sex differences

Sex differences and immune correlates of Long COVID development, persistence, and resolution Rebecca E Hamlin; Shaun M Pienkos; Leslie Chan; Mikayla A Stabile; Kassandra Pinedo; Mallika Rao; Philip Grant; Hector Bonilla; Marisa Holubar; Upinder Singh; Karen B Jacobson; Prasanna Jagannathan...

Preprint, see post #39 for peer-reviewed version ------------------------------------------------------------- Oxidative Stress is a shared characteristic of ME/CFS and Long COVID Vishnu Shankar; Julie Wilhelmy; Basil Michael; Layla Cervantes; Vamsee Mallajosyula; Ronald Davis; Michael Snyder...

Towards understanding post-COVID-19 condition: A systematic meta-analysis of transcriptomic alterations with sex-specific insights Rusu; Monfort-Lanzas; Bertran; Barrientos-Riosalido; Solé; Mahmoudian; Aguilar; Briansó; Mohamed; Garcia; Camaron; Auguet BACKGROUND Post COVID-19 Condition (PCC)...

Abstract Males and females experience different trajectories of neuromuscular function across the lifespan, with females demonstrating accelerated deconditioning in later life. We hypothesize that the menopause is a critical period in the female lifespan, during which the dramatic reduction in...

Transcription Profile Analysis of Vastus Lateralis Muscle from Patients with Chronic Fatigue Syndrome T. Pietrangelo; R. Mancinelli; L. Toniolo; G. Montanari; J. Vecchiet; G. Fanò; S. Fulle Chronic fatigue syndrome (CFS) is a disabling condition characterized by unexplained chronic fatigue that...

The Effect of Sex on the Risk of Long-COVID and Cardiovascular Complications in Healthy Patients without Comorbidities: Data from a Polish Long-COVID Cardiovascular PoLoCOV-CVD Study Bielecka-Dabrowa, Agata; Sakowicz, Agata; Gryglewska-Wawrzak, Katarzyna; Kapusta, Joanna; Banach, Maciej...

Post-COVID-19 condition: systemic inflammation and low functional exercise capacity de Castro, Gabriela Salim; Gama, Leonardo R.; Ramos, Alexandre Ferreira; Gatti da Silva, Guilherme; Teixeira, Alexandre Abilio de Souza; Cunha-Neto, Edecio; de Souza, Heraldo Possolo; Marie, Suely K.; Talib, Leda...

Prevalence of autoimmune diseases in functional neurological disorder: influence of psychiatric comorbidities and biological sex Anna Joseph; Gaston Baslet; Mary A O’Neal; Ginger Polich; Irene Gonsalvez; Andrea N Christoforou; Barbara A Dworetzky; Primavera A Spagnolo BACKGROUND Functional...

Abstract The genetic and genomic basis of sex differences in blood pressure (BP) traits remain unstudied at scale. Here, we conducted sex-stratified and combined-sex genome-wide association studies of BP traits using the UK Biobank resource, identifying 1,346 previously reported and 29 new BP...

Accelerated brain age in young to early middle-aged adults after mild to moderate COVID-19 infection Shelli R Kesler; Oscar Y Franco-Rocha; Alexa De La Torre Schutz; Kimberly A. Lewis; Rija Aziz; Michael Brode; Esther Melamed Cognitive decline is a common adverse effect of the Coronavirus...

Sex differences in post-acute neurological sequelae of SARS-CoV-2 and symptom resolution in adults after coronavirus disease 2019 hospitalization: an international multi-centre prospective observational study 605 authors not listed Although it is known that coronavirus disease 2019 can present...

Sex differences in symptomatology and immune profiles of Long COVID Julio Silva; Takehiro Takahashi; Jamie Wood; Peiwen Lu; Sasha Tabachnikova; Jeffrey Gehlhausen; Kerrie Greene; Bornali Bhattacharjee; Valter Silva Monteiro; Carolina Lucas; Rahul Dhodapkar; Laura Tabacof; Mario Pena-Hernandez...

[In mice] Introduction: Post-infection syndromes are characterised by fatigue, muscle pain, anhedonia, and cognitive impairment; mechanistic studies exploring these syndromes have focussed on pathways downstream of Toll-like receptor (TLR) 4 activation. Here, we investigated the mechanistic...

Impact of sex and gender on post-COVID-19 syndrome, Switzerland, 2020 Caroline E Gebhard; Claudia Sütsch; Pimrapat Gebert; Bianca Gysi; Susan Bengs; Atanas Todorov; Manja Deforth; Philipp K Buehler; Alexander Meisel; Reto A Schuepbach; Annelies S Zinkernagel; Silvio D Brugger; Claudio Acevedo...

Sex-dependent differences in type I IFN-induced natural killer cell activation Pujantell, Maria; Skenteris, Nikolaos-Taxiarchis; Claussen, Janna Marieke; Grünhagel, Benjamin; Thiele, Rebecca-Jo; Altfeld, Marcus Natural killer (NK) cells are important antiviral effector cells and also involved...

SARS-CoV-2 spike antigen-specific B cell and antibody responses in pre-vaccination period COVID-19 convalescent males and females with or without post-covid condition Limoges, Marc-André; Quenum, Akouavi Julite Irmine; Chowdhury, Mohammad Mobarak Hussain; Rexhepi, Fjolla; Namvarpour, Mozhdeh...

Severe, Persistent, Disruptive Fatigue Post-SARS-CoV-2 Disproportionately Affects Young Women Jillian Kallman Price; Leyla de Avila; Maria Stepanova; Ali A Weinstein; Huong Pham; Wisna’odom Keo; Andrei Racila; Suzannah Gerber; Brian P Lam; Lynn H Gerber; Zobair M Younossi Introduction...

Full title: Sex-Dependent Transcriptional Changes in Response to Stress in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Project Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, multi-symptom illness characterized by debilitating...

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population Gaya da Costa, Mariana; Poppelaars, Felix; van Kooten, Cees; Mollnes, Tom E.; Tedesco, Francesco; Würzner, Reinhard; Trouw, Leendert A.; Truedsson, Lennart; Daha, Mohamed R.; Roos, Anja...

The Pathological Activation of Microglia Is Modulated by Sexually Dimorphic Pathways O'Connor, Jennifer L.; Nissen, Jillian C. Microglia are the primary immunocompetent cells of the central nervous system (CNS). Their ability to survey, assess and respond to perturbations in their local...