research methodology

  1. C

    Impact Factor Manipulation

    Wasn't sure where to put this, it's important in understanding what does and does not get published - twitter thread:
  2. MSEsperanza

    Cochrane Effective Practice and Organisation of Care (EPOC) Qualitative Evidence Syntheses [...] 2022, Glenton et al

    Glenton C, Lewin S, Downe S, et al. Cochrane Effective Practice and Organisation of Care (EPOC) Qualitative Evidence Syntheses, Differences From Reviews of Intervention Effectiveness and Implications for Guidance. International Journal of Qualitative Methods. January 2022...
  3. Midnattsol

    Assessing Functional Capacity in [ME/CFS]: A Patient Informed Questionnaire [FUNCAP], 2024, Sommerfelt et al

    Now published. https://www.s4me.info/threads/assessing-functional-capacity-in-me-cfs-a-patient-informed-questionnaire-funcap-2024-sommerfelt-et-al.35464/page-3#post-538060 The discussion thread before the preprint was published and the preprint thread have been merged. Discussion of the...
  4. C

    Kinds of Replication: Examining the Meanings of “Conceptual Replication” and “Direct Replication, 2022, Derksen & Merawski

    Kinds of Replication: Examining the Meanings of “Conceptual Replication” and “Direct Replication Maarten Derksen, Jill Morawski Abstract Although psychology’s recent crisis has been attributed to various scientific practices, it has come to be called a “replication crisis,” prompting extensive...
  5. MSEsperanza

    What's the difference between using symptoms for making a diagnosis in clinical care vs measuring a treatment effect in clinical trials? (Discussion)

    As the title indicates. Proponents of therapist delivered treatments like psychotherapy or exercise repeatedly rejected the argument that relying solely on subjective outcomes in open label trials to assess the effectiveness of said treatments was a bad idea. In their criticism on the NICE...
  6. MSEsperanza

    The importance of patient-reported outcomes: a call for their comprehensive integration in cardiovascular clinical trials, 2014, Anker et al

    Anker, S D, Agewall, S, Borggrefe M et al, 2014, The importance of patient-reported outcomes: a call for their comprehensive integration in cardiovascular clinical trials, European Heart Journal, Volume 35, Issue 30, 7 August 2014, Pages 2001–2009, https://doi.org/10.1093/eurheartj/ehu205...
  7. Andy

    Core Outcome Set for Research and Clinical Practice in Post COVID-19 Condition (Long COVID): ... ‘PC-COS’, 2022, Munblit et al

    Full title: Core Outcome Set for Research and Clinical Practice in Post COVID-19 Condition (Long COVID): An International Delphi Consensus Study ‘PC-COS’ Abstract Background: Recent data suggest that many people experience Post COVID-19 Condition (Long COVID) following the acute phase of the...
  8. Trish

    Questionnaires - design, validation and use in ME/CFS research - discussion thread

    I am raising this topic for discussion because I think there are fundamental problems with the design and use of questionnaires in ME/CFS and other medical research. Questions for consideration: 1. Should questionnaires ever be used to draw conclusions about psychological factors affecting...
  9. MSEsperanza

    Implanted spinal neuromodulation interventions for chronic pain in adults, 2021, O'Connell (Cochrane)

    Implanted spinal neuromodulation interventions for chronic pain in adults - O'Connell, NE - 2021 | Cochrane Library https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD013756.pub2/full Background Implanted spinal neuromodulation (SNMD) techniques are used in the treatment of...
  10. C

    Placebos in clinical care: a suggestion beyond the evidence, 2021, Maher et al

    An article about the paper Doctors Often Prescribe Placebos. But How Well Do They Work? An Australian researcher argues that the medical community has enshrined placebos as “mysterious and highly effective” in clinical care on the basis of flawed research. By Oscar Schwartz The New York Times...
  11. Sly Saint

    Cochrane systematic review: Monitoring strategies for clinical intervention studies, 2021, Klatte et al

    Abstract Background Trial monitoring is an important component of good clinical practice to ensure the safety and rights of study participants, confidentiality of personal information, and quality of data. However, the effectiveness of various existing monitoring approaches is unclear...
  12. ME/CFS Skeptic

    Analyzing ordinal data with metric models: What could possibly go wrong?, Liddell et al. 2018

    Abstract We surveyed all articles in the Journal of Personality and Social Psychology (JPSP), Psychological Science (PS), and the Journal of Experimental Psychology: General (JEP:G) that mentioned the term “Likert,” and found that 100% of the articles that analyzed ordinal data did so using a...
  13. Sly Saint

    How to make study documents clear and relevant: the impact of patient involvement, 2021, Jilka et al

    Abstract Background Patient and public involvement can improve study outcomes, but little data have been collected on why this might be. We investigated the impact of the Feasibility and Support to Timely Recruitment for Research (FAST-R) service, made up of trained patients and carers who...
  14. Hutan

    Demographic Correlates of Fatigue in the US General Population: Results from the PROMIS Initiative, 2011, Junghaenel et al

    Demographic Correlates of Fatigue in the US General Population: Results from the Patient-Reported Outcomes Measurement Information System (PROMIS) Initiative https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744100/. free access Abstract Objective To investigate demographic correlates of fatigue...
  15. ME/CFS Skeptic

    Red for danger in systematic reviews?, 2021, Andrew Moore

    This is an interesting editorial in the European Journal of Hospital Pharmacy: "Red for danger in systematic reviews?" by Andrew Moore The full article is available here: https://ejhp.bmj.com/content/ejhpharm/28/6/299.full.pdf
  16. Esther12

    [NIHR/MRC document] Framework for the development and evaluation of complex interventions, 2021, Skivington et al

    I thought it could be of interest to some people here, though I only had a very quick look myself. 172 pages. https://www.journalslibrary.nihr.ac.uk/hta/hta25570#/full-report
  17. J

    Adverse event recording failed to reflect potential harms: review trial protocols psychosocial interventions, 2021, Papaioannou, Cooper et al

    Full title: Adverse event recording failed to reflect potential harms: a review of trial protocols of behavioral, lifestyle and psychological therapy interventions...
  18. Andy

    Reducing bias in trials from reactions to measurement: the MERIT study including developmental work and expert workshop, 2021, French et al

    Abstract Background Measurement can affect the people being measured; for example, asking people to complete a questionnaire can result in changes in behaviour (the ‘question–behaviour effect’). The usual methods of conduct and analysis of randomised controlled trials implicitly assume that the...
  19. cassava7

    Placebo effect: a psychosomatic component, or only an aggregate of other biases?

    We have previously discussed interventions that manipulate how patients report symptoms as a separate form of bias, rather than as part of the placebo effect. Critics of the placebo effect have pointed out that according to the available evidence, "placebo effects are weak: regression to the...
  20. Snow Leopard

    Public Strong Inference Certain systematic methods of scientific thinking may produce much more rapid progress than others, Platt, 1964

    Strong Inference Certain systematic methods of scientific thinking may produce much more rapid progress than others. John R. Platt Science, October 1964. https://pubmed.ncbi.nlm.nih.gov/17739513/ http://pages.cs.wisc.edu/~markhill/science64_strong_inference.pdf Personal comment: the more...
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