Glenton C, Lewin S, Downe S, et al. Cochrane Effective Practice and Organisation of Care (EPOC) Qualitative Evidence Syntheses, Differences From Reviews of Intervention Effectiveness and Implications for Guidance. International Journal of Qualitative Methods. January 2022...
Now published. https://www.s4me.info/threads/assessing-functional-capacity-in-me-cfs-a-patient-informed-questionnaire-funcap-2024-sommerfelt-et-al.35464/page-3#post-538060
The discussion thread before the preprint was published and the preprint thread have been merged.
Discussion of the...
Kinds of Replication: Examining the Meanings of “Conceptual Replication” and “Direct Replication
Maarten Derksen, Jill Morawski
Abstract
Although psychology’s recent crisis has been attributed to various scientific practices, it has come to be called a “replication crisis,” prompting extensive...
As the title indicates.
Proponents of therapist delivered treatments like psychotherapy or exercise repeatedly rejected the argument that relying solely on subjective outcomes in open label trials to assess the effectiveness of said treatments was a bad idea.
In their criticism on the NICE...
Anker, S D, Agewall, S, Borggrefe M et al, 2014, The importance of patient-reported outcomes: a call for their comprehensive integration in cardiovascular clinical trials, European Heart Journal, Volume 35, Issue 30, 7 August 2014, Pages 2001–2009, https://doi.org/10.1093/eurheartj/ehu205...
Full title: Core Outcome Set for Research and Clinical Practice in Post COVID-19 Condition (Long COVID): An International Delphi Consensus Study ‘PC-COS’
Abstract
Background: Recent data suggest that many people experience Post COVID-19 Condition (Long COVID) following the acute phase of the...
I am raising this topic for discussion because I think there are fundamental problems with the design and use of questionnaires in ME/CFS and other medical research.
Questions for consideration:
1. Should questionnaires ever be used to draw conclusions about psychological factors affecting...
Implanted spinal neuromodulation interventions for chronic pain in adults - O'Connell, NE - 2021 | Cochrane Library
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD013756.pub2/full
Background
Implanted spinal neuromodulation (SNMD) techniques are used in the treatment of...
An article about the paper
Doctors Often Prescribe Placebos. But How Well Do They Work?
An Australian researcher argues that the medical community has enshrined placebos as “mysterious and highly effective” in clinical care on the basis of flawed research.
By Oscar Schwartz
The New York Times...
Abstract
Background
Trial monitoring is an important component of good clinical practice to ensure the safety and rights of study participants, confidentiality of personal information, and quality of data. However, the effectiveness of various existing monitoring approaches is unclear...
Abstract
We surveyed all articles in the Journal of Personality and Social Psychology (JPSP), Psychological Science (PS), and the Journal of Experimental Psychology: General (JEP:G) that mentioned the term “Likert,” and found that 100% of the articles that analyzed ordinal data did so using a...
Abstract
Background
Patient and public involvement can improve study outcomes, but little data have been collected on why this might be. We investigated the impact of the Feasibility and Support to Timely Recruitment for Research (FAST-R) service, made up of trained patients and carers who...
Demographic Correlates of Fatigue in the US General Population: Results from the Patient-Reported Outcomes Measurement Information System (PROMIS) Initiative
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744100/. free access
Abstract
Objective
To investigate demographic correlates of fatigue...
This is an interesting editorial in the European Journal of Hospital Pharmacy:
"Red for danger in systematic reviews?" by Andrew Moore
The full article is available here: https://ejhp.bmj.com/content/ejhpharm/28/6/299.full.pdf
I thought it could be of interest to some people here, though I only had a very quick look myself.
172 pages.
https://www.journalslibrary.nihr.ac.uk/hta/hta25570#/full-report
Full title:
Adverse event recording failed to reflect potential harms: a review of trial protocols of behavioral, lifestyle and psychological therapy interventions...
Abstract
Background
Measurement can affect the people being measured; for example, asking people to complete a questionnaire can result in changes in behaviour (the ‘question–behaviour effect’). The usual methods of conduct and analysis of randomised controlled trials implicitly assume that the...
We have previously discussed interventions that manipulate how patients report symptoms as a separate form of bias, rather than as part of the placebo effect.
Critics of the placebo effect have pointed out that according to the available evidence, "placebo effects are weak: regression to the...
Strong Inference
Certain systematic methods of scientific thinking may produce much more rapid progress than
others.
John R. Platt
Science, October 1964.
https://pubmed.ncbi.nlm.nih.gov/17739513/
http://pages.cs.wisc.edu/~markhill/science64_strong_inference.pdf
Personal comment: the more...
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