephalomyelitis/chronic fatigue syndrome Uhde; Indart; Green; Yolken; Cook; Shukla; Vernon; Alaedini The etiology and mechanism of myalgic encephalomyelitis/chronic fatigue syndrome...
    • SNT Gatchaman
    • Thread
    • gut gut microbiome il-10 immune system innate immune response metabolism microbiome
    • Replies: 15
    • Forum: ME/CFS research
  13. SNT Gatchaman

    Extensive Brain Pathologic Alterations Detected with 7.0-T MR Spectroscopic Imaging Associated with Disability in Multiple Sclerosis, 2022, Heckova+

    Extensive Brain Pathologic Alterations Detected with 7.0-T MR Spectroscopic Imaging Associated with Disability in Multiple Sclerosis Eva Heckova; Assunta Dal-Bianco; Bernhard Strasser; Gilbert J. Hangel; Alexandra Lipka; Stanislav Motyka; Lukas Hingerl; Paulus S. Rommer; Thomas Berger; Petra...
  14. SNT Gatchaman

    Neurovascular Coupling

    Neurovascular coupling is the concept that in the CNS, organ function is tightly associated with blood flow, moreso than in other organs. Theoretical background and latest thinking — From the introduction in The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in...
  15. SNT Gatchaman

    Preprint Thermosensitivity of translation underlies the mammalian nocturnal-diurnal switch, 2023, Beale et al.

    Thermosensitivity of translation underlies the mammalian nocturnal-diurnal switch Andrew David Beale; Nina M Rzechorzek; Andrei Mihut; Aiwei Zeng; Nicola J Smyllie; Violetta Pilorz; Rose Richardson; Mads F Bertlesen; Nathan R James; Shaline V Fazal; Zanna Voysey; Jerry Pelletier; Priya Crosby...
  16. SNT Gatchaman

    Associations of circulating metabolites with cerebral white matter hyperintensities, 2023, Sun et al.

    Associations of circulating metabolites with cerebral white matter hyperintensities Yan Sun; Yu Guo; Hong-Qi Li; Lan Tan; Jian-Feng Feng; Wei Cheng; Jin-Tai Yu White matter hyperintensities (WMH) are the most compelling risk factors of stroke, dementia, and early mortality. We aimed to...
  17. SNT Gatchaman

    Preprint Loss of Skeletal Muscle Pyruvate Dehydrogenase Induces Lactic Acidosis & Adaptive Anaplerotic Compensation, 2023, Gopal et al.

    Loss of Skeletal Muscle Pyruvate Dehydrogenase Induces Lactic Acidosis and Adaptive Anaplerotic Compensation via Pyruvate-Alanine Cycling and Glutaminolysis Keshav Gopal; Abdualrahman Mohammed Abdualkader; Xiaobei Li; Amanda A. Greenwell; Qutuba G. Karwi; Christina Saed; Golam M. Uddin; Ahmed M...
  18. Andy

    Metabolic features of chronic fatigue syndrome 2016 Naviaux et al

    Significance Chronic fatigue syndrome is a multisystem disease that causes long-term pain and disability. It is difficult to diagnose because of its protean symptoms and the lack of a diagnostic laboratory test. We report that targeted, broad-spectrum metabolomics of plasma not only revealed a...
    • Andy
    • Thread
    • amino acids lipids metabolism mitochondria sphingolipids
    • Replies: 1
    • Forum: ME/CFS research
  19. SNT Gatchaman

    Transforming Growth Factor-β: An Agent of Change in the Tumor Microenvironment, 2021, Stuelten et al.

    Transforming Growth Factor-β: An Agent of Change in the Tumor Microenvironment Stuelten, Christina H.; Zhang, Ying E. Transforming Growth Factor-β (TGF-β) is a key regulator of embryonic development, adult tissue homeostasis, and lesion repair. In tumors, TGF-β is a potent inhibitor of early...
    • SNT Gatchaman
    • Thread
    • aerobic glycolysis cancer immune dysfunction immune function metabolic reprogramming metabolism mitochondria oxidative phosphorylation tgf-beta tgf-β transforming growth factor tsp-1 tsp1
    • Replies: 7
    • Forum: Other health news and research
  20. SNT Gatchaman

    Nuclear Magnetic Resonance Spectroscopy Metabolomics in Idiopathic Intracranial Hypertension to Identify Markers of Disease and Headache, 2022, Grech

    Nuclear Magnetic Resonance Spectroscopy Metabolomics in Idiopathic Intracranial Hypertension to Identify Markers of Disease and Headache Grech O, Seneviratne SY, Alimajstorovic Z, Yiangou A, Mitchell JL, Smith TB, Mollan SP, Lavery GG, Ludwig C, Sinclair AJ Background and objective: We...
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