scheibenbogen

Panelists — Michael Edelstein Akiko Iwasaki Marc Lecuit Carmen Scheibenbogen

Repeat Immunoadsorption Post Covid ME/CFS https://clinicaltrials.gov/ct2/show/NCT05629988 From Dr. Carmen Scheibenbogen's team at Charite University. Their summary: It's an observational study with no control group, so not rigorous. But after this study they want to do an RCT.

Abstract Background Muscle fatigue and pain are key symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Although the pathophysiology is not yet fully understood, there is ample evidence for hypoperfusion which may result in electrolyte imbalance and sodium overload in...

Most patients with Post COVID Syndrome (PCS) present with a plethora of symptoms without clear evidence of organ dysfunction. A subset of them fulfills diagnostic criteria of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Symptom severity of ME/CFS correlates with natural...

Moved from the News from Germany thread. From the twitter thread above: About vericiguat, which does sound interesting:

October 24 @ 10:00 am - 11:00 am PDT Organizer Solve M.E. https://solvecfs.org/event/covid-19-as-a-trigger-for-me-cfs-severity-biomarkers-and-underlying-mechanisms/

Abstract Background A sizable part of post-COVID syndrome meets the diagnostic criteria for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). A doubling of cases of ME/CFS within the next years is therefore projected. Objectives Presentation of the current state of knowledge on...

Editorial: Current Insights Into Complex Post-infection Fatigue Syndromes With Unknown Aetiology: The Case of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Westermeier, Lacerda, Scheibenbogen, Sepulveda Conclusions In conclusion, this Research Topic collects further pieces of evidence...

Myalgic encephalomyelitis (ME) or Chronic Fatigue Syndrome (CFS) is a neglected, debilitating multi-systemic disease without diagnostic marker or therapy. Despite evidence for neurological, immunological, infectious, muscular and endocrine pathophysiological abnormalities, the etiology and a...

An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome Klaus J. Wirth, Carmen Scheibenbogen and Friedemann Paul Abstract There is accumulating evidence of endothelial dysfunction, muscle and cerebral hypoperfusion in Myalgic...

Thread split from The micro-clot finding in Long Covid — implications for the possible aetiology of ME/CFS ***************** https://www.nature.com/articles/s41380-021-01148-4 Chronic post-COVID-19 syndrome and chronic fatigue syndrome: Is there a role for extracorporeal apheresis? 2021

https://www.sciencedirect.com/science/article/abs/pii/S0198885915004656 S. Guenther, M. Loebel, A. Mooslechner, M. Knops, L. Hanitsch, P. Grabowski, K. Wittke, C. Meisel, N. Unterwalder, H. Volka, Carmen Scheibenbogen Abstract Chronic fatigue syndrome (CFS) is a severe disease characterized by...

This thread was split from Open Medicine Foundation (OMF) News I thought we could not conclude autoimmunity is likely out of the picture as long as we dont know how to target long lived plasma cells? I mean b-cells dont really matter at that point if im not mistanken, as the autoimmune plasma...

Autoantibodies to Vasoregulative G-Protein-Coupled Receptors Correlate with Symptom Severity, Autonomic Dysfunction and Disability in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Scheibenbogen et al Abstract Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is an...

Abstract Background and Objective: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a severe illness with the hallmark symptom of Post-Exertional Malaise (PEM). Currently, no biomarkers or established diagnostic tests for ME/CFS exist. In Germany, it is estimated that over 300,000...

Abstract Chronic Fatigue Syndrome or Myalgic Encephaloymelitis (ME/CFS) is a frequent debilitating disease with an enigmatic etiology. The finding of autoantibodies against ß2-adrenergic receptors (ß2AdR) prompted us to hypothesize that ß2AdR dysfunction is of critical importance in the...

Abstract Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex and debilitating disease accompanied by muscular fatigue and pain. A functional measure to assess muscle fatigability of ME/CFS patients is, however, not established in clinical routine. The aim of this...

Full title: The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: analysis of high-throughput genetic, epigenetic, and gene expression studies Abstract Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) show...

Not sure which forum this should go in. How to cite: Nacul, L.; Authier, J.; Scheibenbogen, C.; Lorusso, L.; Helland, I.; Alegre Martin, J.; Sirbu, C.A.; Mengshoel, A.M.; Polo, O.; Behrends, U.; Nielsen, H.; Grabowski, P.; Sekulic, S.; Sepulveda., N.; Esteves Lopez, F.; Zalewsk, P.; Pheby, D...

https://www.mdpi.com/2077-0383/9/8/2443